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A 32-year-old woman is cancer-free after undergoing the UK’s first liver transplant for advanced bowel cancer.

Bianca Perea, a trainee lawyer from Manchester, was diagnosed with the most advanced kind of bowel cancer in November 2021, with doctors telling her they aimed to prolong her life rather than find a cure.

But, alongside other treatments including targeted drug therapy, chemotherapy and surgery, the transplant has been a huge success and Ms Perea now has no signs of cancer anywhere in her body.

Ms Perea first visited her GP in Wigan after feeling constipated and bloated. After tests, a colonoscopy and a biopsy, she was diagnosed with stage four bowel cancer, which had spread to all eight segments of her liver.

Ms Perea accepted the diagnosis, but said she refused to believe the outlook was so bleak.

“I don’t want to sound kind of ignorant or arrogant or anything like that but I just didn’t feel in my gut that that was going to be it,” she said.

Her mother asked about a possible transplant at that stage but was told it was not a feasible treatment.

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Ms Perea had 37 rounds of a targeted drug called panitumumab plus chemotherapy for two and a half years.

She had an excellent response to the treatment, which meant she was able to have an operation in May 2023 to remove the bowel tumour.

But scans showed she still had tumours in her liver, which could not be operated on.

EMBARGOED TO 0001 MONDAY JANUARY 6 Undated handout photo issued by The Christie NHS Foundation Trust of Bianca Perea who is cancer-free after undergoing the UK's first liver transplant for advanced bowel cancer. Bianca, a 32-year-old trainee lawyer from Manchester, was given the surgery in the hope it could offer a potential cure for her deadly disease. Issue date: Monday January 6, 2025.
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Bianca with her beloved dog. Pic: PA

Nevertheless, because her response to chemotherapy had been so good and her bowel cancer was seemingly gone, doctors began to look at liver transplants.

Ms Perea was added to the transplant list in February 2024 and was lucky enough to find a donor last summer.

File photo dated 30/11/17 of an NHS Blood and Transplant Small Human Organ in Transit box at St George's Hospital in Tooting, west London. Some 35 human organs were made available for transplant after being donated over Christmas Eve and Christmas Day, new figures have shown. The organs were provided by 11 donors across the UK after their death and included a heart, lungs, kidneys, livers, pancreas and bowel, NHS Blood and Transplant (NHSBT) said. Issue date: Friday December 27, 2024.
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An NHS Blood and Transplant Small Human Organ in Transit box at St George’s Hospital in Tooting, west London. File pic: PA

She said: “Within four weeks of going under the knife, I was able to drive and walk the family dogs, it was really quite incredible.

“To go from being told I’d only have a short time to live to now being cancer-free is the greatest gift.

“I’ve been given a second chance at life and I’m going to grab it with both hands. I am so grateful to the family who agreed to donate their loved one’s liver.

“I do believe this is a cure. They’re always hesitant to say that, obviously, but I am cancer-free right now.”

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Now, Ms Perea is looking forward to going on holiday this year and is working on improving her fitness.

“My liver is doing really well,” she said. “I get tests on that, and I’ve just had my second scan and that’s all clear, so it’s really good.”

Dr Kalena Marti, Ms Perea’s oncologist, said: “To see that Bianca has had such a positive outcome is wonderful.

“When we looked at the tumour cells in her liver after it had been removed, they weren’t active.

“This is excellent news, and we hope that this means that the cancer won’t come back.”

She added: “Advanced bowel cancer is complex and there are lots of different types of the disease, so what works for one person might not work for another. As a result, it’s important that we continue to develop new treatments.

“Thanks to the generosity of organ donors and their loved ones, we can now access liver transplants for some patients, which is fantastic.”

You can watch a full interview with Ms Perea at 8.30am this morning on Sky News Breakfast.

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UK

Royal Navy intercepts Russian warship and tanker

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Royal Navy intercepts Russian warship and tanker

A Royal Navy patrol ship has intercepted two Russian vessels off the UK coast, the Ministry of Defence has said.

It comes after Defence Secretary John Healey announced last Wednesday that lasers from Russian spy ship the Yantar were directed at RAF pilots tracking it, in an attempt to disrupt the monitoring.

The MoD said on Sunday that in a “round-the-clock shadowing operation”, the Royal Navy ship HMS Severn has intercepted Russian warship RFN Stoikiy and tanker Yelnya off the UK coast in the past fortnight.

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Russian ship ‘directed lasers at our pilots’

The Russian vessels sailed through the Dover Strait and westward through the English Channel, the MoD said.

HMS Severn later handed over monitoring duties to a NATO ally off the coast of Brittany, France, it said, but continued to watch from a distance and remained ready to respond to any unexpected activity.

The ministry added that the UK’s armed forces are on patrol “from the English Channel to the High North” amid increased Russian activity threatening UK waters.

Last week, Russia accused the British government of “provocative statements” after the defence secretary warned the Yantar was nearing the UK.

At a news conference in Downing Street on Wednesday, Mr Healey said the spy ship was on the edge of British waters north of Scotland, having entered wider UK waters over the last few weeks.

He said it was the second time this year the Yantar had been deployed off the UK coast and he claimed it was “designed for gathering intelligence and mapping our undersea cables”.

HMS Severn tracking of Russian corvette RFN Stoikiy and tanker Yelnya off the UK coast. Pic: MoD
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HMS Severn tracking of Russian corvette RFN Stoikiy and tanker Yelnya off the UK coast. Pic: MoD

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Mr Healey said the ship had “directed lasers” at pilots of a P-8 surveillance aircraft monitoring its activities – a Russian action he deemed “deeply dangerous”.

In a clear message to Russian President Vladimir Putin, the defence secretary said: “We see you. We know what you are doing. And we are ready.”

The ministry said while tracking the Yantar, Royal Navy frigate HMS Somerset and other civilian ships in the area “experienced GPS jamming in a further demonstration of unprofessional behaviour, intended to be disruptive and a nuisance”.

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What is Russian spy ship up to?

Russia’s UK embassy dismissed the accusations and insisted the Yantar is a research ship in international waters.

The defence secretary also repeated government plans to increase defence spending and work with NATO allies to bolster European security.

And he stressed how plans to buy weapons and build arms factories will create jobs and economic growth.

HMS Somerset flanking Russian ship the Yantar near UK waters on 22 January 2025. File pic: Royal Navy/PA
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HMS Somerset flanking Russian ship the Yantar near UK waters on 22 January 2025. File pic: Royal Navy/PA

A report by a group of MPs, also released on Wednesday, underlined the scale of the challenge the UK faces.

It accused the government of lacking a national plan to defend itself from attack.

The Defence Select Committee also warned that Mr Healey, the prime minister and the rest of the cabinet are moving at a “glacial” pace to fix the issue and are failing to launch a “national conversation on defence and security” – something Sir Keir Starmer had promised last year.

Russian ship the Yantar transiting through the English Channel. File pic: MoD
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Russian ship the Yantar transiting through the English Channel. File pic: MoD

The UK has seen a 30% increase in Russian vessels threatening UK waters in the past two years, according to the MoD.

But the ministry maintained the UK has a wide range of military options at its disposal to keep UK waters safe.

Three RAF P-8 Poseidon aircraft have deployed to Keflavik Air Base in Iceland in the largest overseas deployment of the RAF P-8 fleet so far, the MoD said.

They are conducting surveillance operations as part of NATO’s collective defence, patrolling for Russian ships and submarines in the North Atlantic and Arctic.

The operations come just weeks after HMS Duncan tracked the movements of Russian destroyer Vice Admiral Kulakov, and frigate HMS Iron Duke was dispatched to monitor Russian Kilo-class submarine Novorossiysk.

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UK

Ban on Maccabi Tel Aviv fans for Aston Villa game ‘based on false hooligan claims’

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Ban on Maccabi Tel Aviv fans for Aston Villa game 'based on false hooligan claims'

West Midlands Police has defended the ban on Maccabi Tel Aviv fans attending an Aston Villa match after it was claimed that false intelligence was used.

Supporters of the Israeli club were barred from the Europa League fixture at Villa Park on 6 November.

West Midlands Police chief superintendent Tom Joyce told Sky News before the game that a “section” of Maccabi’s fanbase engaged in “quite significant levels of hooliganism”.

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‘Hooliganism’ blamed for Maccabi Tel Aviv ban

According to The Sunday Times, West Midlands Police claimed in a confidential dossier that when Maccabi played Ajax in Amsterdam last year, Israeli fans threw “innocent members of the public into the river”, and added that between 500 and 600 supporters had “intentionally targeted Muslim communities”.

The report also said 5,000 Dutch police officers had been deployed in response.

However, the Netherlands’ national police force has questioned the claims, reportedly describing information cited by its British officers as “not true” and in some instances obviously inaccurate.

Sebastiaan Meijer, a spokesman for the Amsterdam division, told The Sunday Times that he was “surprised” by allegations in the West Midlands Police report, which had linked 200 travelling supporters to the Israel Defence Forces (IDF).

Mr Meijer denied that his force had such intelligence, adding that the claim was meaningless given the country had a policy of conscription.

Also, Mr Meijer said that Amsterdam’s force “does not recognise” the claim in the British report, attributed to Dutch law enforcement, that Israelis were “highly organised, skilled fighters with a serious desire and will to fight with police and opposing groups”.

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Heavy police presence for Aston Villa v Maccabi Tel Aviv

The Dutch police added that the only known case of a fan being in the river appeared to involve a Maccabi supporter. While being filmed, he was told he could leave the water on the condition that he said “Free Palestine”.

In an interview with Sky News before the game, West Midlands Police referenced disorder when Maccabi played Ajax in Amsterdam last November.

Mr Joyce said ahead of the Villa Park match: “We’ve had examples where a section of Maccabi fans were targeting people not involved in football matches, and certainly we had an incident in Amsterdam last year which has informed some of our decision-making.

“So it is exclusively a decision we made on the basis of the behaviour of a sub-section of Maccabi fans, but all the reaction that could occur obviously formed part of that as well.”

Pro-Israel supporters are led away from Villa Park before a Europa League tie on 6 November. Pic: PA
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Pro-Israel supporters are led away from Villa Park before a Europa League tie on 6 November. Pic: PA

Maccabi’s visit to Birmingham came amid heightened tensions due to Israel’s war on Hamas in Gaza.

A safety advisory group (SAG) recommended that Maccabi fans should be banned from attending the fixture on the advice of the police. The ban drew criticism, and Prime Minister Sir Keir Starmer said it was the “wrong decision”.

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Mounted police outside Villa Park for the game. Pic: PA
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Mounted police outside Villa Park for the game. Pic: PA

West Midland Police’s statement in full

Following The Sunday Times report, West Midlands Police stood by its “information and intelligence”, adding that the “Maccabi Fanatics… posed a credible threat to safety”.

In a statement to Sky News, the force said: “West Midlands Police’s evaluation was based primarily on information and intelligence and had public safety at its heart.

“We assessed the fixture between Ajax and Maccabi Tel Aviv in Amsterdam as having involved significant public disorder.

“We met with Dutch police on 1 October, where information relating to that 2024 fixture was shared with us.

“Informed by information and intelligence, we concluded that Maccabi Tel Aviv supporters – specifically the subgroup known as the Maccabi Fanatics – posed a credible threat to public safety.

“The submission made to the SAG safety advisory group was based on information and intelligence which helped shape understanding of the risks.

“West Midlands Police commissioned a peer review, which was conducted by UKFPU [United Kingdom Policing Unit], the NPCC [National Police Chiefs’ Council] and subject matter experts.

“This review, carried out on 20 October, fully endorsed the force’s approach and decision-making.

“We are satisfied that the policing strategy and operational plan was effective, proportionate, and maintained the city’s reputation as a safe and welcoming place for everyone.”

Sky News has approached Dutch police for comment.

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UK

Titanic couple’s pocket watch sells for record £1.78m

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Titanic couple's pocket watch sells for record £1.78m

A gold pocket watch that belonged to an elderly couple who drowned as the Titanic sunk has sold for a record-breaking £1.78m at auction.

The 18-carat Jules Jurgensen engraved watch was owned by first class passenger Isidor Straus, who died when the ship sank in April 1912.

He and his wife Ida were portrayed in the film Titanic as a couple who held each other as the ship went down.

When he was offered a seat on a lifeboat due to his age, he replied that he would not go before other men.

His wife refused to leave him, and the couple were last seen alive sitting on deckchairs, facing fate by each other’s side.

They were among very few first class passengers to perish in the disaster.

The watch was recovered from Mr Straus’s body along with other personal items and returned to his family.

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It had been a present for his 43rd birthday in 1888 – the same year he became a partner in the New York department store, Macy’s.

A letter written by Mrs Straus on Titanic stationery and posted while onboard. Pic: PA
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A letter written by Mrs Straus on Titanic stationery and posted while onboard. Pic: PA

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The watch, which had remained in the couple’s family, was sold at Henry Aldridge & Son Auctioneers in Devizes, Wiltshire.

The £1.78m for the item is the highest amount ever paid for Titanic memorabilia, according to the company.

A letter written by Mrs Straus on Titanic stationery and posted while onboard the ship fetched £100,000.

The previous record was set last year when another gold pocket watch presented to the captain of a boat that rescued over 700 passengers from the liner sold for £1.56m.

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