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Thousands of men are to be checked for prostate cancer in one of the first large-scale European trials of smart screening.

The pilot study, starting next week in Ireland, will combine a blood test with personal risk factors and an MRI scan to increase the accuracy of screening men in their 50s and 60s.

Up to now health experts have rejected population screening in the belief that the benefits of earlier cancer detection were outweighed by the risks that some men could have unnecessary biopsies and risky treatment they don’t need.

But the PRAISE-U study is an attempt to save lives in a more targeted way, filtering out men who don’t have cancer at an early stage, so they don’t come to any harm.

David Galvin, the head of the study and a surgeon at the Mater Hospital in Dublin, told Sky News that a safe, effective screening strategy was urgently needed.

“There is a tsunami of elderly patients coming towards us,” he said.

“There’s going to be a sharp rise in prostate cancer unless we have a way to detect the disease early and not burden our health care services with vast numbers of scans and biopsies.”

David Galvin, consultant urologist at The Mater Hospital in Dublin
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David Galvin, consultant urologist at The Mater Hospital in Dublin

Thousands diagnosed too late

Prostate cancer is the most common cancer in men in Ireland. In the UK it is now the most common of all cancers, causing more deaths than breast cancer.

There are no symptoms in the early stages. Around 12,000 men a year in the UK alone are diagnosed too late to cure.

Studies have shown that a blood test for a prostate protein called PSA can diagnose cases at an earlier stage, reducing deaths by 40%.

But not all men with cancer have high levels of the PSA protein.

And conversely, high levels can also be caused by other prostate conditions, infections, exercise and sexual activity.

An example of a prostate tumour seen on a MRI scan
Image:
An example of a prostate tumour seen on a MRI scan

The unreliability of the test has held back its use for screening.

But in the Irish pilot study, men will be scored by their PSA level and whether they have other risk factors such as black ethnicity or a family history.

Those at low risk will be retested in future.

Around half of the men will undergo a detailed MRI scan of their prostate to check for tumours – and only half those will then need a biopsy, in which a needle is inserted to extract cells for a precise diagnosis.

Professor Galvin said the multi-stage screening meant only those who really need a biopsy will have one.

“I worked out that if you have the PSA test, there’s about a 1 in 40 chance that you will ultimately need a biopsy.

“The other 39 men are reassured that testing is all normal and they don’t have any clinically significant disease.”

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‘I got away with it by the skin of my teeth’

The PRAISE-U study is backed by the European Association of Urology and funded by the EU.

Around 8,000 men in Waterford and two areas of Dublin will be randomly invited for screening over the next year.

Tony Ward, a rugby legend and one of the best number 10s to play for Ireland, was diagnosed with an aggressive prostate cancer just over a decade ago. Even now he needs daily treatment and regular scans.

He told Sky News screening to detect cancer at an earlier stage is desperately needed.

“It’s everything, it’s massive,” he said.

“I did not have the early diagnosis, but I got away with it by the skin of my teeth.”

Thomas Moore speaking to Tony Ward
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Thomas Moore speaking to Tony Ward

‘Very curable cancer kills 12,000 men every year’

The UK’s National Screening Committee, which advises the Department of Health, is reviewing the evidence on prostate cancer screening. But it’s already taken two years, and a decision still isn’t due until the end of 2025.

Chiara De Biase, director of health services, equity and improvement from Prostate Cancer UK, said men were dying unnecessarily as a result.

She said: “12,000 men die every year from what is – when caught in its earliest stages – a very, very curable cancer.

“We think the evidence [for screening] is there and we can’t see why this has taken so long.”

Chiara De Biase, from Prostate Cancer UK
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Chiara De Biase, director of health services, equity & improvement from Prostate Cancer UK

A spokesperson for the UK government’s Department of Health and Social Care said: “Prostate cancer patients are waiting too long for diagnosis and treatment, and we are determined to change that.

“Our National Cancer Plan will transform the way we treat cancer, making the UK a world leader in cancer survival by fighting the disease on all fronts, through improving research, diagnosis, screening, treatment and prevention.

“The UK National Screening Committee is reviewing the evidence for prostate cancer screening programmes, including targeted approaches for men at higher risk.”

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‘I don’t remember feeling this unsafe’: Frightened worshippers too scared to walk the streets

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'I don't remember feeling this unsafe': Frightened worshippers too scared to walk the streets

“I don’t remember feeling this unsafe ever before,” says 76-year-old devout Sikh Resham Kaur who moved to the UK from India when she was 18.

She’s waiting for two men to walk her home from the gurdwara – a Sikh place of worship – at a time of rising fears over physical and verbal racial abuse.

Resham reaches for her walking stick and puts on her shoes.

Sarbjit Singh and Mangat Singh walking Resham Kaur home from the gurdwara
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Sarbjit Singh and Mangat Singh walking Resham Kaur home from the gurdwara

Monty Singh says they are 'not vigilantes'
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Monty Singh says they are ‘not vigilantes’

“When I came to this country, I didn’t fear for my safety. But now I do – every day. It’s a lot worse now,” she says.

It’s a disturbing admission at a time when some fear Britain’s communities are more fragmented than ever.

It comes as new figures last week revealed religious hate crime recorded by police in England and Wales has reached a record high.

Two volunteers arrive, opening the exit door for Resham at the gurdwara in Smethwick in the West Midlands.

Sarbjit Singh – who works in a bakery – and Mangat Singh – who works at a salad farm – are part of the congregation and walk people to and from the gurdwara on their days off to keep them safe.

With attendance numbers at the gurdwara falling because of safety fears, Sarbjit says it’s something they need to do “until we get a bit of peace and tranquillity back in society and the community”.

“We have to do something. We can’t just sit in silence. And we can’t let the congregation just stay at home,” Sarbjit says.

The Oldbury patrol
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The Oldbury patrol

Other groups of Sikh men are also taking action – joining patrols along a road in nearby Oldbury where a young Sikh woman was allegedly raped a few weeks ago.

That alleged attack – and an assault on two taxi drivers in Wolverhampton in August – have horrified the Sikh community. Police are treating both incidents as racially aggravated.

Two Sikh taxi drivers were allegedly assaulted in Wolverhampton in August
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Two Sikh taxi drivers were allegedly assaulted in Wolverhampton in August

Monty Singh, who is taking part in the patrols, says they are “not vigilantes”.

“We need to make it crystal clear that we’re good people, we’re just trying to do the right thing and support our community,” Monty adds.

Pervinder Kaur is the vice president of the gurdwara.

Pervinder Kaur said before the summer people felt safe, but racial abuse is being emboldened
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Pervinder Kaur said before the summer people felt safe, but racial abuse is being emboldened

She believes racial abuse is being emboldened after a summer of demonstrations outside hotels housing asylum seekers and renewed debate about immigration.

“People are more verbal about it now. They are not scared of the consequences,” she said.

A sense of vulnerability is common among minority communities and security measures have also been stepped up at mosques around the country.

Iman Adam Kantar said 'the Union Jack is our flag'
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Iman Adam Kantar said ‘the Union Jack is our flag’

Friday prayers at the Rumi Mosque in Edmonton, north London
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Friday prayers at the Rumi Mosque in Edmonton, north London

Imam Adam Kantar from the Rumi Mosque in Edmonton, north London, said: “Many people are now telling their children not to be outside after certain hours.

“Their [husbands], they prefer to go shopping instead of their hijab [wearing] wives and spouses.

“We have to engage with the wider community and prove that we love this country and its people. The Union Jack is our flag.”

What Britain’s fragmented society has in common is fear among minority communities – even if the causes are different.

Rabbi Josh Levy, the co-lead of Progressive Judaism, has spent years trying to advance interfaith dialogue.

He said: “Single individual(s) or small groups can cause a huge amount of pain and distress.

“There are lots of really great examples of community cohesion around the country. But generally, there is definitely a sense of fragmentation. And whether it’s driven by political concerns or what’s happening internationally.

“We’ve got huge work to do in taking the work that happens on a national level and bringing it into local communities.”

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‘Make or break’: Chancellor warned businesses can’t take more tax hikes in budget

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'Make or break': Chancellor warned businesses can't take more tax hikes in budget

Rachel Reeves has been warned that firms face a “make-or-break moment” at next month’s budget.

The British Chamber of Commerce (BCC) urged the chancellor, who is widely expected to announce tax hikes in November’s budget to fill a gap in the public finances, to steer clear of increasing levies on businesses.

Ms Reeves raised taxes by £40bn last year and the BCC said business confidence had not recovered since.

“Last year’s budget took the wind from their sails, and they have been struggling to find momentum ever since,” BCC director-general Shevaun Haviland said.

She said firms felt “drained” and could not plan ahead as they expected “further tax demands to be laid at their feet” when the budget is delivered on 26 November.

“The chancellor must seize this moment and use her budget to deliver a pro-growth agenda that can restore optimism and belief amongst business leaders,” Ms Haviland added.

“This year’s budget will be a make-or-break moment for many firms.”

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The BCC also called for a reform of business rates and the removal of the windfall tax on gas and oil introduced by the last government.

In its submission, the industry body outlined more than 60 recommendations, including the proposal of further infrastructure investment, cuts to customs barriers and action on skill shortages.

Earlier this year, Prime Minister Sir Keir Starmer announced Labour would aim to approve 150 major infrastructure projects by the next election, with Labour already pledging to support expansions of both Heathrow and Gatwick airports – another of the BCC’s requests.

While the Treasury would not comment on budget speculation, a spokesperson insisted Ms Reeves would “strike the right balance” between ensuring funding for public services and securing economic growth.

She has vowed to stick to Labour’s manifesto pledges not to raise taxes on “working people”.

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Household spending on the wane

The BCC’s plea to halt further tax rises on businesses comes as retail sales growth slowed in September.

“With the budget looming large, and households facing higher bills, retail spending rose more slowly than in recent months,” Helen Dickinson, chief executive of the British Retail Consortium (BRC), said.

“Rising inflation and a potentially taxing budget is weighing on the minds of many households planning their Christmas spending.”

Total retail sales in the UK increased by 2.3% year-on-year in September, against growth of 2% in September 2024 and above the 12-month average growth of 2.1%, according to BRC and KPMG data.

While food sales were up by 4.3% year-on-year, this was largely driven by inflation rather than volume growth.

Non-food sales growth slowed to 0.7% against the growth of 1.7% last September, making it below the 12-month average growth of 0.9%.

Total retail sales in the UK increased in September compared to the year before. File pic: PA
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Total retail sales in the UK increased in September compared to the year before. File pic: PA

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Online non-food sales only increased by 1% against last September’s growth of 3.4%, which was below the 12-month average growth of 1.8%.

“The future of many large anchor stores and thousands of jobs remains in jeopardy while the Treasury keeps the risk of a new business rates surtax on the table,” Ms Dickinson said.

“By exempting these shops when the budget announcements are made, the chancellor can reduce the inflationary pressures hammering businesses and households alike.”

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Thousands of homes now need repairs after insulation fitted under government scheme

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Thousands of homes now need repairs after insulation fitted under government scheme

Thousands of homes fitted with insulation under a flagship government scheme now need major remedial work, or risk damp and mould, the public spending watchdog has warned.

A damning report by the National Audit Office (NAO) said “clear failures” in the Energy Company Obligation (ECO) scheme to tackle fuel poverty and pollution had led to low quality installations and even potential fraud.

It blamed incompetent subcontractors and weak monitoring and government oversight for the issues, which in extreme cases could cause fires.

Fuel poverty campaigners warned the system had “let cowboys through the front door”, saying it must be fixed to bring down energy bills and keep people warm.

Almost all homes – some 98%, affecting 22,000 to 23,000 properties – fitted with external wall insulation under the ECO are affected, the NAO said.

A further 29% of homes with internal wall insulation – around 9,000 to 13,000 dwellings – also face major issues that need fixing.

A small percentage of homes – 6% with external insulation and 2% with internal – put people in immediate danger, such as poor ventilation that could cause carbon monoxide poisoning, and electrical safety issues that could start fires.

ECO is a scheme that obliges energy companies to pay for energy efficiency measures in vulnerable households out of consumer bills.

Gareth Davies, head of the NAO, said ECO is “important to help reduce fuel poverty and meet the government’s ambitions for energy efficiency”.

But “clear failures in the design and set-up” had led to “poor-quality installations, as well as suspected fraud”, he added.

‘Gaming the system’

The report says the reason things had gone so badly wrong could be down to work being subcontracted to individuals and firms who are not competent or certified, uncertainty over standards, and businesses “cutting corners” or “gaming the system”.

The energy regulator Ofgem last year estimated businesses had falsified claims for ECO installations in between 5,600 and 16,500 homes.

That means they could have claimed between £56m and £165m from energy suppliers – ultimately paid for by bill-payers.

More than 20,000 homes are said to be affected. File pic: iStock
Image:
More than 20,000 homes are said to be affected. File pic: iStock

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Martin McCluskey, the government minister for energy consumers, criticised the “unacceptable, systemic failings” that had affected thousands of families.

He added: “We are fixing the broken system the last government left by introducing comprehensive reforms to make this process clear and straightforward, and in the rare cases where things go wrong, there will be clear lines of accountability, so consumers are guaranteed to get any problems fixed quickly.”

The government urged households to take up the free audit that will be offered in a forthcoming letter, and said installers would be forced to remedy the issues free of charge.

However, insulation has the potential to vastly improve homes, analysts pointed out.

Jess Ralston from energy think tank ECIU said: “The majority of households that have benefitted from insulation schemes have lower bills and warmer, healthy homes, particularly during the early years of the gas crisis when the UK’s poor quality housing stock was one of the reasons we were so badly hit compared to other European countries.”

Simon Francis, co-ordinator of the End Fuel Poverty Coalition, said: “Insulation and ventilation, when done properly, are among the safest and most effective ways to bring down energy bills and keep people warm.”

But the report had revealed a “system that has let cowboys through the front door, leaving thousands of victims living in misery and undermining public trust”.

Sue Davies, Which? head of consumer protection policy, called it “a damning indictment of a failed scheme, where poor oversight has allowed rogue traders to cause huge damage to people’s homes and lives”.

She said the government must take swift action to rectify the damage, as well as ensuring “there is no repeat of this scandal by putting in place robust consumer protections and effective oversight”.

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