Gene Hackman’s wife died from a rare infectious disease around a week before the actor died, medical investigators have said.
The couple were found dead in their New Mexico home on 26 February, along with one of their pet dogs. Police have previously said there were no apparent signs of foul play.
At a press conference on Friday, chief medical investigator for New Mexico, doctor Heather Jarrell, gave an update on the results of post-mortem investigations carried out following their deaths.
Doctor Jarrell said Hackman’s wife, Betsy Arakawa, died from hantavirus pulmonary syndrome, a rare infectious disease. There were no signs of trauma and the death was a result of natural causes, she said.
Image: Actor Gene Hackman with his wife, Betsy Arakawa, pictured in 2003. Pic: AP
The doctor said Arakawa likely died on 11 February, the date she was last known to have communicated with people via email.
Due to his Alzheimer’s, “it’s quite possible he was not aware that [his wife] was deceased,” Dr Jarrell added.
The actor tested negative for hantavirus, a rare disease spread by infected rodent droppings.
Image: Gene Hackman in 1999. Pic: AP
Humans can contract hantavirus by breathing in contaminated air, and symptoms can start as soon as one week, or as long as eight weeks, later. It is not transmissible from person to person.
There were just seven confirmed cases of hantavirus in New Mexico last year, and Arakawa is the only person confirmed to have contracted it in the state in 2025. Between 1975 and 2023, New Mexico recorded a total of 129 hantavirus cases, with 52 deaths.
Santa Fe County sheriff Adan Mendoza said authorities are still waiting for data from mobile phones found at the property, but it is “very unlikely they are going to show anything else”.
“There’s no indication” that Hackman used a mobile phone or any other technology to communicate and the couple lived a very private life before their deaths, he added.
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The cause of the couple’s dog’s death has not been confirmed but it is now known that Arakawa had picked the animal up from the vet, where it had undergone a procedure, on 9 February.
The procedure “may explain why [the dog] was in a crate at the residence” while two surviving dogs were found roaming the property, Mr Mendoza said.
Hackman, who was widely respected as one of the greatest actors of his generation, was a five-time Oscar nominee who won the best actor in a leading role for The French Connection in 1972 and best actor in a supporting role for Unforgiven two decades later.
It is “pretty surreal”, Academy Award winner Reese Witherspoon admits, finding herself at the top of The New York Times bestsellers list.
When I meet the actress alongside her co-writer, best-selling author Harlan Coben, overnight the pair have learned that their thriller is now at number one.
He jokes: “I was texting her last night and saying you’ll now have to call yourself number one bestselling novelist, forget about Oscar winner!”
Image: Reese Witherspoon and Harlan Coben told Katie Spencer about their novel Gone Before Goodbye
As one of the most successful authors in the world, Coben has sold over 80 million books to date, while for Witherspoon this is new ground.
Not content with running a hugely successful production company responsible for a string of hits, as well as one of the most successful book clubs in the world, she explains she felt compelled to give writing a try.
“People want you to stay in your lane… as a creative person I think it’s impossible to just choose one kind of life.
“Creativity is infinite and who I was as a creative person when I was 20 is very different from the person I am now at 49.”
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Gone Before Goodbye, a thriller about a talented surgeon who finds herself caught up in a deadly conspiracy, is the result of Witherspoon daring to put her head above the parapet.
Image: Witherspoon says she felt compelled to give writing a try
Coben admits he was “a little wary” at first.
“I don’t co-write novels but when she made the pitch and started talking about it, I was like ‘dang that’s good, we can do something with that’.”
While countless celebrities work with ghostwriters, Coben says: “I said to her from day one ‘it’s only going to be you and me in here… no third person in here, I don’t do that’. So every word you [read] comes from Reese and me.”
Image: Coben has sold over 80 million books to date, while for Witherspoon this is new ground
Witherspoon explains: “He was like ‘if we’re going to do this, it’s going to have to be at a really high level because people going to expect a lot, so our bar was really high.”
“I said to her, in the beginning, novels are like a sausage,” Coben laughs. “You might like the final taste, but you don’t want to see how it was made and Reese got to see the full sausage getting made here.”
When it came to writing, Coben says they “fell into a rhythm right away”, working together in three-hour stints, “back and forth with a yellow legal pad – what about this? What about that?”
Image: Coben says they ‘fell into a rhythm right away’
Witherspoon says it “feels really deeply personal” to have their work now in print.
“Usually, as an actor, I walk into other people’s worlds and it’s already set up… but this was creating the whole world with Harlan and just from beginning to end feels very personal.”
While the story seems an obvious fit for being adapted to the screen, perhaps with a certain blonde actress in the leading role, Coben says that was never their intention.
“The biggest, biggest mistake novelists make when you write a book is to say ‘this would make a really great movie’. A book is a book, a movie is a movie, and we both focused on wanting this to be just a great reading experience.”
Given that their collaboration is already selling in big numbers, will the pair team up again to write a second?
Witherspoon says: “Let’s just see what people think of this one first.”
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Associate professor of neurology Dr Laura Stein told Sky’s US partner NBC News: ” The most well-described risk factors include a predisposition [family history of aneurysm], high blood pressure, cigarette smoking and inflammation.”
She went on to explain that most fatal ruptured aneurysms are in the brain, killing about one in three patients.
“When it’s a blood vessel that’s in the head and it bleeds, there’s a much higher risk of having a very bad problem just because the brain is enclosed in a fixed space,” Dr Stein added.
Low-risk aneurysms are monitored by doctors for growth or abnormalities, and there are a series of potential treatment options for those considered dangerous.
Elsewhere in The Kardashians clip, Kim admitted that her ex-husband Kanye West will be in her life “no matter what” because of the four kids they share together.