A baby girl has become the first child in the UK to be born from a womb transplant.
Grace Davidson, who received the transplant in 2023, said the birth of her daughter Amy Isabel was the “greatest gift we could ever have asked for”.
The 36-year-old, from north London, received the donated womb from her older sister, Amy.
It was the first time the procedure had taken place in the UK, and the birth will give hope to thousands of women born without a womb – like those with Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome – or whose womb fails to function.
Image: Grace and Angus Davidson with the hospital team at the birth of baby Amy. Pic: Womb Transplant UK/PA
Amy Isabel was named after her aunt, and a surgeon who helped perfect the technique, and was born by planned caesarean section on 27 February at Queen Charlotte’s and Chelsea Hospital in London.
Mrs Davidson, an NHS dietitian, said she felt “shock” when she first held her daughter, adding: “We have been given the greatest gift we could ever have asked for.
“It was just hard to believe she was real. I knew she was ours, but it’s just hard to believe.
“It sort of feels like there’s a completeness now where there maybe wasn’t before.”
Image: Aunt Amy Purdie (right) with the happy family. Pic: Womb Transplant UK/PA
Her husband Angus, 37, said: “The moment we saw her was incredible, and both of us just broke down in emotional tears – it’s hard to describe, it was elation.
“It had been such a long wait. We’d been intending to have a family somehow since we were married, and we’ve kind of been on this journey for such a long time.”
Womb transplantation is on the way to becoming an acceptable, life-giving procedure
The birth of Amy Isabel is not just a first for the UK, but an important step towards womb transplantation becoming an established medical procedure.
It was little more than a decade ago that the world’s first baby was born following a womb transplant in Sweden.
And not without eyebrows being raised by some in the world of medical ethics.
Not all womb transplants, whether from a living relative or from a deceased donor, are successful. And not all result in successful or uncomplicated pregnancies.
But the surgical team behind this UK success have achieved a one-for-one: a healthy baby born from the first womb transplant ever performed here.
Amy Isabel joins an estimated 50 other babies and children worldwide now born via a womb transplant.
And she won’t be the last.
Around 100 women in at least 10 countries have undergone the procedure – three transplants have taken place in the UK since Amy’s mother became the first in 2023.
A study of 33 womb transplants in the US found 74% of the transplants remained healthy after a year and 80% of those resulted in a successful birth.
But a womb transplant is unlikely to ever become “routine”.
While the number of eligible women – those lacking a functioning uterus but having healthy ovaries – might number in the low thousands in a country the size of the UK, not all would meet the strict medical criteria needed to maximise the chance of a successful transplant and subsequent birth.
And not all might choose it.
A successful birth following a womb transplant involves three major operations. The first to receive the transplanted womb, a caesarean section to deliver the baby, then a hysterectomy to remove the womb once the recipient mother decides to have no more children.
Given a womb transplant isn’t “life-saving”, ethics guidelines require the procedure to be temporary. The long-term risks of organ rejection, and the drugs needed to prevent it, are considered too great once the womb has served its miraculous function.
Some medical ethicists still question the procedure as a whole, arguing it is unnecessarily risky for both the mother and baby, especially babies are born seriously pre-term and at low birth weight.
However, this latest success, and the increasing number of healthy babies born via the procedure worldwide may change that.
Womb transplantation is on the way to becoming an acceptable, life-giving procedure for women who previously had no hope of carrying a baby of their own.
Mrs Davidson was born with Mayer-Rokitansky-Kuster-Hauser, a rare condition that affects around one in every 5,000 women. It means they have an underdeveloped or missing womb.
Image: Grace with her sister Amy (right) and daughter. Pic: Womb Transplant UK/PA
However, the ovaries are intact and still function to produce eggs and female hormones, making conceiving via fertility treatment a possibility.
Before receiving the donated womb, Mrs Davidson and her husband underwent fertility treatment to create seven embryos, which were frozen for In Vitro Fertilisation (IVF) in central London.
Mrs Davidson had surgery in February 2023 to receive the womb from her 42-year-old sister Amy Purdie, who is a mother to two girls aged 10 and six.
Several months later, one of the stored embryos was transferred via IVF to Mrs Davidson.
The baby weighed 4.5lbs and was delivered several weeks early to ensure a safe, hospital-based delivery.
Ms Purdie called the birth of her niece “worth every moment”.
Professor Richard Smith and Isabel Quiroga were the lead surgeons for the womb transplant and both were in the operating theatre when Amy was delivered, with her parents choosing her middle name in honour of Ms Quiroga.
Prof Smith, clinical lead at the charity Womb Transplant UK and consultant gynaecological surgeon at Imperial College Healthcare NHS Trust, told Sky News that being in the operating theatre when Amy was delivered was “really quite remarkable”.
The medic said: “We’ve waited a very, very long time for this, and there’s been quite a lot of tears shed. Ironically the scariest bit of the day for me was when [Amy’s] mum and dad asked me to hold their baby, which was incredible.”
Ms Quiroga, consultant surgeon at the Oxford Transplant Centre, part of Oxford University Hospitals, told Sky News it was “quite a complex procedure” and “the pressure was immense when we did the transplant”.
But she said it was “totally amazing to see all that effort” and it has “been totally worth it”.
The first thing you notice when immigration officers stop a possible illegal moped delivery driver is the speed in which the suspect quickly taps on their mobile.
“We’re in their WhatsApp groups – they’ll be telling thousands now that we’re here… so our cover is blown,” the lead immigration officer tells me.
“It’s like a constant game of cat and mouse.”
Twelve Immigration Enforcement officers, part of the Home Office, are joining colleagues from Avon and Somerset Police in a crackdown on road offences and migrants working illegally.
The West of England and Wales has seen the highest number of arrests over the last year for illegal workers outside of London.
“It is a problem… we’re tackling it,” Murad Mohammed, from Immigration Enforcement, says. He covers all the devolved nations.
“This is just one of the operations going on around the country, every day of the week, every month of the year.”
Image: Murad Mohammed, from Immigration Enforcement, says his team are attempting to tackle the issue
Just outside the Cabot Circus shopping complex, we stop a young Albanian man who arrived in the UK on the back of a truck.
He’s on an expensive and fast-looking e-bike, with a new-looking Just Eat delivery bag.
He says he just uses it for “groceries” – but the officer isn’t buying it. He’s arrested, but then bailed instantly.
We don’t know the specifics of his case, but one officer tells me this suspected offence won’t count against his asylum claim.
Such is the scale of the problem – the backlog, loopholes and the complexity of cases – that trying to keep on top of it feels impossible.
This is one of many raids happening across the UK as part of what the government says is a “blitz” targeting illegal working hotspots.
Angela Eagle, the border security and asylum minister, joins the team for an hour at one of Bristol’sretail parks, scattered with fast food chains and, therefore, delivery bikes.
Image: Border security and asylum minister, Angela Eagle, speaks to Sky News
She says arrests for illegal working are up over the last year by 51% from the year before, to more than 7,000.
“If we find you working, you can lose access to the hotel or the support you have [been] given under false pretences,” she said.
“We are cracking down on that abuse, and we intend to keep doing so.”
There are reports that asylum seekers can rent legitimate delivery-driver accounts within hours of arriving in the country – skipping employment legality checks.
Uber Eats, Deliveroo, and Just Eat all told Sky News they’re continuing to strengthen the technology they use to remove anyone working illegally.
But a new Border Security Bill, working its way through Parliament, could see companies fined £60,000 for each illegal worker discovered, director disqualifications and potential prison sentences of up to five years.
“I had them all in to see me last week and I told them in no uncertain terms that we take a very tough line on this kind of abuse and they’ve got to change their systems so they can drive it out and off their platforms,” the minister tells me.
For some of those who arrive, a bike and a phone provide a way to repay debts to gang masters.
There were eight arrests today in Bristol, one or two taken into custody, but it was 12 hours of hard work by a dozen immigration officers and the support of the police.
As two mopeds are pushed onto a low-loader, you can’t help but feel, despite the best intentions, that at the moment, this is a losing battle.
We see the boat from a distance – the orange of the life jackets reflected in the rising sun.
And as we draw closer, we can make out dozens of people crowded on board as it sets off from the shore, from a beach near Dunkirk.
There is no sign of any police activity on the shore, and there are no police vessels in the water.
Instead, the migrants crammed into an inflatable dinghy are being watched by us, on board a private boat, and the looming figure of the Minck, a French search and rescue ship that soon arrives.
Image: Minck, a French search and rescue ship, shadows the boat
The dinghy meanders. It’s not heading towards Britain but rather hugging the coast.
A few of the passengers wave at us cheerfully, but then the boat starts to head back towards the shore.
Image: Sky’s Adam Parsons at the scene
As it nears a different beach, we see a police vehicle – a dune buggy – heading down to meet it.
Normal practice is for French police officers to slice through the material of any of these small boats that end up back on shore.
Two police officers get out of the buggy and wait. A police helicopter arrives and circles above, performing a tight circle over the heads of the migrants.
The police think they might be about to go back on to the beach; in fact, these passengers know that most of them are staying put.
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The boat stops a short distance from the shore and four people jump out. As they wade towards the beach, the boat turns and starts to head back out to sea.
We see the two police officers approach these four men and have a brief conversation.
They don’t appear to check the bags they are carrying and, if they do question them about why they left the boat, it is the most cursory of conversations.
In reality, these people probably don’t speak French but they were almost certainly involved in arranging this crossing, which is against the law. But all four walk away, disappearing into the dunes at the back of the beach.
The first thing you notice when immigration officers stop a possible illegal moped delivery driver is the speed in which the suspect quickly taps on their mobile.
“We’re in their WhatsApp groups – they’ll be telling thousands now that we’re here… so our cover is blown,” the lead immigration officer tells me.
“It’s like a constant game of cat and mouse.”
Twelve Immigration Enforcement officers, part of the Home Office, are joining colleagues from Avon and Somerset Police in a crackdown on road offences and migrants working illegally.
The West of England and Wales has seen the highest number of arrests over the last year for illegal workers outside of London.
“It is a problem… we’re tackling it,” Murad Mohammed, from Immigration Enforcement, says. He covers all the devolved nations.
“This is just one of the operations going on around the country, every day of the week, every month of the year.”
Image: Murad Mohammed, from Immigration Enforcement, says his team are attempting to tackle the issue
Just outside the Cabot Circus shopping complex, we stop a young Albanian man who arrived in the UK on the back of a truck.
He’s on an expensive and fast-looking e-bike, with a new-looking Just Eat delivery bag.
He says he just uses it for “groceries” – but the officer isn’t buying it. He’s arrested, but then bailed instantly.
We don’t know the specifics of his case, but one officer tells me this suspected offence won’t count against his asylum claim.
Such is the scale of the problem – the backlog, loopholes and the complexity of cases – that trying to keep on top of it feels impossible.
This is one of many raids happening across the UK as part of what the government says is a “blitz” targeting illegal working hotspots.
Angela Eagle, the border security and asylum minister, joins the team for an hour at one of Bristol’sretail parks, scattered with fast food chains and, therefore, delivery bikes.
Image: Border security and asylum minister, Angela Eagle, speaks to Sky News
She says arrests for illegal working are up over the last year by 51% from the year before, to more than 7,000.
“If we find you working, you can lose access to the hotel or the support you have [been] given under false pretences,” she said.
“We are cracking down on that abuse, and we intend to keep doing so.”
There are reports that asylum seekers can rent legitimate delivery-driver accounts within hours of arriving in the country – skipping employment legality checks.
Uber Eats, Deliveroo, and Just Eat all told Sky News they’re continuing to strengthen the technology they use to remove anyone working illegally.
But a new Border Security Bill, working its way through Parliament, could see companies fined £60,000 for each illegal worker discovered, director disqualifications and potential prison sentences of up to five years.
“I had them all in to see me last week and I told them in no uncertain terms that we take a very tough line on this kind of abuse and they’ve got to change their systems so they can drive it out and off their platforms,” the minister tells me.
For some of those who arrive, a bike and a phone provide a way to repay debts to gang masters.
There were eight arrests today in Bristol, one or two taken into custody, but it was 12 hours of hard work by a dozen immigration officers and the support of the police.
As two mopeds are pushed onto a low-loader, you can’t help but feel, despite the best intentions, that at the moment, this is a losing battle.