A baby girl has become the first child in the UK to be born from a womb transplant.
Grace Davidson, who received the transplant in 2023, said the birth of her daughter Amy Isabel was the “greatest gift we could ever have asked for”.
The 36-year-old, from north London, received the donated womb from her older sister, Amy.
It was the first time the procedure had taken place in the UK, and the birth will give hope to thousands of women born without a womb – like those with Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome – or whose womb fails to function.
Image: Grace and Angus Davidson with the hospital team at the birth of baby Amy. Pic: Womb Transplant UK/PA
Amy Isabel was named after her aunt, and a surgeon who helped perfect the technique, and was born by planned caesarean section on 27 February at Queen Charlotte’s and Chelsea Hospital in London.
Mrs Davidson, an NHS dietitian, said she felt “shock” when she first held her daughter, adding: “We have been given the greatest gift we could ever have asked for.
“It was just hard to believe she was real. I knew she was ours, but it’s just hard to believe.
“It sort of feels like there’s a completeness now where there maybe wasn’t before.”
Image: Aunt Amy Purdie (right) with the happy family. Pic: Womb Transplant UK/PA
Her husband Angus, 37, said: “The moment we saw her was incredible, and both of us just broke down in emotional tears – it’s hard to describe, it was elation.
“It had been such a long wait. We’d been intending to have a family somehow since we were married, and we’ve kind of been on this journey for such a long time.”
Womb transplantation is on the way to becoming an acceptable, life-giving procedure
The birth of Amy Isabel is not just a first for the UK, but an important step towards womb transplantation becoming an established medical procedure.
It was little more than a decade ago that the world’s first baby was born following a womb transplant in Sweden.
And not without eyebrows being raised by some in the world of medical ethics.
Not all womb transplants, whether from a living relative or from a deceased donor, are successful. And not all result in successful or uncomplicated pregnancies.
But the surgical team behind this UK success have achieved a one-for-one: a healthy baby born from the first womb transplant ever performed here.
Amy Isabel joins an estimated 50 other babies and children worldwide now born via a womb transplant.
And she won’t be the last.
Around 100 women in at least 10 countries have undergone the procedure – three transplants have taken place in the UK since Amy’s mother became the first in 2023.
A study of 33 womb transplants in the US found 74% of the transplants remained healthy after a year and 80% of those resulted in a successful birth.
But a womb transplant is unlikely to ever become “routine”.
While the number of eligible women – those lacking a functioning uterus but having healthy ovaries – might number in the low thousands in a country the size of the UK, not all would meet the strict medical criteria needed to maximise the chance of a successful transplant and subsequent birth.
And not all might choose it.
A successful birth following a womb transplant involves three major operations. The first to receive the transplanted womb, a caesarean section to deliver the baby, then a hysterectomy to remove the womb once the recipient mother decides to have no more children.
Given a womb transplant isn’t “life-saving”, ethics guidelines require the procedure to be temporary. The long-term risks of organ rejection, and the drugs needed to prevent it, are considered too great once the womb has served its miraculous function.
Some medical ethicists still question the procedure as a whole, arguing it is unnecessarily risky for both the mother and baby, especially babies are born seriously pre-term and at low birth weight.
However, this latest success, and the increasing number of healthy babies born via the procedure worldwide may change that.
Womb transplantation is on the way to becoming an acceptable, life-giving procedure for women who previously had no hope of carrying a baby of their own.
Mrs Davidson was born with Mayer-Rokitansky-Kuster-Hauser, a rare condition that affects around one in every 5,000 women. It means they have an underdeveloped or missing womb.
Image: Grace with her sister Amy (right) and daughter. Pic: Womb Transplant UK/PA
However, the ovaries are intact and still function to produce eggs and female hormones, making conceiving via fertility treatment a possibility.
Before receiving the donated womb, Mrs Davidson and her husband underwent fertility treatment to create seven embryos, which were frozen for In Vitro Fertilisation (IVF) in central London.
Mrs Davidson had surgery in February 2023 to receive the womb from her 42-year-old sister Amy Purdie, who is a mother to two girls aged 10 and six.
Several months later, one of the stored embryos was transferred via IVF to Mrs Davidson.
The baby weighed 4.5lbs and was delivered several weeks early to ensure a safe, hospital-based delivery.
Ms Purdie called the birth of her niece “worth every moment”.
Professor Richard Smith and Isabel Quiroga were the lead surgeons for the womb transplant and both were in the operating theatre when Amy was delivered, with her parents choosing her middle name in honour of Ms Quiroga.
Prof Smith, clinical lead at the charity Womb Transplant UK and consultant gynaecological surgeon at Imperial College Healthcare NHS Trust, told Sky News that being in the operating theatre when Amy was delivered was “really quite remarkable”.
The medic said: “We’ve waited a very, very long time for this, and there’s been quite a lot of tears shed. Ironically the scariest bit of the day for me was when [Amy’s] mum and dad asked me to hold their baby, which was incredible.”
Ms Quiroga, consultant surgeon at the Oxford Transplant Centre, part of Oxford University Hospitals, told Sky News it was “quite a complex procedure” and “the pressure was immense when we did the transplant”.
But she said it was “totally amazing to see all that effort” and it has “been totally worth it”.
A father has told Sky News how his partner was driven over, and his baby son was flung 15ft in his pram, after they were hit by a vehicle during the Liverpool parade collision.
Daniel Everson, 36, had been with Sheree Aldridge and their five-month-old baby, Teddy, at Liverpool FC’s victory parade on Monday.
“The best day of my life turned into worst”, said Daniel, a lifelong fan of ‘The Reds’.
Daniel described the moment the car came towards him and his family.
“I tried to hold on to the front of the car and try and stop it, push it, do whatever I could [to stop it] from hitting my partner and my baby.
Image: Daniel Everson was in the crowd for the Liverpool trophy parade when the incident took place
“Me and my partner were flat on the roof, on the bonnet… we were just both trying to hold on for dear life with Ted next to us.
“And my partner went under the wheels of the car, of the front of the car, and it rolled over her leg, and I just bounced off to the side, but my boy and his pram got bounced totally in the opposite direction – about 15ft down the road.
“As soon as that happened, I just started screaming for my partner, and I found her and I asked where Teddy was, and she didn’t know… and I found him and he was okay, thank God.
“He was in the road, in his pram, on his back, and I grabbed him. I chucked the pushchair to the side and I ran up to some paramedics with him.”
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The suspect is being held on suspicion of attempted murder, dangerous driving and drug driving.
Daniel, from Telford, said he felt like he was in “hell” as he rushed back to find Sheree.
“I had to carry her up the road with four police officers holding her while she was screaming and crying. At that point, I didn’t know what was wrong with her, but I could see the injuries to her leg,” he explained.
Sheree, 36, is recovering at Aintree University Hospital after suffering muscle tissue damage. Daniel has been allowed to return home with Teddy after he was assessed at Alder Hey Children’s Hospital.
“I feel a lot of emotions right now. Upset, angry, traumatised. A lot of unanswered questions that need to be answered.
“To me, it just wasn’t handled properly – the situation with the car getting that far into the crowd, in my opinion, he should not have got anywhere near us.”
Merseyside Police have now been given more time to question a 53-year-old arrested after a car struck a crowd at Liverpool FC’s victory parade on Monday.
The suspect, who police have described as a white British man from the local area, is being held on suspicion of attempted murder, dangerous driving, and drug driving.
Police have said the extra time they have been given to question the suspect runs into Thursday.
Andrew Tate and his brother Tristan Tate have been charged with rape and other offences in the UK.
Andrew Tate, 38, faces 10 charges, including rape, actual bodily harm, human trafficking and controlling prostitution for gain, relating to three women.
His brother Tristan Tate, 36, faces 11 charges relating to one woman – including rape, actual bodily harm and human trafficking.
The charges were authorised in January 2024, but full details have only been released now.
Bedfordshire Police issued an international arrest warrant for the brothers over allegations, which they “unequivocally deny”, said to have occurred between 2012 and 2015.
The Tate brothers are facing separate allegations of trafficking minors, sexual intercourse with a minor and money laundering in Romania.
They are also accused of human trafficking and forming a criminal gang to sexually exploit women in a different case, which has been sent back to prosecutors.
They are due to be extradited to the UK following the conclusion of proceedings in Romania.
Image: Andrew Tate and his brother Tristan outside a Bucharest court in January. File pic: Inquam Photos/Octav Ganea via Reuters
A Crown Prosecution Service (CPS) spokesperson said: “We can confirm that we have authorised charges against Andrew and Tristan Tate for offences including rape, human trafficking, controlling prostitution and actual bodily harm against three women.
“These charging decisions followed receipt of a file of evidence from Bedfordshire Police.
“A European Arrest Warrant was issued in England in 2024, and as a result the Romanian courts ordered the extradition to the UK of Andrew and Tristan Tate.”
The spokesperson added: “However, the domestic criminal matters in Romania must be settled first.
“The Crown Prosecution Service reminds everyone that criminal proceedings are active, and the defendants have the right to a fair trial.
“It is extremely important that there be no reporting, commentary or sharing of information online which could in any way prejudice these proceedings.”
Representatives for Andrew Tate have been contacted by Sky News for comment.
Lawyer Matt Jury, of McCue Jury & Partners, representing several alleged British victims of Andrew Tate, said: “We welcome the clarity from the Crown Prosecution Service that our authorities are working to ensure the Tates face justice here in the UK – they cannot be allowed to escape extradition.
“At the same time, we ask once more that CPS admit its mistake in failing to prosecute Tate when he lived in the UK and finally charge him for the rape and assault of the other three women, our clients, who originally filed criminal complaints against him as long ago as 2014 but were failed by the system.
“They deserve justice, too.”
The allegations were subject to a police investigation, which was closed in 2019.
Merseyside Police has been given more time to question a 53-year-old man arrested over the Liverpool parade collision.
The suspect is being held on suspicion of attempted murder, dangerous driving and drug driving after a car was driven into a crowd at Liverpool FC’s victory parade on Monday.
Police have said the extra time they have been given to question the suspect runs into Thursday.
The force believes the vehicle which struck pedestrians on Water Street had followed an ambulance crew that was attending to someone suffering a heart attack, after a road block was temporarily lifted.
Earlier, new footage emerged showing a car being driven into the crowd as panicked fans watched in horror and tried to avoid being hit.
The CCTV footage showed supporters attempting to move out of the way as the vehicle ploughed into supporters.
Cries could be heard from the crowd – before police and members of the public chased after the car.
In an update on Wednesday, Merseyside Police said it was in contact with 79 people who were injured in the crash – an increase on the 65 people who were confirmed injured in the force’s previous update.
Seven people remain in hospital in a stable condition following the collision, the force added.
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Moment car drives into crowds in Liverpool
Detective Superintendent Rachel Wilson said: “I’m pleased to say that the number of people in hospital is reducing as they continue to recover from the awful incident.
“We continue to support those still receiving treatment and as part of our ongoing enquiries we are identifying more people who were injured.
“I want to reassure the public of Merseyside that detectives are making significant progress as we seek to establish the full circumstances that led to what happened.”
Image: Water Street where the collision happened has reopened. Pic: Reuters
Image: Pic: Reuters
DS Wilson said that “extensive CCTV enquiries” were being carried out across Liverpool to “establish the movements of the car, a Ford Galaxy, before the incident took place”.
She added: “We have already had an incredible response from many of those who were there on the day, and I thank them for their co-operation with our investigation.
“I would encourage anyone who has not yet contacted police who may have information on this incident to do so.
“An extensive investigation into the precise circumstances of the incident is ongoing, and we continue to ask people not to speculate on the circumstances surrounding the incident and refrain from sharing distressing content online.”
Image: Emergency service on Water Street after the collision. Pic: Reuters
It comes after Water Street was reopened to vehicles and pedestrians on Wednesday after the police cordon was lifted.
Street cleaning teams worked overnight to clear the road, which had been littered with bottles, cans and football scarves and flags.
One remaining Liverpool flag was removed from the top of a set of traffic lights by a worker wearing hi-vis.
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On Tuesday night, Liverpool manager Arne Slot decided not to attend the League Managers Association’s annual awards ceremony “in solidarity with those affected by the incident on Monday”.
Meanwhile, speaking at an awards ceremony on Tuesday, former Liverpool boss Jurgen Klopp said the collision on Water Street “showed the two faces of life”.
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Klopp sends ‘thoughts and prayers’ to victims
He said: “The most beautiful face for a long, long time: the parade was incredible, the mood was incredible and from one second to another everything changed and we learned again there are more serious things in the world than football.
“Thoughts and prayers go to the injured people and their families as well.
“It should have been one of the greatest days in the history of the city, after a long, long time, because we didn’t have the opportunity to do it last time. I don’t know how and why it happened but we know what happened and that’s very bad.”