Specialty pharmacies and online companies that have been selling off-brand copies of two blockbuster drugs for obesity and diabetes will need to phase out their versions next year under a federal decision issued Thursday.
The Food and Drug Administration said that a nationwide shortage of Eli Lillys Zepbound and Mounjaro has been resolved, eliminating the need for copycat versions of the drugs that have become wildly popular with Americans trying to lose weight.
The decision is a win for Lilly which had been pressing the FDA to take the step for months and is expected to impact how patients access the drugs, including how much they pay.
Zepbound is FDA-approved to treat obesity and Mounjaro is approved for diabetes.
They use the same active ingredient, tirzepatide.
The FDA said Thursday that Lillys supply is currently meeting or exceeding demand, after two years of shortages.
Both drugs are part of the GLP-1 class that has shown unprecedented results for helping people shed weight by decreasing appetite and boosting feelings of fullness.
Wegovy and Ozempic competing drugs from Novo Nordisk remain on the FDAs shortage list.
With demand for GLP-1 drugs booming, compounding pharmacies and telehealth companies like Hims and Ro have jumped into the market, selling cheaper versions online.
People can usually get a months supply for several hundred dollars.
Thursdays decision gives businesses between 60 and 90 days, depending on their size, to phase out their products.
The FDA permits compounded versions of brand name drugs when they are in shortage, and the shift back to Lillys medications could improve safety for consumers.
The FDA warned patients last year about problems with the ingredients and formulations of some GLP-1 drugs sold online.
The agency has limited oversight of compounding pharmacies, which are primarily overseen by state authorities.
Compounding pharmacies use raw drug ingredients to produce customized versions of prescription medications for instance, when patients have allergies to certain ingredients.
The industry has grown into a multibillion-dollar business over the past decade amid increasing drug shortages.
Demand for off-brand GLP-1 drugs has been amplified by aggressive online promotions from telehealth companies, which arent subject to the same marketing rules as drugmakers.
The FDA previously declared an end to the shortage of Mounjaro and Zepbound in early October, but reversed its decision after public pushback and a lawsuit filed by compounding pharmacies.
Review: Ride1Up’s Revv1 DRT e-bike is a rugged off-roader with plenty of suspension and hidden punch
When it comes to e-bikes, most people’s immediate thought is a commuter model designed to get you through streets to your various destinations, but with Ride1Up’s Revv1 DRT e-bike, the fun is extended (and primarily focused) to off-road adventures, and boy, does this baby have some go in it. It’s been over two years since we reviewed the Revv1 FS counterpart, which we came away quite impressed with its SUPER73-like design. Now we’re heading off the beaten path with this newer off-road variant, which boasts improved specs that outshine its predecessors in the series.
To get our full hands-on impression of this new flagship e-scooter, be sure to check out our review here.
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Heybike’s Prime Fall Sale drops the ALPHA all-terrain mid-drive e-bike to a new $1,399 low, more from $899
Heybike has launched its Prime Fall e-bike Sale with up to $700 in savings on a selection of the brand’s e-bikes, including several new and returning low prices. One such model that’s really benefiting is the ALPHA All-Terrain Mid-Drive e-bike that is down at $1,399 shipped. While this model normally carries a $1,699 MSRP, we more often see it keeping down at $1,599, and more recently $1,499 with regular sales and discounts outside of events. During this two-week event, however, you can save more on it than we’ve seen before, as the $300 markdown is dropping costs to a new all-time low. What’s more, there’s a bit of extra savings in the form of the FREE front cargo basket you’ll be getting. Head below for more on this model and the others seeing discounts right now.
The Heybike ALPHA e-bike is the first to be equipped with the brand’s newer 500W Mivice mid-drive motor (which is rated for 900 to 1000W peaks), bringing some serious balance and power to all terrain types. There’s also the 680Wh battery that powers the system, providing up to 60 miles of pedal-assisted travel – supported by a torque sensor – and yes, there is a throttle for when you want to do some electric cruising. Speeds max out at 28 MPH for those living in states where it’s allowed, while otherwise delivering a 20 MPH default top speed.
What’s really nice is that the mid-drive motor doesn’t seem to send the ALPHA all-terrain e-bike into heavier weight classes, as it retains a manageable 72 pounds in all, and there’s a 400-pound rider payload, so more people of larger builds can enjoy the fun. As a more cost-effective mid-drive model, there’s a nice array of features, including the hydraulic disc brakes, hydraulic front suspension fork, and 4-inch puncture-protected fat tires – all providing plenty of support when heading off-road. There’s also an 8-speed Shimano Altus derailleur, an integrated rear cargo rack (and don’t forget the free front cargo basket), an auto-on headlight, a brake-activated taillight, and LCD screen for your setting adjustments, and more.
Get up to 50A charging speeds with Autel’s MaxiCharger AC Lite level 2 EV station at $455
By way of its official Amazon storefront, Autel is returning its MaxiCharger AC Lite Home 50A Level 2 EV Charging Station back to $455.20 shipped, which beats out the brand’s direct website, where it is listed for its full $569 rate. This is the first time since late July that this model has seen a discount, with the rate here only beaten in 2025 by a drop to $450 during July’s Prime Day event, and a fall further to its $399 low that hasn’t been seen since Black Friday sales. You’re looking at a 20% markdown here that cuts $114 off the going rate for the second-best price of the year and the third-lowest overall.
Lectric restocks popular XPedition 2.0 cargo e-bikes with up to $674 in FREE bundled gear starting from $1,399
After selling out during some of the past sales, Lectric has officially restocked its XPedition 2.0 Cargo e-bikes, with them getting up to $674 in FREE bundled gear. While supplies are replenished and last, you can pick up the base 13Ah single-battery model with a $326 bundle at $1,399 shipped, while the 26Ah dual-battery model with a $525 bundle is at $1,799 shipped, and the 35Ah dual-battery model with the largest $674 bundle is at $1,999 shipped. As is the norm with Lectric, the discounts are on the bundles of free gear rather than the more rare direct price cuts to costs, and these packages are mostly focused on adding comfort for passengers – perfect for parents needing a new way to shepherd kids to and from daily appointments, which is what I’ve seen it mainly used for in NYC. Head below for more on the free gear you’ll be getting, as well as a rundown on the e-bike’s performance.
Husqvarna’s Automower 115H 4G robot with a built-in alarm system returns to its second-best $499 price
Amazon is offering the Husqvarna Automower 115H 4G Robotic Lawn Mower at $499 shipped, beating out the brand’s direct website, where it is currently priced for its full $700 MSRP. At Amazon, though, you’ll more regularly find it at $599 since June, with the discounts we’ve seen this year having been dropping costs lowest to either $499 or $490. The deal we’re seeing today gives you a 29% markdown off the MSRP, saving you $201 ($100 off the going Amazon rate) and landing it back at the second-best price.
The savings this week are also continuing to a collection of other markdowns. To the same tune as the offers above, these all help you take a more energy-conscious approach to your routine. Winter means you can lock in even better off-season price cuts on electric tools for the lawn while saving on EVs and tons of other gear.
New Orleans will host the 2028 College Football Playoff National Championship at Caesars Superdome, the CFP announced Wednesday.
The 14th title game in the CFP era will be played Monday, Jan. 24, 2028, following the 2027 regular season and playoff rounds. New Orleans will become the third city to host the CFP title game for a second time. The game has also been to Atlanta twice (2018, 2025) and will make its second appearance (along with 2021) in South Florida this season Jan. 19 at Hard Rock Stadium in Miami Gardens.
“The College Football Playoff is thrilled to bring the national championship game back to New Orleans in 2028,” CFP executive director Rich Clark said in a statement. “Few cities embrace college football quite like New Orleans, with its unmatched hospitality, culture and passion for the game. We know fans, teams and the entire college football community will have an unforgettable experience in one of the sport’s most iconic destinations.”
The 2027 title game is set for Allegiant Stadium in Las Vegas.
AMES, Iowa — No. 14 Iowa State‘s secondary will be without longtime starters Jontez Williams and Jeremiah Cooper for the rest of the season because of knee injuries.
Coach Matt Campbell announced Tuesday that Williams damaged the ACL in his right knee late in the Cyclones’ 39-14 win over Arizona on Saturday. Cooper tore his ACL in practice last week. The two have combined for 55 starts.
Williams, an Associated Press All-Big 12 second-team pick in 2024, had one interception and two pass breakups this season. He was hurt with three minutes left against Arizona as he dove in an attempt to knock a ball away from a receiver.
“So that’s a situation that really stinks for the kid,” Campbell said. “But man, just how he’s handled it has been uber impressive. And a great human. He’ll be back ready to rock and roll next year.”
Cooper has made 36 starts since 2022 and was an AP All-Big 12 first-team pick at safety in 2023. He switched to cornerback full time this season and had an interception and three pass breakups through four games.
Tre Bell, a transfer from Lindenwood, made his first start for the Cyclones in Cooper’s place against Arizona. Quentin Taylor Jr., who played 26 snaps against Arizona, would be in line to make his first start when the Cyclones (5-0, 2-0 Big 12) visit Cincinnati (3-1, 1-0) on Saturday.