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The physiology of laughter: What happens in our bodies when we laugh?
Laughter's Magic: The neurochemistry of a good chuckle
Giggles and gains: Physical health benefits from abdominal workouts to immune boosting
Laughter in Therapy: Techniques, applications, and transformative tales
Conclusion
Further reading and references

A ubiquitous characteristic found in all humans is the ability to laugh, no matter what culture or race, this seems to be a common denominator that connects everyone. While laughing is an attribute of happiness and joy, it also has significant health implications that benefits the individual, from reducing stress levels to boosting the immune system as well as aiding with physical health. This article will delve into the various health advantages of engaging in laughter.

Image Credit: fizkes/Shutterstock.com The physiology of laughter: What happens in our bodies when we laugh?

Laughter has been found to start from infancy between the second and sixth month of newborn life and is one of the first social vocalizations in humans, with spontaneous laughter even being seen in children born as deaf or blind disabilities.  

Interestingly, this instinctive behavior that we’re genetically programmed to display, has also been found in non-human primates.

The mechanism of laughter is produced through the cooperation of various systems that work to create an expressive pattern through respiratory, facial, bodily, acoustic and cognitive alterations.

There are two different types of laughter found in humans, including involuntary emotionally-driven laughter, which is reliant on a positive emotional state, and voluntary laughter that represents the intentional reproduction of emotional laughter. 

The natural maneuver caused by laughter is stimulated by emotion, and during laughter, stress is applied to the chest wall, which causes fast and significant motion. This can lead to sudden and substantial reduction in lung volume in all respiratory compartments as well as compression of the airways.

Laughter can also impact the brain in various ways. The activation of the hypothalamic-pituitary-adrenocortical (HPA) axis and the subsequent increase in glucocorticoids is a significant physiological response to either physical or psychological stress signals. There are previous findings within adults that have suggested spontaneous laughter can affect the HPA axis through the reduction of cortisol levels, which can decrease stress. Laughter's Magic: The neurochemistry of a good chuckle

The two types of laughter cause variation in facial expressions as well as stimulating different neural pathways that control them.

Duchenne laughter, known as involuntary laughter, begins in the brain stem and limbic system, which is responsible for emotions. However, non-Duchenne laughter can be controlled by voluntary premotor regions, which is thought to contribute to planning movements, found in the frontal cortex.

A study from The Journal of Neuroscience has found social laughter to increase pleasurable sensations as well as triggering endogenous opioid release in the brain. Participants have also been found to have increased pain thresholds after watching comedy in order to induce laughter.

The increase of the brain’s production of endorphins, known as feel-good chemicals, caused by laughter, have the ability to relieve pain and decrease stress levels. The benefits of laughing | News2Me Play Giggles and gains: Physical health benefits from abdominal workouts to immune boosting

As well as reducing stress levels, laughter can also impact heart rate and blood pressure, which can help with relaxation.

Psychologist, Susan Albers, explained how humor can impact immunity in positive ways, stating, “Laughter helps to boost the immune system, which makes you more resistant to disease. Also, it decreases stress hormones, which are taxing to your immune system. On the other hand, laughter increases the antibody-producing cells and T cells in our bodies. These cells are like a defense army against illness.”

She continues with providing one of the best reasons for laughter, which is to prevent emotional eating, “when we laugh, it triggers the release of feel-good neurotransmitters. Even a subtle smile can trick your brain into thinking you are happy – thus reducing the need to munch to soothe your nerves or anxiety.” With depression becoming an epidemic in modern society, laughter can aid in improving low moods and reducing stress, even if its artificially induced.

The physical benefit of laughter is also extensive, with this joyous experience also providing a workout for bodily systems, including the cardiovascular, pulmonary and respiratory systems. Laughter causes the diaphragm, chest and abdominal muscles to tighten, driving the lungs to work harder through forcing the remaining air out and permitting fresh air deeper into the lungs, which can enable more effective exhalations, due to assisting the expansion of the alveoli.

Additionally, laughter shares common advantages that are associated with exercise, with a recent literature review confirming the physiological benefits of laughter, such as through exercising and relaxing muscles as well as improving respiration and stimulating circulation.

Simulated laughter may be ideal for the older population with functional or cognitive impairments that can access benefits of laughter more easily, with sedentary individuals being able to use laughter as part of a cardiovascular exercise program.

Interestingly, the physical act of laughter can be compared to mild cardiovascular exercise, and intense laughter through laughter exercises can be equivalent to short aerobic bursts in interval training, a type of exercise with varied intensity popular in abdominal workouts.

Image Credit: Motortion Films/Shutterstock.com Laughter in Therapy: Techniques, applications, and transformative tales

The phrase, ‘laughter is medicine’, has often been propagated through communities due to its ability to engage both the mental and physical body effectively. Laughter therapy is a type of cognitive behavioral therapy that aims to drive healthy relationships relating to physical, psychological and social wellbeing, and ultimately improves quality of life of individuals.

Laughter serves a social function and can act as a signal for a connection with another person. Research has found we are 30 times more likely to laugh within a group, or even with one other person, aiding in friendship, feelings of happiness as well as decreasing stress due to the rush of endorphins. Conclusion

Laughter has been reinforced by recent research linking various positive benefits, from physical advantages to increased pain tolerance, immune boosting impact, as well as aiding with diverse medical ailments, such as in oncology, psychiatry and rehabilitation.

With a more holistic view of medicine, functional medicine has increased in popularity, and laughter may be a natural medicinal supplement to improve the overall health of populations. Further reading and references Cleveland Clinic. It’s OK to laugh right now. Cleveland Clinic. November 27, 2023. Accessed December 1, 2023. https://health.clevelandclinic.org/its-ok-to-laugh-right-now. Greene CM, Morgan JC, Traywick LS, Mingo CA. Evaluation of a laughter-based exercise program on health and self-efficacy for exercise. The Gerontologist. Published online 2016. doi:10.1093/geront/gnw105 Is laughter good for lung health? American Lung Association. Accessed December 1, 2023. https://www.lung.org/blog/laughter-for-lungs. Kramer CK, Leitao CB. Laughter as medicine: A systematic review and meta-analysis of interventional studies evaluating the impact of spontaneous laughter on cortisol levels. PLOS ONE. 2023;18(5). doi:10.1371/journal.pone.0286260 Manninen S, Tuominen L, Dunbar RI, et al. Social laughter triggers endogenous opioid release in humans. The Journal of Neuroscience. 2017;37(25):6125-6131. doi:10.1523/jneurosci.0688-16.2017 Sabato G. What’s so funny? the science of why we laugh. Scientific American. August 13, 2019. Accessed December 1, 2023. https://www.scientificamerican.com/article/whats-so-funny-the-science-of-why-we-laugh/. Stierwalt EES. Why do we laugh? Scientific American. February 14, 2020. Accessed December 1, 2023. https://www.scientificamerican.com/article/why-do-we-laugh/. Stress relief from laughter? it’s no joke. Mayo Clinic. September 22, 2023. Accessed December 1, 2023. https://www.mayoclinic.org/healthy-lifestyle/stress-management/in-depth/stress-relief/art-20044456. Talami F, Vaudano AE, Meletti S. Motor and limbic system contribution to emotional laughter across the lifespan. Cerebral Cortex. 2019;30(5):3381-3391. doi:10.1093/cercor/bhz316 Yim J. Therapeutic benefits of laughter in mental health: A theoretical review. The Tohoku Journal of Experimental Medicine. 2016;239(3):243-249. doi:10.1620/tjem.239.243

Last Updated: Dec 11, 2023

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US

Sean ‘Diddy’ Combs denied bail after being convicted over prostitution-related offences

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Sean 'Diddy' Combs denied bail after being convicted over prostitution-related offences

Sean “Diddy” Combs has been found guilty of transportation for prostitution following a landmark trial in New York – but cleared of more serious charges of sex trafficking and racketeering conspiracy.

The hip-hop mogul was accused by prosecutors of abusing and coercing three alleged victims, including his former long-term partner, singer and model Cassie Ventura, and other crimes including kidnapping, arson and blackmail.

Jurors decided not all the allegations were proven – but Combs still faces several years in prison after being convicted of transporting people across the US, including Cassie and another former girlfriend “Jane”, and paying male escorts to engage in sexual encounters.

However, with the not guilty verdict on three other more serious charges – racketeering conspiracy and two of sex trafficking – the 55-year-old has avoided a maximum possible sentence of life behind bars.

Despite a request by his defence team, he was denied bail ahead of sentencing – which has been scheduled for Friday 3 October.

Sean "Diddy" Combs reacts after verdicts are read of the five counts against him, during Combs' sex trafficking trial in New York City, New
Image:
Combs appeared upbeat in court as the verdict was announced. Pic: Jane Rosenberg/ Reuters

Marc Agnifilo, part of Diddy’s defence team, described the ruling as “a victory of all victories”.

Outside the courthouse, he said the jury “got the situation right, or certainly right enough”.

Another of his lawyers, Nicole Westmoreland, said: “He actually battled for his freedom, for his innocence, and he did it.

“And, you know, a lot of times, people are too afraid to do it. Today is a major win to show what the system can do.”

The mixed result from the jury came not long into their third day of deliberations. In the courtroom in Manhattan, there were cheers from Combs’s family – and the rapper himself held his hands up in a prayer motion, looking at the jury, and hugged his defence lawyer Teny Geragos.

His mood seemed very different to just a day earlier – when he learned the jury had reached a verdict on four of the five charges, but were split on the racketeering charge.

After deliberating for longer on Wednesday, they came to a unanimous decision.

As the verdict sunk in, Combs appeared overwhelmed, kneeling at his chair and bowing his head in prayer once again.

“I’ll be home soon,” he said as he faced his family members. “I love you, Mum.”

Sean "Diddy" Combs reacts after verdicts are read of the five counts against him, during Combs' sex trafficking trial in New York City, New
Image:
Combs later seemed to become overwhelmed with relief. Pic: Jane Rosenberg/ Reuters

The application for bail

Combs’s defence team argued that as he had been cleared of the most serious charges, he should be bailed ahead of sentencing.

His lawyer Marc Agnifilo said he had been a model prisoner and added: “He’s not going to flee. He’s been given his life back.”

But prosecutor Maurene Comey argued Combs had a history of violence, which Judge Arub Subramanian agreed with. “At trial, the defence conceded the defendant’s violence in his personal relationships,” he said.

After being denied bail, Combs attempted get the judge’s attention – but after consulting with Mr Agnifilo, he did not speak.

Sean "Diddy" Combs watches as his former girlfriend Casandra "Cassie" Ventura is sworn in as a prosecution witness before U.S. District Judge Arun Subramanian at Combs' sex trafficking trial in New York City, New York, U.S., May 13, 2025 in this courtroom sketch. REUTERS/Jane
Image:
Casandra ‘Cassie’ was heavily pregnant when she gave evidence at the start of the trial. Pic: Jane Rosenberg/ Reuters

Cassie ‘paved the way’

Reacting to the verdict, Cassie’s lawyer Douglas H Wigdor said that although jurors did not find Combs guilty of sex-trafficking Cassie, she had “paved the way” for the other guilty verdicts.

“By coming forward with her experience, Cassie has left an indelible mark on both the entertainment industry and the fight for justice,” he said.

“We must repeat – with no reservation – that we believe and support our client, who showed exemplary courage throughout this trial.”

Cassie, who testified heavily pregnant just three weeks before giving birth, displayed “unquestionable strength”, he added, and “brought attention to the realities of powerful men in our orbit”.

Videos of “freak off” sex sessions with male escorts were shown to jurors only during the seven-week trial, with the footage kept private from members of the public and media in court.

Read more:
How the trial unfolded
The rise and fall of Sean ‘Diddy’ Combs

Sean "Diddy" Combs listens as Assistant U.S. Attorney Meredith Foster questions Ananya Sankar during his sex trafficking trial
Image:
Pic: Reuters/ Jane Rosenberg

Former employees, along with escorts, hotel staff and police officers were among those to give evidence.

Cassie and Jane, who used a pseudonym, also testified. They told the court they were coerced into drug-fuelled “freak offs” – which were also referred to as “hotel nights” or “wild king nights” – with male escorts, and abused throughout their relationships.

Combs’s defence team presented a very different picture to show that sexual acts, including freak offs, were consensual.

They conceded the music star could be violent, had a bad temper and used drugs. He also had multiple relationships at the same time. But crucially, they said, while he was “not proud” of some of his behaviour, none of it made him guilty of the charges against him.

After hearing evidence of flights and travel for escorts and Cassie and Jane, paid for by Combs, as well as hotel bookings across the US and the Caribbean, jurors found him guilty of the transportation to engage in prostitution charges. However, they did not find that the allegations against the rapper amounted to sex trafficking or racketeering.

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CCTV footage shows Diddy ‘attacking’ Cassie in hotel

The Cassie hotel tape

Combs, known variously as Puff Daddy, P Diddy, and Diddy over the years, was once one of the most influential figures in hip-hop – famous as a producer, founder of Bad Boy Records and manager of the late Notorious BIG in the 1990s, as well as a rapper in his own right.

As an artist, he won three Grammys during his career, and had hits including I’ll Be Missing You, Come With Me, and Bad Boy For Life.

In September 2023, he received the “global icon” award from MTV and was given the key to New York City at a ceremony in Times Square, just a few miles away from the streets in Harlem where he spent his first years.

Allegations first came to prominence in November 2023, when Cassie filed a bombshell lawsuit accusing him of coercing her into unwanted sex sessions, as well as blackmail and several incidences of violence.

The suit was settled in 24 hours – for $20m, it emerged during the trial – but months later CNN aired hotel security footage showing Combs punching and kicking Cassie and throwing her to the floor in 2016.

He apologised after the video aired, saying: “I was disgusted when I did it.”

Footage from the hotel incident was shown during the trial.

Following the verdict, the rapper now awaits sentencing. He also still faces several civil lawsuits, most of which were filed in the wake of his arrest in September 2024.

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UK

Four charged after £7m of damage caused to aircraft at RAF Brize Norton

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Four charged after £7m of damage caused to aircraft at RAF Brize Norton

Four people have been charged after £7m of damage was caused to two Voyager aircraft at RAF Brize Norton.

The investigation into the incident early on Friday 20 June was led by counter-terror police.

They have been charged with conspiracy to enter a prohibited place knowingly for a purpose prejudicial to the safety or interests of the UK – and conspiracy to commit criminal damage.

Two Voyager aircraft at RAF Brize Norton were damaged. PA file pic
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Two Voyager aircraft at RAF Brize Norton were damaged. PA file pic

The four charged have been identified as:

• Amy Gardiner-Gibson, 29, of no fixed abode

• Daniel Jeronymides-Norie, 35, from London

• Jony Cink, 24, of no fixed abode

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• Lewie Chiaramello, 22, from London

They will appear at Westminster Magistrates’ Court later today.

Brize Norton

A 41-year-old woman arrested last week on suspicion of assisting an offender has been released on bail until 19 September.

Meanwhile, a 23-year-old man detained on Saturday was released without charge.

Last month’s incident at RAF Brize Norton in Oxfordshire was claimed by the activist group Palestine Action.

Yesterday, MPs voted to proscribe the group as a terrorist organisation.

The legislation passed with 385 MPs voting in favour, while 26 were against.

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Technology

Datadog stock jumps 10% on tech company’s inclusion in S&P 500 index

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Datadog stock jumps 10% on tech company’s inclusion in S&P 500 index

The Datadog stand is being displayed on day one of the AWS Summit Seoul 2024 at the COEX Convention and Exhibition Center in Seoul, South Korea, on May 16, 2024.

Chris Jung | Nurphoto | Getty Images

Datadog shares were up 10% in extended trading on Wednesday after S&P Global said the monitoring software provider will replace Juniper Networks in the S&P 500 U.S. stock index.

S&P Global is making the change effective before the beginning of trading on July 9, according to a statement.

Computer server maker Hewlett Packard Enterprise, also a constituent of the index, said earlier on Wednesday that it had completed its acquisition of Juniper, which makes data center networking hardware. HPE disclosed in a filing that it paid $13.4 billion to Juniper shareholders.

Over the weekend, the two companies reached a settlement with the U.S. Justice Department, which had sued in opposition to the deal. As part of the settlement, HPE agreed to divest its global Instant On campus and branch business.

While tech already makes up an outsized portion of the S&P 500, the index has has been continuously lifting its exposure as the industry expands into more areas of society.

DoorDash was the latest tech company to join during the last rebalancing in March. Cloud software vendor Workday was added in December, and that was preceded earlier in 2024 with the additions of Palantir, Dell, CrowdStrike, GoDaddy and Super Micro Computer.

Stocks often rally when they’re added to a major index, as fund managers need to rebalance their portfolios to reflect the changes.

New York-based Datadog went public in 2019. The company generated $24.6 million in net income on $761.6 million in revenue in the first quarter of 2025, according to a statement. Competitors include Cisco, which bought Splunk last year, as well as Elastic and cloud infrastructure providers such as Amazon and Microsoft.

Datadog has underperformed the broader tech sector so far this year. The stock was down 5.5% as of Wednesday’s close, while the Nasdaq was up 5.6%. Still, with a market cap of $46.6 billion, Datadog’s valuation is significantly higher than the median for that index.

— CNBC’s Ari Levy contributed to this report.

CNBC: Datadog CEO Olivier Pomel on the cloud computing outlook

Datadog CEO Olivier Pomel on the cloud computing outlook

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