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By Deliana Infante Reviewed by Lily Ramsey, LLM

The sweet debate
Exploring artificial options
Nature's sweetness
Sweetener safety and health
Beyond taste and health
Sweet decisions
References 
Further reading

Artificial and natural sweeteners are popular sugar substitutes. While artificial sweeteners promise zero calories, their health effects are controversial.

Natural sweeteners, such as honey and stevia, offer a healthier alternative but still require moderation. Ultimately, making informed dietary choices about sugar substitutes is critical to overall health and wellness.

Image Credit: Pheelings media/Shutterstock.com The sweet debate

Artificial sweeteners are chemically synthesized sugar substitutes designed to provide the sweetness of sugar without the calories and potential blood sugar spikes.1 Common examples include aspartame, sucralose, and saccharin, which are often found in "diet" or "zero-calorie" beverages and low-sugar processed foods.1

Natural alternatives, on the other hand, are sweeteners derived from natural sources, such as plants or fruits. They include stevia, honey, agave nectar, and more.1,2 Although these sweeteners contain calories, they often have a lower glycemic index than regular sugar, meaning they're less likely to spike blood sugar levels.1,2

The prevalence of these molecules in the modern diet is hard to ignore. Fueled by a global push toward healthier eating and weight management, their use has skyrocketed; the U.S. Food and Drug Administration (FDA) alone has approved six artificial sweeteners and designated several natural alternatives as "generally recognized as safe" (GRAS).3

In addition to providing a lower-calorie alternative to sugar, these sweeteners allow people with diabetes to enjoy sweet-tasting foods without disturbing their blood sugar levels.3 However, the health implications are still a topic of much debate, underscoring the need to make informed dietary choices. Exploring artificial options

Six artificial sugar substitutes have been approved by the FDA:

Saccharin (Sweet and Low, Sweet Twin, Sweet'N Low, and Necta Sweet), aspartame (Nutrasweet, Equal, and Sugar Twin), acesulfame potassium (Sunett and Sweet One), sucralose (Splenda), neotame (Newtame), and advantame (Advantame).3

They typically have a more complex chemical structure than regular sugar, as they are synthetically-made compounds that contain nitrogen, chlorine, and sulfur elements. The most common are aspartame and sucralose.1

Aspartame is known for its intense sweetness and low-calorie profile. It is made up of aspartic acid and phenylalanine.4 When metabolized, it breaks down into these amino acids and a small amount of methanol. Although it is up to 200 times sweeter than sugar, it provides zero calories.4

Sucralose is another high-intensity artificial sweetener that is about 600 times sweeter than sugar.1,4 It is chemically produced by sucrose chlorination. Sucralose remains stable under heat and over a wide range of pH conditions. That's why it's ideal for use in cooking or processed foods.1,4 These sweeteners underwent a rigorous approval process before they came to market.5

The FDA5 and the European Food Safety Authority (EFSA)6 take strict measures to ensure the safety of artificial sweeteners entering the market.5,6 The approval process begins when a manufacturer submits a detailed application for food ingredient approval, including scientific research and evidence to support the product's safety. 5,6

The agencies then review the evidence and compare the cumulative dietary exposure estimate with toxicological information on the sweeteners. 5,6 If the substance meets the standards, it is approved.  However, its safety continues to be monitored. 5,6

It's also important to remember that each sweetener has an Acceptable Daily Intake (ADI), an estimate of the amount of a substance a person can consume daily over a lifetime without health risks.4-6 Often, these limits far exceed the amounts people consume. 4-6 Difference Between Artificial Sweeteners And Real Sugar Play Nature's sweetness

In addition to their enhanced sweetness, natural sweeteners have a unique and rich nutritional profile.  Stevia, for example, is a zero-calorie sweetener derived from the leaves of Stevia rebaudiana, but its high-intensity sweetness doesn't affect blood sugar levels.4 Another example is Siraitia grosvenorii Swingle fruit extract, commonly known as monk fruit/luo han guo.4

Then there's thaumatin, a natural sweetener derived from the fruit of the West African katemfe fruit.4 It's estimated to be 2000 times sweeter than sugar but has a different flavor profile that includes lingering sweetness and delayed onset.4

In the case of honey and maple syrup, these two natural sweeteners are composed primarily of fructose and glucose and have a moderate effect on blood sugar levels, but have interesting antioxidant and antibacterial properties.7,8 Sweetener safety and health

Scientific evidence shows that the health effects of artificial sweeteners vary. Aspartame, for example, is metabolized to methanol, which at high levels can lead to toxic health effects and has been linked to the development of cancer.4,9 On the other hand, sucralose (Splenda) has been associated with gut permeability and changes in the microbiota, negative modulation of T-cell responses, inflammation, oxidative stress, and genotoxicity.9-11

The WHO's risk assessment of aspartame concluded that there was limited evidence to change the ADI previously established.12 In the case of sucralose and the rest of the sweeteners (natural and synthetic), the WHO recommended against their consumption for weight loss unless the individual suffers from pre-existing diabetes.13 Beyond taste and health

It is important to note that dietary choices about sweeteners can have an impact beyond health. The production of artificial sweeteners often involves complex, energy-intensive industrial processes that contribute to a larger carbon footprint.

They have also recently raised public concern for their potential negative impact on aquatic life, as they are resistant to wastewater treatment and remain as a new source of pollution in water bodies.14

On the other hand, natural sweeteners, such as honey, may have their own environmental and ethical implications, particularly concerning the welfare of bees. However, this calls for attention to the growing trend of sustainable and ethically sourced sweeteners.15 Locally produced honey, organic stevia, and maple syrup, for example, have less environmental impact and often support community economies and fair trade practices.15 Sweet decisions

When choosing between artificial sweeteners and natural alternatives, health goals and dietary needs must be considered. Artificial sweeteners are low in calories and may aid in weight management for individuals with certain health conditions or diseases such as diabetes, while natural sweeteners such as honey or maple syrup have different nutritional profiles and biological activities.

For diabetes management, artificial sweeteners may be preferred due to their minimal impact on blood glucose, while natural sweeteners should be used with caution. Moderation is key, as excessive consumption of either type can interfere with weight management and glycemic control. References Chattopadhyay S, et al.(2011). Artificial Sweeteners – a review. Journal of Food Science and Technology, 51(4), 611–621. https://doi.org/10.1007/s13197-011-0571-1 Commissioner, O. of the. (n.d.). How sweet it is: All about sweeteners. U.S. Food and Drug Administration. [Online]  https://www.fda.gov/consumers/consumer-updates/how-sweet-it-all-about-sweeteners Center for Food Safety and Applied Nutrition. (n.d.-b). High-intensity sweeteners. U.S. Food and Drug Administration. [Online]  https://www.fda.gov/food/food-additives-petitions/high-intensity-sweeteners Center for Food Safety and Applied Nutrition. (n.d.-a). Aspartame and other sweeteners in food. U.S. Food and Drug Administration.  [Online] https://www.fda.gov/food/food-additives-petitions/aspartame-and-other-sweeteners-food Center for Food Safety and Applied Nutrition. (n.d.-c). Understanding how FDA regulates food additives and Gras ingredients. U.S. Food and Drug Administration. [Online]  https://www.fda.gov/food/food-additives-and-gras-ingredients-information-consumers/understanding-how-fda-regulates-food-additives-and-gras-ingredients Food Additives. European Food Safety Authority. (n.d.). [Online]  https://www.efsa.europa.eu/en/topics/topic/food-additives Samarghandian S, et al. (2017). Honey and Health: A Review of Recent Clinical Research. Pharmacognosy Res. 9(2):121-127. doi: 10.4103/0974-8490.204647. PMID: 28539734; PMCID: PMC5424551. Mohammed F, et al.(2023). Nutritional, pharmacological, and sensory properties of Maple Syrup: A comprehensive review. Heliyon, 9(9). https://doi.org/10.1016/j.heliyon.2023.e19216 Artificial Sweeteners and cancer. National Cancer Institute. (n.d.). [Online]  https://www.cancer.gov/about-cancer/causes-prevention/risk/diet/artificial-sweeteners-fact-sheet#:~:text=Six%20artificial%20sweeteners%20are%20approved,sucralose%2C%20neotame%2C%20and%20advantame. Schiffman S.S, et al. (2023). Toxicological and pharmacokinetic properties of sucralose-6-acetate and its parent sucralose: in vitro screening assays. Journal of Toxicology and Environmental Health, Part B, 26(6), 307–341. https://doi.org/10.1080/10937404.2023.2213903 Zani F, et al. (2023). The dietary sweetener sucralose is a negative modulator of T cell-mediated responses. Nature, 615(7953), 705–711. https://doi.org/10.1038/s41586-023-05801-6 World Health Organization. (n.d.-a). Aspartame hazard and risk assessment results released. World Health Organization. [Online] https://www.who.int/news/item/14-07-2023-aspartame-hazard-and-risk-assessment-results-released World Health Organization. (n.d.-b). Who advises not to use non-sugar sweeteners for weight control in newly released guideline. World Health Organization. [Online]  https://www.who.int/news/item/15-05-2023-who-advises-not-to-use-non-sugar-sweeteners-for-weight-control-in-newly-released-guideline Naik A.Q, et al. (2021). Environmental impact of the presence, distribution, and use of artificial sweeteners as emerging sources of pollution. Journal of Environmental and Public Health, 2021, 1–11. https://doi.org/10.1155/2021/6624569 Choudhury, N. R. (2023, August 17). Are naturally derived sweeteners more sustainable?. Food Beverage Insider. [Online]  https://www.foodbeverageinsider.com/sweeteners/naturally-derived-sweeteners-sustainability-and-eco-friendliness Further reading What are the Effects of Artificial Sweeteners on Gut Health? Sucralose: Safety and Evidence Are Sweeteners Healthy?

Last Updated: Feb 16, 2024

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Child sexual exploitation victims ‘not in scope’ of violence against women and girls strategy

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Child sexual exploitation victims 'not in scope' of violence against women and girls strategy

Victims of child sexual exploitation are “not explicitly within the scope” of the Violence Against Women and Girls (VAWG) strategy being drafted by the government, Sky News can reveal.

Child Sexual Abuse and Exploitation (CSEA) is a form of child abuse, described by police as a “critical threat” to women and girls.

It includes crimes such as grooming, and can involve both physical contact, such as rape, or non-physical – like forcing children to look at sexual images.

Sky News has been shown an internal Home Office document presented to various stakeholders in the sector.

Screenshot detailing strategy
Image:
Screenshot detailing strategy

It’s titled “Scope of the Strategy… Our draft definition of VAWG”, and says that while it recognises “links” between VAWG and child sexual exploitation, it is not “explicitly within the scope of the strategy”.

“VAWG is Violence Against Women and Girls. If you take child sexual abuse out of it, where are the girls?” Poppy Eyre told Sky News.

Poppy was sexually abused and raped by her grandfather when she was four.

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It wasn’t until she was 11, after a PHSE lesson on abuse at school, that she understood the enormity of what had happened.

“I remember very vividly when the police came round and told me… this is what we’re charging him with,” said Poppy.

“We’re charging him with sexual abuse and rape. And I remember being like, I had no idea that’s what it was, but I know that’s really bad.”

Poppy Eyre was sexually abused and raped by her grandfather when she was four
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Poppy Eyre was sexually abused and raped by her grandfather when she was four

Poppy’s grandfather was convicted and died in prison.

She questions how authorities would police crime if child sexual abuse is excluded from an umbrella strategy to tackle violence against women and girls.

“Are they holding child sexual abuse at the same level of importance as they are with violence against women? You’d hope so, but potentially not, because it doesn’t need to be in the figures”, she said.

'Are they holding child sexual abuse at the same level of importance?' asks Poppy
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‘Are they holding child sexual abuse at the same level of importance?’ asks Poppy

The government has pledged to halve VAWG within a decade, by 2035.

“If the government are measuring themselves against halving violence against women and girls – if they’re not looking at the scale of child sexual abuse and child sexual exploitation within that – that will mean we are failing many young victims of abuse,” said Andrea Simon, director of campaign group End Violence Against Women.

The Centre of Expertise on Child Sexual Abuse, which is funded by the Home Office, estimates 500,000 children in England and Wales are sexually abused every year.

‘Danger’ of having separate plan

Rape Crisis told Sky News that “for any strategy to be effective” it “must include all forms of gender-based violence against all women and girls”, suggesting there is a “danger” in having a separate plan for child sexual abuse.

Its chief executive, Ciara Bergman, said it could create a “problematic and potentially very unhelpful” distinction between victims of domestic abuse, expected to be covered by the strategy, and child sexual abuse.

“Some perpetrators of domestic abuse also sexually abuse their children,” she told Sky News.

The government insists the strategy will include action to tackle child sexual abuse, but says it also plans to create a distinctive programme to address its specific crimes.

Poppy's mother Miranda Eyre says she's 'speechless' and 'angry' over the government's approach
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Poppy’s mother Miranda Eyre says she’s ‘speechless’ and ‘angry’ over the government’s approach

“Sexual abuse is violence against a child,” said Poppy’s mother, Miranda Eyre, who now works as a counsellor specialising in trauma.

“It is violence against girls… and you can’t separate it out,” she said. “I’m speechless to be honest… it does make me quite angry.”

Read more from Sky News:
Family hail inquest into death of boy sent home from A&E
Fourteen injured after kids’ rollercoaster ‘derails’

A Home Office spokesperson told Sky News it is “working tirelessly to tackle the scourges of violence against women and girls and child sexual abuse”.

“These issues are complex and run deep within the fabric of society,” they added.

“The government wholly recognises that they overlap. But it also recognises that concerted action is needed to tackle child sexual abuse which is why we have set out a range of actions… and why we are launching a national inquiry into grooming gangs.”

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King to warn that sacrifices of VJ Day veterans should ‘never be forgotten’

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King to warn that sacrifices of VJ Day veterans should 'never be forgotten'

The King will issue a warning that the sacrifices of the VJ Day veterans should “never be forgotten” as they “gave us more than freedom; they left us the example of how it can and must be protected”.

In an audio message, due to be released on Friday morning to mark 80 years since the end of the Second World War in the Far East, King Charles will describe how the heroic actions of those sent to fight there and the brutal treatment of civilians “reminds us that war’s true cost extends beyond battlefields, touching every aspect of life”.

In what could be interpreted as him alluding to current world events and conflicts, he will emphasise the importance of international collaboration, saying that victory in 1945 demonstrated that “in times of war and in times of peace, the greatest weapons of all are not the arms you bear but the arms you link”.

Pic: PA
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Pic: PA

The six-minute audio message to the Nation, Realms and Commonwealth to mark VJ Day, echoes the audio broadcast made by his grandfather, King George VI, which the King will reference.

He recorded it in the Morning Room at Clarence House earlier this month.

Victory over Japan (VJ Day) was declared on 15 August 1945, following Imperial Japan’s surrender to Allied Forces.

With Victory in Europe (VE Day) declared in May 1945, some have felt that historically VJ Day has been overlooked, undervaluing the sacrifices of those who continued to fight on for another three months.

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In his message, the King will say that the service and sacrifice of those who fought and died in the Pacific and Far East “shall never be forgotten”.

He will also refer to the experience endured by prisoners of war and to the innocent civilians of occupied lands in the region.

Read more:
UK veteran, 100, recalls witnessing Japan’s Second World War surrender

Survivors’ relatives pledge to make Nagasaki last ever atomic bomb site
My grandmother survived world’s deadliest air raid

King Charles and Queen Camilla will also publicly mark the anniversary by attending a national service of remembrance at the National Memorial Arboretum in Staffordshire.

The service, run in partnership with the Royal British Legion, will be attended by Burma Star recipients, a veteran of the British Indian Army and those involved in the Battles of Kohima and Imphal.

Prisoners of war held across the region and veterans stationed in the UK or Commonwealth countries who contributed to the war effort will also attend. A two-minute national silence will be held at midday.

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British veteran, 100, recalls witnessing Japan’s Second World War surrender on USS Missouri

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British veteran, 100, recalls witnessing Japan's Second World War surrender on USS Missouri

A British veteran has spoken about how he witnessed Japan’s wartime surrender up close as a 20-year-old sailor.

Reg Draper was off Japan’s coast on the HMS Duke of York when the captain announced the war was ending.

Recalling that moment – 80 years ago today – he said cheers went up from the battleship’s crew.

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Why is it important to mark VJ Day?

Mr Draper saw the Japanese sign the agreement on USS Missouri when he went on board to help his friend, who was the ship’s photographer.

“All the ships mustered in Tokyo Bay with the USS Missouri, which was the American ship, and it was on the Missouri where they signed the peace treaty,” the 100-year-old recalled.

“Then we all came back down to Australia and we went and celebrated – we went down to Tasmania and everybody had four days leave in Hobart.

“Everybody wanted to take us to their home and there were a couple of dances in the dance hall.”

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Mr Draper still has a photo showing the peace deal being signed. Pic: Royal British Legion/PA
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Mr Draper still has a photo showing the peace deal being signed. Pic: Royal British Legion/PA

Mr Draper got a letter recognising his presence at the surrender. Pic: Royal British Legion/PA
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Mr Draper got a letter recognising his presence at the surrender. Pic: Royal British Legion/PA

Mr Draper, who grew up in Leeds, was a stores assistant on the Duke of York after volunteering on his 18th birthday.

His duties included rationing out the rum so all the sailors could get their 11am hit. He said senior crew got theirs neat while everyone else had theirs watered down.

He also recalled being clattered by Prince Philip after the Queen’s future husband, who was on a destroyer escorting his ship, came aboard.

A view looking out over the HMS Duke of York. Pic: AP
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A view looking out over the HMS Duke of York. Pic: AP

Mr Draper met Prince Philip again in the 70s - but the hockey wasn't mentioned. Pic: Royal British Legion/PA
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Mr Draper met Prince Philip again in the 70s – but the hockey wasn’t mentioned. Pic: Royal British Legion/PA

“We used to have deck hockey on the quarter deck and it was murder playing deck hockey,” said Mr Draper.

“He [Philip] knocked me over once and then the next time he came round he hit me, there’s still a mark there, he gave me a clout with his hockey stick.

“He came to see me just to see how I was. They just put a stitch in and it was alright.”

The pair met again in 1972 when Mr Draper was training sea cadets for the Duke of Edinburgh awards.

He said Philip noticed his medals and recalled escorting the ship – but didn’t mention the hockey game.

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Hiroshima survivor describes moment of blast

Mr Draper’s time on the Duke of York included Arctic convoys to deliver supplies to Russia and sailing to Sydney, Australia, in 1945 before joining the East Indies Fleet.

“We started going up to the islands, kicking the Japanese out of the islands as we went,” he recalled.

Japan surrendered after the US dropped two nuclear bombs on Hiroshima and Nagasaki, on 6 and 9 August.

Read more:
Hiroshima survivor has stark warning for us all
My grandmother survived world’s deadliest air raid

Mr Draper now lives in Elton in Cheshire. Pic: PA
Image:
Mr Draper now lives in Elton in Cheshire. Pic: PA

Mr Draper turned 21 on the trip back to Europe and said 2,000 people were on board as they had picked up prisoners of war.

He went on to become an insurance salesman and said he’s planning to watch today’s 80th anniversary commemorations from his home in Elton, Cheshire.

The King released an audio message in which he said the sacrifices of VJ Day veterans should “never be forgotten”.

He described how the heroic actions of those sent to fight in the Far East, as well as the brutal treatment of civilians, “reminds us that war’s true cost extends beyond battlefields, touching every aspect of life”.

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