Woman has combined pig kidney transplant and heart pump implant in world first

Published

4 weeks ago

April 25, 2024

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A US woman has become the first person in the world to undergo a pig kidney transplant and also have a mechanical heart pump surgically implanted.

Lisa Pisano’s combination of heart and kidney failure had left her too ill to qualify for a traditional transplant.

The 54-year-old, from New Jersey, became the first woman and only the second patient ever to receive a genetically-modified pig kidney when she “took a chance”.

In a world first, Ms Pisano allowed doctors at NYU Langone Transplant Institute in New York to implant a mechanical pump to keep her heart beating and then a few days later to transplant a pig kidney.

She said: “I was at the end of my rope. I just took a chance.

“And you know, worst case scenario, if it didn’t work for me, it might have worked for someone else and it could have helped the next person.”

Her husband Todd said: “With this surgery I get to see my wife smile again.”

Last month, it was revealed a 62-year-old man became the first person to be transplanted with a pig kidney.

Other transplant experts are said to be closely watching the progress of Ms Pisano, who doctors said was recovering well.

Dr Robert Montgomery, director of NYU Langone Transplant Institute, recalled there were cheers in the operating room as the organ immediately started making urine.

Speaking about the early results of the surgery, he added: “It’s been transformative.”

But Dr Nader Moazami, the NYU cardiac surgeon who implanted the heart pump, warned “we’re not off the hook yet”.

The two surgeries took place within eight days and needed emergency permission from US health agency, the Food And Drug Administration.

More than 100,000 people are on the transplant waiting list in the US – most need a kidney, but thousands die waiting.

Raising hopes of filling the shortage of donated organs, several biotech companies are genetically modifying pigs so their organs are more human-like and less likely to be destroyed by people’s immune system.

Ms Pisano’s case is the latest in a string of attempts to make animal-to-human transplantation a reality.

US

Ticketmaster owner Live Nation facing monopoly lawsuit – after criticism from Taylor Swift

Published

3 hours ago

May 23, 2024

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Ticketmaster owner Live Nation facing monopoly lawsuit - after criticism from Taylor Swift

The US Justice Department (DOJ) is suing Live Nation, arguing the big concert promoter and its subsidiary, Ticketmaster, have been “monopolising” the live events industry.

The antitrust lawsuit was launched on Thursday by the DOJ, 30 US states, and the District of Columbia, with US Attorney General Merrick Garland saying: “It is time to break up Live Nation.”

The entertainment company merged with Ticketmaster back in 2010. Through Ticketmaster, Live Nation now controls roughly 80% or more of big venues’ primary ticketing for concerts, the suit says.

A Live Nation spokesperson said the company would defend itself “against these baseless allegations” and said the DOJ would lose in court because the case “ignores the basic economics of live entertainment”.

Ticketmaster, which overwhelmingly dominates the ticketing industry, has for years left fans and artists frustrated by hidden fees, rising costs, and limited ticket availability due to presales.

Its dominance in the industry came under scrutiny by US politicians in 2022, when Ticketmaster was forced to cancel its general sale of tickets to Taylor Swift’s much-anticipated Eras tour due to “extraordinarily high demands”.

At the time, the superstar criticised Ticketmaster on social media, saying it was “excruciating for me to just watch mistakes happen with no recourse” after Swift’s fans reported long wait times and site outages during the presales.

The star said 2.4 million fans had been able to purchase tickets, which was “truly amazing… but it really p***** me off that a lot of them feel like they went through several bear attacks to get them”.

Thursday’s legal action underscores the aggressive approach President Joe Biden’s antitrust enforcers have adopted as they seek to create more competition in a wide range of industries, from “big tech”, to healthcare, and groceries.

In March, the Justice Department filed a lawsuit against Apple alleging that the tech giant has monopoly power in the smartphone market.

“Live Nation relies on unlawful, anticompetitive conduct to exercise its monopolistic control over the live events industry
in the United States at the cost of fans, artists, smaller promoters, and venue operators,” Mr Garland said.

He added that, as a result, fans pay more in fees, artists have fewer opportunities to perform, and smaller promoters get squeezed out.

The lawsuit says Live Nation directly manages more than 400 musical artists and controls around 60% of concert promotions at major venues.

It also owns or controls more than 265 concert venues in North America.

In 2010, the Justice Department approved Ticketmaster’s controversial merger with Live Nation, with conditions intended
to stop the combined company from harming competition.

In 2020, a court extended most of the DOJ’s oversight of the merger to 2025 because, the department said, Ticketmaster
retaliated against stadiums and arenas that opted to use other ticketing companies.

Live Nation has said in the past that it was confident its business practices were legal, and that the probe had been prompted by complaints from rivals, including re-sellers.

A spokesperson for the company said on Thursday that the lawsuit “won’t solve the issues fans care about relating to ticket prices, service fees, and access to in-demand shows”.

Live Nation added that “calling Ticketmaster a monopoly may be a PR win for the DOJ in the short term, but it will lose in court because it ignores the basic economics of live entertainment” – stating that most service fees go to venues.

US

Judge blocks foreclosure auction of Elvis Presley’s Graceland

Published

12 hours ago

May 23, 2024

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Judge blocks foreclosure auction of Elvis Presley's Graceland

A judge has blocked the auction of Elvis Presley’s former home, by a company that claimed his estate failed to repay a loan which used the property as collateral.

Shelby County Chancellor JoeDae Jenkins issued a temporary injunction against the proposed auction of Graceland that had been scheduled for Thursday.

Mr Jenkins’ injunction essentially keeps in place a previous restraining order he had issued after the singer’s granddaughter Riley Keough filed a lawsuit to fight what she claimed was a fraudulent scheme.

A public notice for a foreclosure sale of the 13-acre estate in Memphis, Tennessee, posted earlier in May said Promenade Trust, which controls the Graceland museum, owes $3.8m (£3m) after failing to repay a loan taken out in 2018.

Keough, an actor, inherited the trust and ownership of the home following the death of her mother, Lisa Marie Presley, last year.

Naussany Investments and Private Lending said Lisa Marie Presley had used Graceland as collateral for the loan, according to the foreclosure sale notice.

Keough alleged that Naussany presented fraudulent documents regarding the loan in September 2023.

Neither Keough nor lawyers for Nassauny Investments were in court.

“Lisa Maria Presley never borrowed money from Naussany Investments and never gave a deed of trust to Naussany Investments,” Keough’s lawyer submitted in the lawsuit.

Kimberly Philbrick, the notary is listed on Nassauny’s documents, indicated that she never met Lisa Marie Presley nor notarised any documents for her, the court filing said.

Graceland opened as a museum and tourist attraction in 1982 as a tribute to Elvis, five years after the King of Rock n Roll died in aged 42 in 1977.

He purchased Graceland Mansion in 1957 and lived there until his death.

It now draws hundreds of thousands of visitors each year, and a large Elvis-themed entertainment complex across the road from the museum is owned by Elvis Presley Enterprises.

US

Oregon: Woman crushed by grand piano shows ‘amazing spirit’ after being told she will never walk again

Published

1 day ago

May 22, 2024

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Oregon: Woman crushed by grand piano shows 'amazing spirit' after being told she will never walk again

A woman has been left unable to walk after a piano slipped and dropped on her while she was helping a friend move the instrument.

Danielle Drummond, 28, who had recently relocated from Cleveland, Ohio, to Oregon for a fresh start, is now hoping for a scientific breakthrough after the ordeal left her needing both a wheelchair and a carer.

She told Cleveland-based broadcaster 19 News she had tried to stabilise the piano when offering to help last month, but her friend lost her grip.

“She dropped like a whole upright grand piano on me, and it severed my spinal cord,” Ms Drummond said.

“Now, I’m paralysed from the waist down.”

Ms Drummond has no family in Eugene, the city in Oregon where she lives, and also needs to find a permanent home, having been living in a van with her dog, Lotus.

Compounding her problems, she does not know how she would begin to move back to her family in Cleveland and transfer all her belongings and medical equipment.

Her sister has set up a fundraising page to “support future medical needs”, with the aim of raising $10,000 (£7,850).

“Our family thanks you for all your support, consideration, thoughts, love and prayers,” her sister Rosie Hayne wrote, describing Ms Drummond as “strong”, “wise”, and “down to earth”.

In an update on the GoFundMe page, Ms Hayne added: “She wants to make it clear that she is not expecting to ever walk again.

“She has accepted the reality of her situation. But she has an amazing spirit and an overall positive outlook, focusing on what she can do.”

Ms Drummond told 19 News she hopes people going through similar circumstances “don’t give up”.