A 91-year-old man has become the first person in England to be fitted with a ground-breaking artificial cornea.
Cecil ‘John’ Farley, 91, said his sight was now improving thanks to the procedure, which he underwent after 15 years of suffering from problems with his eyes.
The cornea is the clear outer layer at the front of the eyeball – and is described by the NHS as the “window to the eye”.
A person can suffer from vision problems and pain if the thin transparent covering is damaged by disease or injury – with those affected often left facing a long wait for a human transplant.
However, it is hoped that the artificial device, called EndoArt, will slash waiting times, ease pressure on the NHS and eliminate the risk of the human body rejecting corneas received from an organ donor.
Mr Farley, from Chobham in Surrey, said he was overjoyed by the transplant – in his right eye – because it meant he could continue to see his 83-year-old wife Elizabeth.
He said: “I can still see my wife after 63 years of marriage, we can just carry on as normal and live life as fully as we can.
“It makes your life fuller when your eyes work properly – you don’t realise how debilitating it is until it happens to you.”
Before the surgery, Mr Farley had no vision in his right eye – but his sight has slowly been improving ever since the procedure in February.
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He said: “It has made a great difference to my sight. It was very blurred and I couldn’t distinguish a face.
“Now I can see better with it, the brighter the light the better. It’s coming along slowly – they said it could take up to a year.”
The artificial cornea has been compared to a contact lens. The device, which replaces the inner part of the cornea, is surgically attached to the eye by a single stitch and is put in place with a gas bubble.
Patients could see major impact
One of the biggest advantages of using artificial corneas is the huge reduction in waiting time for the procedure. It means patients on the elective backlog who risk further deterioration in their vision can be seen months earlier than they would waiting for a cornea transplant from an organ donor.
But at the moment the artificial cornea operation can only be carried out on patients who meet the “complex eye” criteria. These include patients whose previous human cornea transplant has failed.
Consultant ophthalmologist Tom Poole, who carried out the procedure, is confident the surgery can be rolled out to “virgin eye” patients in the future. These are patients with no previous history of eye surgery.
Mr Poole told me the international ophthalmology community was growing increasingly confident with artificial corneas which are relatively easy to make and their production could be scaled up quite easily.
He and his colleague Hanbin Lee at Frimley Health NHS Foundation Trust have already carried out three more operations since February.
The latest tests on Mr Farley suggest the procedure has been a success. Three more patients have been identified and are listed for surgery.
Only 200 people worldwide, including Mr Farley, have been fitted with an EndoArt so far, but there are hopes it can be more widely rolled out.
Organic cornea transplants usually come from deceased donors. A total of 4,719 were donated to the NHSin 2022/23, according to the latest available figures.
Consultant ophthalmologist Thomas Poole, from Frimley Health NHS Foundation Trust in Surrey, which carried out the procedure, described the artificial cornea as a “great advancement”.
He said there had been fears that Mr Farley was “kind of getting to [his] last hope” after a previous human transplant failed.
Mr Poole said: “I had a very frank discussion with him before and I said: ‘Look, your graft has failed, you’re back on the waiting list. Because your other eye sees quite well, you’re not a high priority on the waiting list and you could be waiting for another year’.
“He’s in his 90s now and said ‘I just can’t wait that long. Is there anything else?’ And so this sprung to mind.
“I had just read a publication on very good reports from this artificial graft and it was that that made me think actually, maybe we could use this for John.”
Mr Poole and his colleague Hanbin Lee have now successfully given four patients artificial corneas in the last two months and the initial results have shown an improvement in vision.
He added: “Looking forward to the future, I think this may end up replacing human corneas for certain types of corneal graft patients.
“In maybe 10 or 20 years’ time – this may become the norm where we don’t need a human cornea, and we can just take one out of the box.”
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Conservative Party leader Kemi Badenoch has called on Sir Keir Starmer to sack Treasury minister Tulip Siddiq over allegations she lived in properties linked to allies of her aunt, Sheikh Hasina, the deposed prime minister of Bangladesh.
It comes after the current Bangladeshi leader, Muhammad Yunus, said London properties used by Ms Siddiq should be investigated.
He told the Sunday Timesthe properties should be handed back to his government if they were acquired through “plain robbery”.
Tory leader Ms Badenoch said: “It’s time for Keir Starmer to sack Tulip Siddiq.
“He appointed his personal friend as anti-corruption minister and she is accused herself of corruption.
“Now the government of Bangladesh is raising serious concerns about her links to the regime of Sheikh Hasina.”
Ms Siddiq insists she has “done nothing wrong”.
Her aunt was ousted from office in August following an uprising against her 20-year leadership and fled to India.
On the same day, the prime minister said: “Tulip Siddiq has acted entirely properly by referring herself to the independent adviser, as she’s now done, and that’s why we brought into being the new code.
“It’s to allow ministers to ask the adviser to establish the facts, and yes, I’ve got confidence in her, and that’s the process that will now be happening.”
Police in Aberdeen have widened the search area for two sisters who disappeared four days ago in the city.
Eliza and Henrietta Huszti, both 32, were last seen on CCTV on Market Street after leaving their home on Tuesday at around 2.12am.
The sisters – who are part of a set of triplets and originally from Hungary – crossed the Victoria Bridge to the Torry area and turned right on to a footpath next to the River Dee.
They headed in the direction of Aberdeen Boat Club but officers said there is no evidence to suggest the missing women left the immediate area.
Specialist search teams, police dogs and a marine unit have been trying to trace the pair.
Further searches are being carried out towards the Port of Aberdeen’s South Harbour and Duthie Park.
Police Scotland said it is liaising with authorities in Hungary to support the relatives of the two sisters.
Chief Inspector Darren Bruce said: “Eliza and Henrietta’s family are understandably extremely worried about them and we are working tirelessly to find them.
“We are seriously concerned about them and have significant resources dedicated to the inquiry.”
The sisters, from Aberdeen city centre, are described as slim with long brown hair.
Officers have requested businesses in and around the South Esplanade and Menzies Road area to review their CCTV footage for the early morning of Tuesday 7 January.
Police added they are keen to hear from anyone with dashcam footage from that time.
TV presenter Katie Piper has revealed her decision to get an artificial eye, 16 years after an acid attack that left her with life-changing injuries and partial blindness.
The Loose Women panellist, 41, is an advocate for those with burns and disfigurement injuries.
She shared a video of her being fitted with the prosthetic on Instagram.
Piper said: “After many years battling with my eye health, I’ve reached the end of the road somewhat, and the decision has been made to try a prosthetic eye shell.
“This marks the start of a journey to have an artificial eye, with an incredible medical team behind me.
“As always I’m incredibly grateful to all those in the NHS and private health care system for their talent and kindness.
“I will share my journey, I’m hopeful and nervous about being able to tolerate it and would love to hear from any of you in the comments if you’ve been on this journey or have any advice.”
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Commenting on the post, presenter Lisa Snowdon said Piper was a “warrior” and a “true inspiration”.
Piper has undergone hundreds of operations after suffering an acid attack arranged by her ex-boyfriend in March 2008.
She gave up her right to anonymity and made a documentary in 2009 called Katie: My Beautiful Face.
Piper also founded the Katie Piper Foundation which supports survivors of life-changing burns and scars, and has received an honorary doctorate from the Royal College of Surgeons to mark her ground-breaking work.
She was made an OBE in 2021 for her services to charity and burn victims.