A “game-changer” pill is to be offered to tens of thousands of smokers in England who are trying to quit.
Varenicline can be more effective than nicotine-replacement gum or patches, and as effective as vapes, in helping people to stop smoking, according to NHS England.
The daily pill is said to reduce cravings and the pleasurable effects of nicotine that keep people addicted.
It also helps with withdrawal symptoms such as irritability or sleeping problems and patients usually take a 12-week course.
It’s estimated it could help more than 85,000 people per year and prevent up to 9,500 smoking-related deaths over the next five years, according to University College London (UCL).
Varenicline will become another option for people using NHS stop smoking services in England.
A branded version of the smoking cessation pill – known as Champix – was previously prescribed, but then withdrawn by Pfizer in 2021 as a precaution after an impurity was discovered.
However, the NHS said a generic version of the drug, from pharmaceutical firm Teva UK, has now been approved as safe by the Medicines Health and Regulatory Authority (MHRA).
It said another pill that works in a similar way, cytisine, is also being reviewed by the National Institute for Health and Care Excellence (NICE) and could be made available in the future.
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Supplying varenicline is part of an effort to make more effective treatments available while saving more than £500m for the taxpayer, said NHS England chief executive Amanda Pritchard.
In a speech later, she will say the pill could be “a game-changer” for smokers. Meanwhile, Health Secretary Wes Streeting said it would save lives and millions of pounds for the NHS.
“Taken alongside our tobacco and vapes bill, the government and NHS are building a healthy society to help power a healthy economy,” said Mr Streeting.
Around six million people – one in eight UK adults – are smokers and there were more than 400,000 hospital admissions in England attributed to smoking in 2022-23, according to the NHS.
Around one in six (16%) of all admissions for respiratory diseases were estimated to be smoking-related, while it also caused 8% of admissions for cancers and 7% for cardiovascular disease.
Each year, the NHS spends around £2.5bn on treating health issues caused by smoking – the leading cause of preventable illness and deaths.
The pair have each been charged with murder and attempting to defeat the ends of justice.
The suspects, both of Greenock, made no plea to the two separate charges last week and were remanded in custody ahead of their next court appearance.
A 45-year-old man previously arrested in connection with assault and a 41-year-old man arrested at the same time as the two women have both been released pending further enquiries.
Police Scotland previously said officers investigating Mr Best’s death were carrying out enquiries into a report of a disturbance in Lansbury Street, Greenock, which took place between 11pm on 10 November and 3am on 11 November.
A force spokesperson said: “Enquiries are ongoing.”
Sir Keir Starmer has called the pile of fly-tipped illegal waste next to a river in Oxfordshire “utterly appalling” and said “all available powers” will be used to make those responsible cover the cost of the clean-up.
Liberal Democrat leader Sir Ed Davey said the pile of rubbish in a field beside the River Cherwell in Kidlington is now 150m long and up to 12m high, adding that water is “now lapping against the waste and carrying it into the river”.
Speaking at PMQs, Sir Ed said it is just one of many sites where organised criminal gangs are “illegally dumping their waste onto our countryside and getting away with it”.
“This is a shocking environmental emergency. So will he instruct the Environment Agency to clean it up now?” Sir Ed added.
Sir Keir responded in the House of Commons on Wednesday, calling the scenes “utterly appalling”.
The prime minister said: “A criminal investigation, as he knows, is under way. Specialist officers are tracking down those responsible.
“The Environmental Agency, in answer to this question, will use all available powers to make sure that the perpetrators cover the cost of the clean-up, which must now follow.”
Image: Pic: Sky News
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UK’s ‘biggest ecological disaster’
Sir Keir added: “We have boosted the Environment Agency’s budget for tackling waste crime by 50%, giving councils new powers to seize and crush fly-tippers, vehicles and lawbreakers can now face up to five years in jail.”
Earlier this week, Calum Miller, Liberal Democrat MP for Bicester and Woodstock, said recent heavy rainfall brought by Storm Claudia at the weekend had made the situation more urgent, and meant the rubbish was slowly floating towards the river, which eventually flows through Oxford and feeds the Thames.
Image: Calum Miller, Liberal Democrat MP for Bicester and Woodstock
Image: Pic: Sky News
Mr Miller also told Sky News on Sunday it was the first time he had seen anything on this scale, questioning whether the Environmental Agency had the resources to deal with it.
The cost of removing the waste is estimated to be more than the entire annual budget of the local council, which is about £25m.
With the site on a floodplain, Mr Miller listed what he saw as the three major environmental risks – waste being washed into the waterways, rain seeping through the waste and carrying toxins into the water and the danger of decomposing chemicals presenting a fire risk.
The site is adjacent to the A34, a busy road running through cities including Oxford and Birmingham.
He said the police had used a helicopter with a heat-seeking camera, and could see that some of the waste was beginning to decompose.
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‘Mountain’ of waste dumped
Mr Miller said he believed the Environment Agency was first made aware of the issue back in July.
He said he believed it was the work of “organised criminal gangs” and raised a “bigger systemic problem around the country”, with “dumps are cropping up in more and more places”.
He added: “My concern is the Environmental Agency lacks the resources to deal with criminal activity on this scale. I’m calling on the government to take action and ensure those who are dealing with such incidents have the powers they need to tackle it at source.”
Anna Burns, the Environment Agency’s director for the Thames area, said on Wednesday: “Most of the tipping happened before we were aware of it. As soon as we were aware, we acted quickly and decisively.”
Ms Burns said: “We are pursuing this as a criminal investigation and currently following a number of leads, and we are laser focused on pursing that investigation.
“And we are working with partners to understand the risks associated with the site.”
She said the agency will pursue the perpetrators to make them pay for the “blight on the landscape” they had caused.
An Oasis fan who fell to his death at Wembley Stadium was the victim of a “tragic accident”, a pre-inquest review has heard.
Bournemouth man Lee Claydon, 45, died following the incident at the London venueon 2 August.
Detective Sergeant James Raffin, from the Met Police, said there were “no concerns” from Mr Claydon’s toxicology report.
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Liam and Noel Gallagher performed on the same stage together for the first time in 16 years.
He also said that while Mr Claydon had drunk alcohol, this was “expected” and “normal for any of the people attending” the Oasis gig.
The force had also ruled out the possibility of suicide, he said.
He told Barnet Coroner’s Court the police had now completed their investigation into his death
He said: “From a police point of view, this is no longer a criminal prosecution.
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“We do not suspect any third party involvement.
“This, from everything we have seen, was a tragic accident.
“From a police point of view, I would say our investigation is complete.”
Image: Liam Gallagher and Noel Gallagher during the Oasis tour this year. Pic: Reuters
DS Raffin said he was aware the family had concerns over the “circumstances on the night”, and said he would pass these on to officials at Brent Council.
“All I know is there was beer everywhere, it’s slippery, he slipped apparently, we do not know the rest of it, there’s questions about the barriers.”
Brent Council will now review the police report.
Image: Oasis fans on Wembley Way, ahead of the first night of the Oasis Live ’25 tour opening at Wembley Stadium in London. Pic: PA
Mr Claydon, a landscape gardener, fell during a gig that formed part of Oasis’ sell-out Live ’25 reunion tour – their first since splitting in 2009.
The inquest opening, which took place in September, heard that the father-of-three was taken to a medical centre in Wembley after the fall, where he was pronounced dead at 10.38pm.
A post-mortem examination on 6 August gave his preliminary medical cause of death as “multiple bodily injuries”.
Senior Coroner Andrew Walker told the review hearing the full inquest will take place on 26 February next year.
He said: “It looks like we are going to be in a position next February to have reports from the London Borough of Brent over the circumstances and also we will have by then the police investigation report.”
Oasis previously said in a statement: “We are shocked and saddened to hear of the tragic death of a fan at the show.
“Oasis would like to extend our sincere condolences to the family and friends of the person involved.”
In a statement at the time of the fall, a Wembley spokesperson said: “The stadium operates to a very high health and safety standard, fully meeting legal requirements for the safety of spectators and staff, and is certified to and compliant with the ISO 45001 standard.
“We work very closely and collaboratively with all relevant event delivery stakeholders – including event owners, local authorities, the Sports Grounds Safety Authority and the police – to deliver events to high standards of safety, security and service for everyone attending or working in the venue.”