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Sponsored Content by MGI Reviewed by Olivia Frost Dec 6 2024 Thought Leaders Wirulda Pootakham Director Thailand's National Omic Centre

Thailand's coastal ecosystems, particularly its mangroves, are rich in biodiversity and play critical roles in coastal protection, carbon storage, and marine productivity. However, these ecosystems face severe threats from climate change, pollution, and habitat degradation. Genomic conservation in Thailand seeks to protect the genetic diversity of mangroves by using modern techniques such as DNA sequencing and genetic monitoring.

In this interview, Wirulda Pootakham, the Director of Thailand's National Omic Centre, talks to NewsMedical about genomic conservation in Thailand's mangroves. Could you tell us about your job at the National Omic Centers and how you came to specialize in ecosystems like mangroves?

My name is Wirulda Pootakham. I am the Head of the Genomic Research Lab at Thailand’s National Omic Centre. My colleagues and I conduct genomic research, focusing on genetic diversity in crucial ecosystems such as mangrove forests.

These ecosystems are important for Thailand’s biodiversity and are sensitive to natural and human-induced stressors. Understanding their genetic makeup might help ensure their persistence despite considerable threats from climate change and habitat destruction.

Image Credit: AofLine/Shutterstock.com Could you elaborate on the key species found in Thailand, the risks they face, and why genetic diversity is so important to their resilience?

Thailand’s mangroves are home to approximately 81 species, with 34 designated “true” mangroves. The principal species are Sonnertia, Rhizophora, Ceriops, and Bruguiera.

Most of these species grow in southern Thailand, particularly along the shore and intertidal zones. Unfortunately, over the last five decades, almost 60 % of our mangrove forests have been devastated due to deforestation, aquaculture expansion, and urbanization.

Genetic variety is critical for mangroves because it allows plants to adapt to environmental stressors, including rising temperatures, salinity fluctuations, and disease. Previous restoration projects did not focus on genetic diversity, reducing resilience. Our research seeks to solve this by supporting genetically varied populations in restoration efforts, making them more resistant to attacks. Tackling Ecosystem Challenge with MGI Sequencing Technology in Thailand Play How can sequencing technologies contribute to mangrove ecosystem studies?

Sequencing technologies provide detailed genomic information that helps researchers understand the adaptations of mangroves to their challenging intertidal environments.

These technologies enable the assembly of high-quality reference genomes, which are essential for studying genetic traits linked to stress tolerance, reproduction, and survival in saline and hypoxic conditions.

This genetic insight supports conservation efforts by identifying traits critical for resilience and restoration, enabling more informed management of mangrove ecosystems.

Image Credit: fokke baarssen/Shutterstock.com Could you explain how MGI’s technology has helped you enhance your research on mangroves?

MGI has been a key collaborator in supplying us with high-quality sequencing technology. We have employed MGI-seq for whole-genome sequencing and other applications, such as RAD-seq, to quantify genetic diversity accurately. Related StoriesMGI Tech unveils new european headquarters in Berlin, GermanyMGI Techs DNBSEQ-E25 and G99 platforms set record for sequencing applications at high altitude?MGI Tech shares new data on core DNEBSEQ technology and showcases latest sequencing innovations at ESHG 2024

So far, we have sequenced around 15 of Thailand’s 80 mangrove species. This method has also enabled us to find SNP markers, which are crucial for assessing genetic diversity within and between animal populations. 

These findings are critical with rising ocean temperatures triggering bleaching events, as we experienced this year. Our work with MGI also includes essential agricultural crops like rice, sugarcane, and corn, where genetic insights might improve resilience to environmental changes.

Image Credit: Zhukova Valentyna/Shutterstock.com How can technologies like RAD-seq help address the challenges associated with studying mangroves?

Studying mangroves presents several challenges, including understanding their genetic diversity, biodiversity, and evolutionary adaptations. Restriction Site-Associated DNA Sequencing (RAD-seq) technology is very valuable in addressing these challenges.

It provides sufficient Single Nucleotide Polymorphism (SNP) data to comprehensively analyze the genetic variation of mangrove populations. This allows researchers to study biodiversity, genetic structure, and evolutionary history more effectively.

By identifying key genetic markers, RAD-seq enables us to understand how mangroves have evolved and adapted, which is essential for their conservation and restoration efforts. Moreover, this technique can help identify endangered or vulnerable species within mangrove ecosystems, further supporting their protection About Wirulda Pootakham

Wirulda Pootakham earned her Bachelor’s degree in Plant Molecular Biology from Cornell University in 2002, graduating summa cum laude. She completed her PhD in Cell and Molecular Biology at Stanford University in 2010 and joined the Genomic Research Lab at the National Center for Genetic Engineering and Biotechnology (BIOTEC) in Thailand.

Her research focuses on using genomic technologies to develop elite varieties of economically important plants like oil palm, rubber tree, cassava, and sugarcane. She has received several awards, including the Young Technologist Award from the Foundation for the Promotion of Science and Technology under the Patronage of His Majesty the King in 2017 and the Taguchi Prize for Outstanding Research Achievement in Biotechnology from the Thai Society for Biotechnology in 2022.

Pootakham has been involved in projects addressing environmental issues of coral bleaching in the Gulf of Thailand and Andaman Sea. In recognition of her pioneering work in assessing coral genetic diversity in Thai waters, she was honored with the UNESCO-L’Oréal For Women in Science Fellowship in 2018. Her recent projects include assessing genetic diversity in mangrove populations to support conservation efforts along Thailand's coasts. About MGI

 

MGI Tech Co., Ltd. (or its subsidiaries, together referred to as MGI) is committed to building core tools and technologies that drive innovation in life science. Our focus lies in research & development, manufacturing, and sales of instruments, reagents, and related products in the field of life science and biotechnology. We provide real-time, multi-omics, and a full spectrum of digital equipment and systems for precision medicine, agriculture, healthcare, and various other industries.

Founded in 2016, MGI has grown into a leader in life science, serving customers across six continents and establishing research, manufacturing, training, and after-sales service facilities globally. MGI stands out as one of the few companies capable of independently developing and mass-producing clinical-grade gene sequencers with varying throughput capacities, ranging from Gb to Tb levels. With unparalleled expertise, cutting-edge products, and a commitment to global impact, MGI continues to shape the trajectory of life sciences into the future.

As of June 30, 2024, MGI has a team over 2,670 employees, with research and development personnel accounting for approximately 32.16%. Our business spans over 100 countries and regions worldwide, serving more than 3,000 users.

Sponsored Content Policy: News-Medical.net publishes articles and related content that may be derived from sources where we have existing commercial relationships, provided such content adds value to the core editorial ethos of News-Medical.Net which is to ducate and inform site visitors interested in medical research, science, medical devices and treatments.

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Environment

Huawei Maextro set to challenge Maybach, Rolls-Royce in China with 852 hp

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Huawei Maextro set to challenge Maybach, Rolls-Royce in China with 852 hp

Packing up to 852 hp and a cutting-edge technology stack developed by Huawei, Chinese luxury brand Maextro just revealed its latest entry into the Mercedes-Maybach EQS and Rolls-Royce Spectre segment of ultra-luxe EVs. Meet the all-new Maextro S800.

Despite a somewhat steady stream of new Chinese EVs that defy expectations and threaten to re-set the global order of performance cars, semi trucks, and just about everything in between, brands like Maybach, Rolls-Royce, and even Bentley have seemed relatively “safe,” in the sense that their value is based on something a bit less objective than lap times or kW/mile.

The new Huawei Maextro S800, first shown as a series of renderings late last year, seems to have found some of Henry Rolls’ secret sauce – and they’ve sprinkled it liberally all over the S800.

Huawei sparkles – literally

The shimmering, sparkly, fiber-optic headliner was pioneered by Rolls-Royce over a decade ago, pushing back against the more open and accessible glass-roofs that were becoming popular in the higher end market. Huawei goes a step further, adding similar, Swarovski-like shimmer to not just the headliner – but the door handles, the headlights, projections dancing around the car as you approach it in the street.

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It looks and feels special, in other words. And these cars are all about making their owners feel special. Different.

When Henry Rolls began work on his first US factory in Springfield, Massachusetts way back in 1919, there was supposedly a mantra that management repeated to the workers. It went, “every time you touch the car, you add cost. Make sure you add value.”

I’m not here to argue that Huawei is living up to the same maxim with the Maextro, but I am here to argue that this car’s bespoke, purpose-built platform doesn’t share any parts with a lesser offering from the Mercedes or BMW or Volkswagen lineup in the way that a Maybach, Rolls-Royce, or Bentley does. That may not mean much to you and me, but the people shopping six- and seven-figure cars, it might.

Those well-heeled buyers will get a choice of EREV or “pure” battery electric powertrains good for between 480 and 852 all-electric horsepower. 32 ADAS sensors including both radar and lidar compliment a suite of cameras analyze the road ahead and feed data to Huawei’s ADS road perception system, which is constantly adjusting torque distribution, suspension compression and rebound, and front and rear steering to deliver a tech-driven chauffeur experience that Huawei insists is second to none.

That digital chauffeur is also pretty handy when the weather goes sideways, too. Huawei says the Maextro’s sensor array can help it to increase the detection distance in rain, fog, and dust by 60% compared to the benchmark, while delay was reduced by 40%.

In the event a collision is unavoidable, the car can adjust its stance, seating position, raise the windows, and unlock the central control lock to enable outside help to open the doors. Following the collision, the Maextro S800 switches the redundant power supply and calls for help, as well.

Finally, reports indicate that the Maextro S800 supports the 800V high-voltage system in some trims, suitable for 6C charging, which means it can be energized with up to 390 kW of charging power, taking just 10.5 minutes to charge the 66 kWh battery in the EREV version (523 hp) from 10% to 80%.

The Maextro S800 will enter the Chinese in May this year with a price range of 1 – 1.5 million yuan (about $135–205,000 US).

SOURCE | IMAGES: Maextro, via CarNewsChina.

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Montana’s Bitcoin reserve bill rejected by House lawmakers

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Montana’s Bitcoin reserve bill rejected by House lawmakers

Montana’s House of Representatives voted 41-59 against a bill that could have seen the US state establish a Bitcoin reserve.

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Pope Francis has ‘initial, mild’ kidney problem and still in critical condition, says Vatican

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Pope Francis has 'initial, mild' kidney problem and still in critical condition, says Vatican

The Pope remains in a critical condition and is now showing an “initial, mild” kidney problem – but is “vigilant” and took part in Mass in hospital with those caring for him.

The Vatican statement said Francis hadn’t had any more “respiratory crises” since Saturday evening.

However, a problem with his kidneys has emerged, with blood tests showing “an initial, mild, renal insufficiency, which is currently under control”, according to the update.

The 88-year-old Pope is still having “high-flow oxygen therapy” into his nose, while his hemoglobin value has increased after being given blood transfusions on Saturday.

The Pope has been at Rome’s Gemelli hospital since 14 February and is being treated for double pneumonia and chronic bronchitis.

Sunday evening’s statement said he was “vigilant and well oriented”, but due to the complexity of his case the prognosis is “reserved”.

“During the morning, in the apartment set up on the 10th floor, he participated in the Holy Mass, together with those who are taking care of him during these days of hospitalization,” the update added.

On Sunday morning, the Vatican said the Pope had a “tranquil” night and confirmed he would not lead prayers for the second week running.

Instead, Francis, who has been Pope since 2013, prepared words to be read on his behalf at the recitation of the Angelus.

‘I ask you to pray for me’

The Pope’s message said: “I am confidently continuing my hospitalisation at the Gemelli Hospital, carrying on with the necessary treatment; and rest is also part of the therapy!

“I sincerely thank the doctors and health workers of this hospital for the attention they are showing me and the dedication with which they carry out their service among the sick.

“In recent days I have received many messages of affection, and I have been particularly struck by the letters and drawings from children.

“Thank you for this closeness, and for the prayers of comfort I have received from all over the world! I entrust you all to the intercession of Mary, and I ask you to pray for me.”

The message is understood to have been written in the last few days.

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‘The Pope is like family to us’

On Saturday night, the Vatican said the Pope was in a critical condition after a “prolonged respiratory crisis” that required a high flow of oxygen.

It said he’d had blood transfusions after tests revealed thrombocytopenia, which is associated with anaemia.

Millions around the world have been concerned about his increasingly frail health – and his condition has given rise to speculation over a possible resignation.

Faith is never lost but it feels optimism is fading

By Lisa Holland, Sky correspondent in Vatican City

It’s hard to imagine a Sunday in the Vatican City without the Pope. Every week – unless he’s travelling – he is a constant, appearing at the same Vatican windows to deliver his message.

Instead, his written words were distributed by Vatican officials. In his message, the Pope thanked his doctors and people around the world for their good wishes.

But it seems the upbeat message was written before the dramatic downturn in the Pope’s health, which has left him in a critical condition. The business and the events of the Church are continuing in his absence.

Faith is never lost but it feels like optimism is fading and we are living through the last days of Pope Francis.

In St Peter’s Square the sun shone – and a gentle light fell on the ancient stone of the basilica.
The beauty and pageantry of columns of deacons and visitors filing in for a special mass as part of the Catholic Church’s jubilee year sat awkwardly with the prognosis of the Pope’s ailing health.

The visitors and deacons who’d come from around the world to take part, and hoped to see the Pope, were left disappointed. Though they said they felt his presence. “It is what it is,” said one.

They know the Pope is an 88-year-old man who has spent the last few years assisted by a wheelchair and walking stick. Throughout his life he has been dogged by lung issues.

It leaves an almost philosophical mood ahead of what the coming days may bring.

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Doctors said on Friday that he was “not out of danger” and was expected to remain in hospital for at least another week.

They also warned that while he did not have sepsis, there was always a risk the infection could spread in his body.

Sepsis is a complication of an infection that can lead to organ failure and death.

Pope Francis has a history of respiratory illness, having lost part of one of his lungs to pleurisy as a young man. He also had an acute case of pneumonia in 2023.

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