The procedure took place May 14 at the University of Michigan with a patient who was already undergoing neurosurgery to treat epilepsy. The company’s technology was implanted and removed from the patient’s brain in about 20 minutes during that surgery.
Paradromics said the procedure demonstrated that its system can be safely implanted and record neural activity. It’s a major milestone for the nearly 10-year-old startup, as it marks the beginning of its next chapter as a clinical-stage company.
Once regulators give it the green light, Paradromics plans to kick off a clinical trial later this year that will study the long-term safety and use of its technology in humans.
“We’ve shown in sheep that our device is best in class from a data and longevity standpoint, and now we’ve also shown that it’s compatible with humans,” Paradromics founder and CEO Matt Angle told CNBC in an interview. “That’s really exciting and raises a lot of excitement for our upcoming clinical trial.”
A brain-computer interface, or BCI, is a system that deciphers brain signals and translates them into commands for external technologies. Paradromics’ system is called the Connexus Brain-Computer Interface, and the company says it will initially help patients with severe motor impairments such as paralysis speak through a computer.
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Paradromics’ BCI has not been cleared by the U.S. Food and Drug Administration, and it still has a long road ahead before it reaches commercialization.
But for Angle, who founded the company in 2015, the procedure in May was a success, and one that was years in the making.
“You do all of these steps, you validate the hardware, you have this really high degree of rational certainty that things are going to work,” he said, “but still emotionally when it works and when it happens the way you expected it to, it’s still very, very gratifying.”
Though Paradromics’ BCI has not been officially cleared for use by regulators, organizations like the University of Michigan can use new devices for research as long as they can demonstrate that there is not a significant risk to patients.
Dr. Oren Sagher, professor of neurosurgery at the University of Michigan, oversaw the traditional clinical component of the procedure in May. Dr. Matthew Willsey, assistant professor of neurosurgery and biomedical engineering at the University of Michigan, led the research component, including the placement of Paradromics’ device.
BCIs have been studied in academia for decades, and several other startups, including Elon Musk‘s Neuralink, are developing their own systems.
Paradromics’ Connexus Brain-Computer Interface.
Courtesy: Paradromics
“It’s absolutely thrilling,” Willsey said in an interview. “It’s motivating, and this is the kind of thing that helps me get up in the morning and go to work.”
Each company’s BCI is slightly different, but Paradromics is designing a BCI that can record brain activity at the level of individual neurons.
Angle compared this approach to placing microphones inside vs. outside a stadium. Inside a stadium, microphones would capture more detail, such as individual conversations. Outside a stadium, microphones would only capture the roar of the crowd, he said.
Other prominent BCI companies include Synchron, which is backed by Jeff Bezos and Bill Gates, and Precision Neuroscience. Both have implanted their systems in humans.
Paradromics has raised nearly $100 million as of February, according to PitchBook. The company announced a strategic partnership with Saudi Arabia’s Neom in February, but declined to disclose the investment amount.
“The last demonstration stuff has been shown, and we’re really excited about the clinical trial that’s coming up,” Angle said.
WATCH:Inside Paradromics, the Neuralink competitor hoping to commercialize brain implants before the end of the decade
People walk by a banner featuring the logo of Palantir Technologies (PLTR) at the New York Stock Exchange (NYSE) on the day of their initial public offering (IPO) in Manhattan, New York City, U.S., September 30, 2020.
Andrew Kelly | Reutersa
When Palantir hit the stock market in September 2020, there was a lot that could go wrong. The Covid pandemic was sweeping across the globe, society was in lockdown and markets were volatile.
Meanwhile, Palantir was operating at a loss while dealing with ongoing criticism over its government work, in particular with U.S. Customs and Immigration. And the company was going public through a direct listing rather than a traditional IPO.
At its opening price of $10 per share, Palantir was valued at $16.5 billion, down from its private market peak of $20.4 billion in 2015.
“It was the beginning of the pandemic, no one knew what was happening,” CFO David Glazer said in an interview. “The stock market wasn’t ripping, everyone wasn’t trying to go public, and we decided to go public as quickly as possible.”
Exactly five years later, Palantir has reached heights that would’ve been hard for even the biggest bulls to fathom.
The stock price has surged more than 1,700%, closing on Tuesday at $182.42 for a market cap of over $432 billion. That puts it among the 20 most-valuable U.S. companies, and above tech stalwarts like Cisco and IBM. Last year, Palantir joined the S&P 500, replacing American Airlines.
Quarterly revenue surpassed $1 billion for the first time last quarter, and is expected to reach $4.2 billion this year, according to analysts surveyed by LSEG, up almost sixfold from 2019. The company’s roster of customers grew from 125 in the first half of 2020 to 849 at the end of June. During that time, Palantir has added 1,500 full-time employees.
CEO Alex Karp, who founded the company in 2003 alongside notable investors like Peter Thiel and Joe Lonsdale, was exerting optimism on day one of Palantir’s life on the public market.
“We’ve reached a base where our company is very significant,” Karp, who holds a law degree from Stanford and PhD in neoclassical social theory from Goethe University in Frankfurt, Germany, told CNBC in an interview on listing day. “Being in the public space will help us with our clients and help us grow.”
Its dizzying ascent since then has perplexed Wall Street, which is unfamiliar with these kinds of multiples, especially for companies of this size.
Palantir trades for 226 times earnings over the next 12 months, with a forward revenue multiple of over 80. Those numbers dwarf even the multiples on Tesla, which trades for 194 times forward earnings and 14 times revenue over the next year.
In a report last month, Citron Research’s Andrew Left, a noted short-seller, called Palantir “detached from fundamentals and analysis.” When compared to OpenAI’s recent $500 billion valuation, he said Palantir should be priced at $40, or less than one-quarter of its current price, if it was assessed the same revenue multiple as the artificial intelligence startup.
“Karp and his team should be proud. But for investors, that’s where discipline kicks in,” Left wrote. “Comparison is the enemy of happiness, and when measured against true AI leaders, Palantir’s price already reflects success beyond its fundamentals.”
Karp, who doesn’t shy away from a dispute, recently told detractors to “exit” if they “don’t like the price.”
“We are going to be the most important software company in the world, and people will figure out what that’s valued over a long period of time,” Karp said on the day of the company’s NYSE debut.
Palantir declined to make Karp available for an interview.
Alex Karp, CEO of Palantir, attending the annual Allen & Co. Media and Technology Conference in Sun Valley, Idaho, on July 9, 2025.
David A. Grogan | CNBC
Valuation isn’t the only source of controversy. Critics have also raised concerns about how Palantir’s tools are being used by the likes of ICE and other government agencies.
Palantir was founded as a response to national security threats in the wake of 9/11. The company developed hefty software that it helped customize for clients to enable them to compile and analyze large data sets. On its website, Palantir says that it’s partnered with the U.S. Army since 2008, “embedding alongside users to design and deploy modern mission essential software solutions.”
Federal documents from April show that ICE paid Palantir $30 million to provide “real-time visibility” on people self-deporting. Earlier this year, the New York Times reported that Palantir is helping the Trump administration gather data on Americans.
In a blog post, Palantir called the reporting “reckless and irresponsible.” Karp said in a June interview with CNBC that Palantir was “not surveilling Americans.”
‘Not just about Israel’
The company has also faced backlash for providing technology to the Ukrainian and Israeli militaries.
Karp told CNBC in March 2024 that employees had left the company due to his public support of Israel, and that he expected more to leave. Palantir took out a full-page ad in The New York Times following the deadly Oct. 7 attack by Hamas the prior year that said the company “stands with Israel.”
“From my perspective, it’s not just about Israel,” Karp said in the CNBC interview. “It’s like, ‘Do you believe in the West? Do you believe the West has created a superior way of living?'”
Over the last five years, Palantir has scooped up big government deals against contractors like RTX and partnered with aerospace giants such as L3Harris and Boeing. Over the summer, the company landed a software and data contract with the Army worth up to $10 billion.
Karp has long been an unapologetic defender of Palantir’s business pursuits.
Originally headquartered in Palo Alto, California, Karp moved the company to Denver in 2020 as he grew increasingly disgruntled with what he viewed as Silicon Valley’s monoculture.
In a letter to investors ahead of its direct listing, Karp said, “the engineering elite” of Silicon Valley do not know “how society should be organized or what justice requires” and that the company shares “fewer and fewer of the technology sector’s values and commitments.”
While Palantir has been a standout performer on the market over the past five years, long-term investors had to weather some dark days along the way.
By the end of 2020, Palantir’s stock had jumped to $23.55, a gain of almost 136%. In Karp’s letter ahead of the direct listing, he asserted that “effective software can be essential to an organization’s survival” during times of crisis.
Skepticism started building in the second half of 2021. Early the following year, rising interest rates and soaring inflation pushed investors out of risky securities and into safer assets like bonds. Palantir shares lost two-thirds of their value in 2022, closing the year at $6.42, well below the direct listing price.
But November of that year brought with it the introduction of ChatGPT and a new era of AI that revived and redefined the tech industry.
Palantir launched its AI platform called AIP in April 2023. It was designed to help securely integrate large language models when dealing with sensitive data, making it much faster and more efficient for Palantir’s technology to pull in and analyze information.
The company has attributed much of its expansion in the commercial market to AIP. Government business still accounts for most of its revenue, but Palantir has attracted corporate clients such as Wendy’s and American Airlines.
Glazer said on the latest earnings call in August that the total contract value of bookings in the quarter soared 185% to $1.1 billion, with U.S. commercial revenue jumping 93% from a year earlier.
“AIP continues to drive existing customer expansion and new customer conversions in the U.S.,” Glazer said.
One customer the company cited was auto supplier Lear and a recent five-year partnership between the two. Palantir said that Lear uses AIP for help with “proactively managing their tariff exposure, automating multiple administrative workflows, and dynamically balancing their manufacturing lines.”
Palantir’s stock soared 341% last year and is up another 141% so far in 2025.
The AI is getting a lot of use in government, too.
In 2024, Palantir landed a contract to create AI-powered mobile ground stations able to collect data for soldiers using space sensors. In May of this year, the Pentagon lifted the company’s total ceiling for its Maven Smart Systems contract for AI capabilities to $1.3 billion.
Akash Jain, Palantir’s technology chief and president of its U.S. government business, said in an interview that AI has created a whole new set of risks, forcing the government to rethink how it uses commercial technologies.
“We’re perfectly positioned for the growth,” he said.
The Walt Disney Co. signage on the floor of the New York Stock Exchange (NYSE) in New York, US, on Wednesday, May 7, 2025.
Michael Nagle | Bloomberg | Getty Images
The Walt Disney Company sent a cease and desist letter to Character.AI last week, warning the artificial intelligence startup to stop using copyrighted characters without authorization, a Disney spokesperson confirmed to CNBC on Tuesday.
A spokesperson for Character.AI said it removed the characters mentioned in the letter, and that “it’s always up to rightsholders to decide how people may interact with their IP.”
The spokesperson acknowledged that while some characters on its platform are completely original creations, others are “inspired by existing characters that people love.”
“We want to partner with the industry and rightsholders to empower them to bring their characters to our platform,” the Character.AI spokesperson told CNBC. “Our goal is to give IP owners the tools to create controlled, engaging and revenue-generating experiences from deep fandom for their characters and stories, expanding their reach using our new, interactive format.”
The letter serves as the latest example of how media companies like Disney are working to protect their intellectual property during the AI boom.
Disney is already involved in an ongoing lawsuit against AI image creator Midjourney, alleging that the company improperly used and distributed AI-generated characters from movies like “Cars,” “Toy Story,” “Shrek,” “The Avengers” and others.
Character.AI allows users to create and interact with character-based chatbots. Google inked a $2.7 billion licensing deal with Character.AI and hired its founders in 2024, and the startup became embroiled in a wrongful death lawsuit that same year.
The family of Sewell Setzer III, a 14-year-old boy in Florida, alleged he committed suicide after he became addicted to talking with a number of AI chatbots on the app. One of the chatbots was named Daenerys Targaryen, or Dany, who is a character in the show “Game of Thrones,” according to the lawsuit.
Character.AI is not the only AI company that’s faced scrutiny over its approach to IP.
Earlier this month, a federal judge preliminarily approved Anthropic’s offer to pay $1.5 billion to settle a class action lawsuit with a group of authors, who claimed that the company had illegally downloaded their books and others from pirated databases.
If you are having suicidal thoughts or are in distress, contact the Suicide & Crisis Lifeline at 988 for support and assistance from a trained counselor.
Daniel Rausch, vice president of Alexa and Echo, announces the Echo Studio and Echo Dot Max during an Amazon event showcasing new products in New York City, U.S., September 30, 2025.
Kylie Cooper | Reuters
Amazon on Tuesday unveiled four new smart speakers and voice-activated displays that are revamped with Alexa+, its personal assistant that’s powered by generative artificial intelligence.
The company debuted the Echo Dot Max, a revamped version of its compact smart speaker, which costs $99.99. Amazon also unveiled a new Echo Show 8 and Echo Show 11, priced at $179.99 and $219.99, respectively.
There’s also a new version of the Echo Studio, a larger, higher-end model with a more powerful speaker, priced at $219.99.
All the devices are available for preorder on Tuesday, and users will get Alexa+ early access “out of the box,” Amazon said. The Echo Dot Max and Echo Studio ship Oct. 29, while the Echo Show 8 and Echo Show 11 ship Nov. 12.
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The devices were launched at Amazon’s fall hardware bonanza, held in New York. They’re the first batch of revamped products under the leadership of Panos Panay, a former Microsoft hardware leader who joined Amazon in 2023.
It’s also the first set of Amazon hardware to integrate the company’s long-awaited Alexa+, which debuted in February and has slowly rolled out in early access for some users.
“These are the most powerful Echo devices we have ever created,” Panay said on stage at the event. “Custom silicon, advanced sensors, our best microphones and sound, noise cancellation, understanding the user, faster than anything we’ve ever delivered before. They’re also beautifully designed to fade into the background.”
Alongside a revamped look, Amazon added new AZ3 and AZ3 Pro chips for edge processing to the devices, which are faster, more powerful and have “AI built right in,” said Daniel Rausch, the head of Amazon’s Alexa and Echo businesses.
Panos Panay, head of Amazon’s Devices and Services team, introduces Echo during an Amazon product event in the Manhattan borough of New York City on September 30, 2025. Amazon announced its next generation of Kindle, Ring, Blink, Fire TV, and Echo devices.
Charly Triballeau | Afp | Getty Images
The devices also feature a so-called Omnisense platform that gives Alexa “better contextual awareness,” Rausch said. It allows the Echo Show to be able to recognize users and serve up personalized insights, like an analysis of how they slept last night or alert users if they left their front door unlocked after midnight.
Amazon faces growing pressure to update its hardware and software for the generative AI age following the success of rivals such as OpenAI’s ChatGPT and Google’s Gemini. Meta also has its Ray-Ban Meta glasses, which use its Llama large language model to answer spoken questions from the user.
Amazon is also looking beyond Alexa or Echo smart speakers for opportunities in device growth.
The company in July confirmed it’s acquiring AI wearables startup Bee, which makes a wristband that can record and transcribe conversations.