The contest takes place less than a year before the Scottish parliament election, with the result potentially offering a snapshot of how the political landscape north of the border will look in 2026.
Campaigning has been heated, with Reform UK accused of running a “racist” ad on Facebook against Scottish Labour leader Anas Sarwar.
Reform UK leader Nigel Farage has continued to double down, accusing his rival of “sectarian politics”.
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In response, the Scottish Labour MSP has branded Mr Farage a “poisonous little man” and “chief clown”, while SNP leader and First Minister John Swinney said: “He poses a threat to our values and must be stopped.”
But who will come out on top following Thursday’s vote?
Here are the candidates vying for support:
Collette Bradley, Scottish Socialist Party
Image: Collette Bradley, Scottish Socialist Party. Pic: Scottish Socialist Party
Scottish Socialist Party candidate Collette Bradley told Sky News that locals she has met while out campaigning have been angry about “poverty, inequality and Labour’s attacks on welfare, our NHS and services”.
She added: “They have little faith in Labour or the SNP delivering change.
“We’ve offered hope with our unique policy of a socialist MSP who’ll remain on the average worker’s wage, keeping us firmly in step with constituents’ living conditions – we alone reject the corrupting influence of the £75,000 MSP salary.
“We’re offering concrete socialist alternatives to the miserable status quo – redistribution of wealth from the millionaires to the millions via progressive taxation.”
Ms Bradley said the party stands for a society built around the “needs of people, not profit”.
She added: “Ordinary lives can be transformed with measures like a £15-an-hour minimum wage; free public transport; and investment in jobs, wages, quality council housing, NHS, education, welfare and pensions.
“We urge voters to reject the continued failure of the political mainstream and be bolder in their demands by voting Scottish Socialist.”
Andy Brady, Scottish Family Party
Image: Andy Brady, Scottish Family Party. Pic: Scottish Family Party
Candidate Andy Brady told Sky News that Scottish Family Party policies and principles are “built upon honesty, integrity and a passion to see real change in our nation”.
He said: “My time spent speaking to the locals over the past several weeks has revealed a common response – people are fed up being let down.”
Mr Brady said there had been “failed promises” to help local businesses, to repair the roads, and to bring life to the town centres and high streets.
He said: “The general feeling is that communities are feeling jaded and frustrated.”
Urging voters to back the Scottish Family Party, he added: “We value the families, businesses and the education of our local communities and if we can support them, communities will flourish.”
Ross Lambie, Reform UK
Image: Ross Lambie, Reform UK. Pic: Reform UK
South Lanarkshire councillor Ross Lambie is hoping to bring Reform UK’s “turquoise tide” to Scotland.
If Mr Farage’s party wins, it will put Scotland’s first minister on notice ahead of Holyrood 2026.
Mr Lambie, who defected from the Scottish Conservatives, told Sky News: “It’s been refreshing spending the past five or so weeks out on the doors in Hamilton, Larkhall and Stonehouse.
“What’s been very clear is that people everywhere are fed up, angry and scunnered with the entire Scottish political establishment.
“They’re fed up with SNP, Tory and Labour lies and are looking for hope.
“Reform UK is offering people a chance of real and radical change by cutting tax, scrapping net zero, ending wokery and fighting for common sense.
“This is now a clear fight between the SNP and Reform – it’s that simple.”
Katy Loudon, Scottish National Party
Image: Katy Loudon, Scottish National Party. Pic: SNP
South Lanarkshire councillor Katy Loudon is hoping to retain the seat for the SNP.
The former teacher told Sky News she had been speaking to people across the region “about what matters to them”.
She said: “People understandably feel let down by Labour.”
Scottish Labour-run South Lanarkshire Council also intends to reduce its school transport provision, which Ms Loudon said will affect thousands of children.
Image: Ms Loudon and SNP leader John Swinney on the campaign trail in Hamilton. Pic: PA
She added: “The Labour Party has lost its way, Farage is on the rise as a result. With an invisible candidate, they’ve totally given up in this by-election.
“Meanwhile, the SNP is focusing on what matters to people and taking action to make things better – with record investment in our NHS, bringing back the winter fuel payment, scrapping peak rail fares and ending Labour’s two-child cap.
“Labour know they can’t win. Only the SNP can beat Farage on 5 June.”
Janice MacKay, UK Independence Party
Image: Janice MacKay, UK Independence Party. Pic: UKIP
UKIP candidate Janice MacKay told Sky News that her party would abolish the Scottish parliament if given the opportunity.
Speaking of “widespread disillusionment” amongst voters, she added: “UKIP offer something different.
“We wish to radically reduce the number of inadequate politicians in Scotland by abolishing altogether the Holyrood parliament.
“It is merely a glorified and expensive form of local authority. To that end, it is unnecessary.”
Ms MacKay believes the nation’s 32 local authorities should be given “strengthened powers”, with Westminster making the “main decisions” affecting the UK.
Ms MacKay added: “Were UKIP to win any seats in the Holyrood talking shop, we should donate 40% of our MSP salary to a Scottish veterans charity.”
Ann McGuinness, Scottish Green Party
Image: Ann McGuinness, Scottish Green Party. Pic: Scottish Green Party
Scottish Green Party candidate Ann McGuinness is the director of a charity which promotes rural connections and champions rural diversity.
The mother-of-two says her own lived experiences of poverty and disability provide her with “valuable insight” into the challenges faced by many whose voices are often unheard in the public discourse.
She has been described by her party as a “dedicated feminist and environmental justice campaigner”.
As well as promoting climate education, Ms McGuinness is also said to have a “strong track record of working across party lines to support women in politics”.
Ms McGuinness said: “Every vote for the Scottish Greens will be a positive vote for a fairer and greener Scotland and a brighter future for Hamilton, Larkhall and Stonehouse.
“If we are to build a truly just and green future, we need to empower every town and village and ensure that no one is left behind.”
Aisha Mir, Scottish Liberal Democrats
Image: Aisha Mir, Scottish Liberal Democrats. Pic: Scottish Liberal Democrats
Scottish Liberal Democrats candidate Aisha Mir told Sky News she has entered politics to “get things done”.
She added: “For too many people, it feels like nothing works anymore.
“The SNP have failed Scotland for 18 years. The Conservatives are lurching to extremes. Labour are already letting people down. Reform have no real solutions.
“I want to be a hard-working local champion who will put your priorities first.”
Ms Mir said her party offers a vision of Scotland “that is back to its best”.
She added: “A Scotland where people can see a GP and an NHS dentist in good time. A Scotland that once again gives our children a world-class education.
“A Scotland with a growing economy and growing businesses, where the government looks after your money and works with our neighbours.
“Vote Scottish Liberal Democrats for a candidate who is focused on what really matters to you.”
Richard Nelson, Scottish Conservative and Unionist Party
Image: Richard Nelson, Scottish Conservative and Unionist Party. Pic: Scottish Conservatives
Scottish Conservatives candidate Richard Nelson told Sky News he got into politics “to make a difference”.
The South Lanarkshire councillor and NHS worker said: “People across this constituency want politicians to be focused on what really matters to them rather than left-wing politicians focusing on their fringe obsessions.”
Image: Mr Nelson with Scottish Tory leader Russell Findlay. Pic: Scottish Conservatives
Mr Nelson said he has seen “first-hand as an NHS employee the damage the SNP have done to the health service during their 18 years in power”.
He added: “My wife disgracefully had to spend 50 hours on a trolley in A&E recently due to the SNP’s neglect of frontline care.
“If people in Hamilton, Larkhall and Stonehouse want to have an MSP who will stand up for those who just want politicians to show some common sense for a change, then you should vote for myself and the Scottish Conservatives on Thursday.”
Davy Russell, Scottish Labour Party
Image: Davy Russell, Scottish Labour Party. Pic: Scottish Labour Party
Scottish Labour candidate Davy Russell told Sky News he has seen “first-hand the damage the SNP has done” to the community after almost two decades in power.
He said: “Throughout this campaign, I have been speaking to people who are feeling abandoned by this SNP government.
“People are languishing on long NHS waiting lists, worried about the state of our schools, and sick of seeing our high streets decline – but this is not as good as it gets.
“The SNP don’t deserve to win here, and the divisive politics of Reform cannot win. This by-election is a straight choice between more of the same SNP failure or a new direction with Scottish Labour.”
Image: Scottish Labour leader Anas Sarwar, left, with Mr Russell. Pic: PA
Mr Russell vowed to “fight tirelessly for the community I love” if he wins.
He added: “I will stand firmly against the downgrading of the Wishaw Neonatal Unit, campaign for an end to SNP cuts to our local services, and demand real action to tackle the crisis in our NHS.
“This is a chance to not only select a local champion for Hamilton, Larkhall and Stonehouse, but to begin to chart a new direction for the whole of Scotland.”
Marc Wilkinson, Independent
Image: Marc Wilkinson, Independent. Pic: Marc Wilkinson
Marc Wilkinson, a pizza shop owner from the Scottish capital, is the leader of the Edinburgh People party.
The businessman is also behind the South Scotland People party, which is part of a bid to establish regional parties across the nation for the Holyrood list vote next year.
Mr Wilkinson’s aim is for “the people of Scotland to choose to vote for themselves”.
Pledging to take instruction directly from the constituents if he were to win the upcoming by-election, he added: “Elect me and you will be my boss. Don’t choose protest. Choose progress.”
Many Labour MPs have been left shellshocked after the chaotic political self-sabotage of the past week.
Bafflement, anger, disappointment, and sheer frustration are all on relatively open display at the circular firing squad which seems to have surrounded the prime minister.
The botched effort to flush out backroom plotters and force Wes Streeting to declare his loyalty ahead of the budget has instead led even previously loyal Starmerites to predict the PM could be forced out of office before the local elections in May.
“We have so many councillors coming up for election across the country,” one says, “and at the moment it looks like they’re going to be wiped out. That’s our base – we just can’t afford to lose them. I like Keir [Starmer] but there’s only a limited window left to turn things around. There’s a real question of urgency.”
Another criticised a “boys club” at No 10 who they claimed have “undermined” the prime minister and “forgotten they’re meant to be serving the British people.”
There’s clearly widespread muttering about what to do next – and even a degree of enviousness at the lack of a regicidal 1922 committee mechanism, as enjoyed by the Tories.
“Leadership speculation is destabilising,” one said. “But there’s really no obvious strategy. Andy Burnham isn’t even an MP. You’d need a stalking horse candidate and we don’t have one. There’s no 1922. It’s very messy.”
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0:54
Starmer’s faithfuls are ‘losing faith’
Others are gunning for the chancellor after months of careful pitch-rolling for manifesto-breaching tax rises in the budget were ripped up overnight.
“Her career is toast,” one told me. “Rachel has just lost all credibility. She screwed up on the manifesto. She screwed up on the last two fiscal events, costing the party huge amounts of support and leaving the economy stagnating.
“Having now walked everyone up the mountain of tax rises and made us vote to support them on the opposition day debate two days ago, she’s now worried her job is at risk and has bottled it.
“Talk to any major business or investor and they are holding off investing in the UK until it is clear what the UK’s tax policy is going to be, putting us in a situation where the chancellor is going to have to go through this all over again in six months – which just means no real economic growth for another six months.”
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After less than 18 months in office, the government is stuck in a political morass largely of its own making.
Treasury sources have belatedly argued that the chancellor’s pre-budget change of heart on income tax is down to better-than-expected economic forecasts from the Office for Budget Responsibility.
That should be a cause of celebration. The question is whether she and the PM are now too damaged to make that case to the country – and rescue their benighted prospects.
We’re told that Shabana Mahmood, the still new home secretary, is “a woman in a hurry”.
She’s been in the job for 73 days – and is now announcing “the most sweeping reforms to tackle illegal migration in modern times” – effectively since the Second World War.
Her language is not just tough – it’s radical. Not what you’d have expected to hear from a Labour home secretary even just a few months ago.
“Illegal migration”, she believes, “is tearing our country apart. The crisis at our borders is out of control”.
Her team argues that those never-ending images of people crossing the Channel in small boats have led to a complete loss of faith in the government’s ability to take any action at all – let alone deliver on its promises.
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1:29
‘Illegal migration is creating division across our country’.
The political reality is that successive failures of Tory and Labour ministers have fuelled the inexorable rise of Reform.
But speaking to Sir Trevor Phillips on Sky News, Ms Mahmood firmly hit back at suggestions today’s announcements are pandering to a racist narrative from the far right.
“It’s not right-wing talking points or fake news or misinformation that is suggesting that we’ve got a problem,” she said.
“I know, because I have now seen this system inside out. It is a broken system. We have a genuine problem to fix. People are angry about something that is real.
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1:09
Trevor’s takeaway
“It is my job, therefore, to think of a proper solution to this very real problem, to do so in line with my values as a Labour politician, but also as a British citizen, and to have solutions that work so that I can unite a divided country.”
There are many striking elements to this.
While she’s not been in the job for all that long, her government has been in power for 16 months. Her own press release highlights that over the past full calendar year asylum claims here have gone up by 18% – compared with a drop of 13% elsewhere in the EU.
The UK, she argues, has become a “golden ticket” for asylum seekers due to “far more generous terms” than other countries in Europe.
While she politely insists that her predecessor’s policies – the one in one out deal with France, closer partnership with law enforcement across Europe – are beginning to take effect, the message is clear. No one in office before Shabana has had the stomach to grasp the nettle.
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4:42
Inside Europe’s people smuggling industry
The Home Office is determined to present their boss as the new hard woman of British politics.
In a bleak warning to those in her party who will be deeply uncomfortable with this unflinching approach, we’re told she believes this is “the last chance for decent, moderate politics”.
“If these moderate forces fail, something darker will follow…. if you don’t like this, you won’t like what follows me.”
That’s a clear reference to the anti-asylum policies of Reform and the Conservatives, who are pledging to leave the European Convention on Human Rights and deport all illegal arrivals.
Both parties have responded by effectively claiming they don’t trust Labour to deliver on this, given they believe the government has lost control of our borders and overseen a surge in asylum claims.
That much Ms Mahmood herself has already acknowledged.
It’s unusual to hear a Conservative shadow minister like Chris Philp responding to a government announcement by claiming they will support the “sensible steps” the Home Office is making.
Unsurprisingly, he went on to belittle her ideas as “very small steps” combined with “gimmicks” – but the main thrust of his critique was that Labour lacks the authority to push these kinds of measures through parliament, given the likely opposition from their own left wingers.
It’s a fair point – but the lack of fundamental disagreement highlights the threat these plans pose to her opponents.
If the government looks like it might actually succeed in bringing down the numbers – and of course that’s a colossal if – Ms Mahmood will effectively have outflanked and neutralised much of the threat from both the Tories and Reform.
That’s why she’s so keen to mention her Danish inspiration – a centre-left government which managed to see off the threat from right-wing parties through its tough approach to migration, without having to leave the ECHR.
The Home Office is planning further announcements on new safe and legal routes.
But refugee charities have described the new measures as harsh, claiming they will scapegoat genuine refugees, fail to integrate them into society, and fail to function as a deterrent either.
There will surely be an almighty internal row among Labour MPs about the principle of ripping up the post-war settlement for refugees.
For a government floundering after the political chaos of the last few weeks and months, Ms Mahmood is a voice of certainty and confidence.
At a moment of such intense backroom debate over the party’s future direction, it’s hard to avoid seeing her performance this weekend as a starting pitch for the leadership.
Sir Keir Starmer and Rachel Reeves have scrapped plans to break their manifesto pledge and raise income tax rates in a massive U-turn less than two weeks from the budget.
I understand Downing Street has backed down amid fears about the backlash from disgruntled MPs and voters.
The Treasury and Number 10 declined to comment.
The decision is a massive about-turn. In a news conference last week, the chancellor appeared to pave the way for manifesto-breaking tax rises in the budget on 26 November.
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3:53
‘Aren’t you making a mockery of voters?’
The decision to backtrack was communicated to the Office for Budget Responsibility on Wednesday in a submission of “major measures”, according to the Financial Times.
The chancellor will now have to fill an estimated £30bn black hole with a series of narrower tax-raising measures and is also expected to freeze income tax thresholds for another two years beyond 2028, which should raise about £8bn.
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Conservative leader Kemi Badenoch said: “Only the Conservatives have fought Labour off their tax-raising plans.
“But one retreat doesn’t fix a budget built on broken promises. Reeves must guarantee no new taxes on work, businesses, homes, or pensions – and she should go further by abolishing stamp duty.”
How did we get here?
For weeks, the government has been working up options to break the manifesto pledge not to raise income tax, national insurance or VAT on working people.
I was told only this week the option being worked up was to do a combination of tax rises and action on the two-child benefit cap in order for the prime minister to be able to argue that in breaking his manifesto pledges, he is trying his hardest to protect the poorest in society and those “working people” he has spoken of so endlessly.
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13:06
Ed Conway on the chancellor’s options
But days ago, officials and ministers were working on a proposal to lift the basic rate of income tax – perhaps by 2p – and then simultaneously cut national insurance contributions for those on the basic rate of income tax (those who earn up to £50,000 a year).
That way the chancellor can raise several billion in tax from those with the “broadest shoulders” – higher-rate taxpayers and pensioners or landlords, while also trying to protect “working people” earning salaries under £50,000 a year.
The chancellor was also going to take action on the two-child benefit cap in response to growing demand from the party to take action on child poverty. It is unclear whether those plans will now be shelved given the U-turn on income tax.
The change of plan comes after the prime minister found himself engulfed in a leadership crisis after his allies warned rivals that he would fight any attempted post-budget coup.
It triggered a briefing war between Wes Streeting and anonymous Starmer allies attacking the health secretary as the chief traitor.
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3:26
Wes Streeting: Faithful or traitor? Beth Rigby’s take
But the saga has further damaged Sir Keir and increased concerns among MPs about his suitability to lead Labour into the next general election.
Insiders clearly concluded that the ill mood in the party, coupled with the recent hits to the PM’s political capital, makes manifesto-breaking tax rises simply too risky right now.
But it also adds to a sense of chaos, given the chancellor publicly pitch-rolled tax rises in last week’s news conference.