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Regime change in Iran is “unacceptable” and the assassination of the country’s supreme leader would “open the Pandora’s box”, the Kremlin has said.

In a rare interview with a foreign media organisation, Kremlin spokesman Dmitry Peskov told Sky News that Russia would react “very negatively” if Ayatollah Ali Khamenei was killed.

The comments came as US President Donald Trump said he will decide within two weeks whether America will join Israel’s military campaign against Tehran, after earlier speculating on social media about killing the Iranian leader.

Dmitry Peskov
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Dmitry Peskov speaks to Sky News

“The situation is extremely tense and is dangerous not only for the region but globally,” Mr Peskov said in an interview at the Constantine Palace in Saint Petersburg.

“An enlargement of the composition of the participants of the conflict is potentially even more dangerous.

“It will lead only to another circle of confrontation and escalation of tension in the region.”

Supreme Leader Ayatollah Ali Khamenei and Russian President Vladimir Putin meeting in Tehran, Iran, Tuesday, July 19, 2022. AP
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Putin and Khamenei meeting in Tehran in 2022. Pic: AP

They are the Kremlin’s strongest comments yet regarding the Israel-Iran conflict, which has stoked fears in Moscow that it could be on the verge of losing its closest ally in the Middle East.

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Russia has deepened its ties with Iran since invading Ukraine, and the two countries signed a strategic partnership in January.

“[Regime change in Iran] is unimaginable. It should be unacceptable, even talking about that should be unacceptable for everyone,” Mr Peskov said, in a thinly veiled reference to Washington.

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How will Russia react to US joining Israel?

But Mr Peskov refused to be drawn on what action Russia would take if Khamenei was killed, saying instead it would trigger action “from inside Iran”.

“It would lead to the birth of extremist moods inside Iran and those who are speaking about [killing Khamenei], they should keep it in mind. They will open the Pandora’s box.”

Vladimir Putin’s offers to mediate an end to the conflict have so far been rejected by Mr Trump, who said on Wednesday that he told the Russian president to “mediate your own [conflict]”, in reference to Russia’s war against Ukraine.

Mr Peskov denied the American president’s words were insulting, adding: “Everyone has a different language.

“President Trump has his own unique way of speaking and his unique language. We are quite tolerant and expect everyone to be tolerant of us.”

President Donald Trump meets with members of the Juventus soccer club in the Oval Office of the White House, Wednesday, June 18, 2025, in Washington. (AP Photo/Alex Brandon)
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Trump’s attempts to broker peace between Ukraine and Russia have so far not been fruitful. Pic: AP

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The Trump administration’s own mediation efforts to end the war in Ukraine have failed to yield any major breakthroughs, despite two rounds of direct talks between Moscow and Kyiv.

Moscow has stepped up its aerial bombardment of Ukraine in recent weeks and continues to reject Volodymyr Zelenskyy’s calls for a 30-day ceasefire.

“Now we have a strategic advantage. Why should we lose it? We are not going to lose it. We are going further. We’re advancing and we’ll continue to advance,” Mr Peskov said.

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Russia has previously said it would only commit to a ceasefire if Kyiv stops receiving foreign military support, fearing that a pause in the fighting would offer Ukraine a chance to rearm and regroup its forces.

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Asked if Moscow could commit to not using a ceasefire in the same way, Mr Peskov said: “A ceasefire is a ceasefire, and you stop.

“But America is not saying that ‘we’ll quit any supplies’. Britain is not saying that as well. France is not saying that as well. This is the problem.”

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Contact with two hostages ‘lost’ during Israeli operations in Gaza, Hamas’s armed group says

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Contact with two hostages 'lost' during Israeli operations in Gaza, Hamas's armed group says

Hamas’s armed group has claimed it has lost contact with two hostages as a result of Israel’s operations in Gaza – after it called on air deployments to be stopped for 24 hours.

In a statement, Hamas’s armed al-Qassam Brigades said it had demanded that Israel halt air sorties for 24 hours, starting at 6pm, in part of Gaza City, to remove the hostages from danger.

It comes a day before Israeli Prime Minister Benjamin Netanyahu is due to meet US President Donald Trump and as the number of those killed in Gaza surpasses the 66,000 mark, according to the enclave’s Hamas-run health ministry.

Its figure does not differentiate between civilians and fighters.

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Volunteer nurse’s video diary of Gaza horrors

A total of 48 hostages are still being held captive by Hamas, the militant group which rules Gaza, with about 20 believed by Israel to still be alive. A total of 251 hostages were taken on 7 October 2023, when Hamas launched an unprecedented attack on Israel which killed 1,200 people.

Situation on the ground

In Gaza, a war-torn enclave where famine has been declared in some areas and where Israel has been accused of committing acts of genocide – which it has repeatedly denied – the almost two-year war raged on.

On Sunday, the number of those killed rose to at least 21 as five people were killed in an airstrike in the Al Naser area, local health authorities said, while medics reported 16 more deaths in strikes on houses in central Gaza.

The Civil Emergency Service in Gaza said late on Saturday that Israel had denied 73 requests, sent via international
organisations, to rescue injured Palestinians in Gaza City.

Israeli authorities had no immediate comment. The military earlier said forces were expanding operations in the city and
that five militants firing an anti-tank missile towards Israeli troops had been killed by the Israeli air force.

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‘We will get it done’

In Monday’s White House meeting, President Trump is expected to share a new 21-point proposal for an immediate ceasefire.

His proposal would include the release of all hostages within 48 hours and a gradual withdrawal of Israeli forces from the Palestinian enclave, according to three Arab officials briefed on the plan, the PA news agency reports.

A Hamas official said the group was briefed on the plan but has yet to receive an official offer from Egyptian and Qatari mediators. Hamas has said it is ready to “study any proposals positively and responsibly”.

Mr Trump, who has been one of Israel’s greatest allies, said on Sunday there is “a real chance for greatness in the Middle East”.

It is unclear, however, what Mr Trump was specifically referring to.

He said in a Truth Social post: “We have a real chance for Greatness in the Middle East. All are on board for something special, first time ever. We will get it done.”

On Friday – the same day a video of diplomats walking out on Mr Netanyahu during his address to the United Nations went viral – Mr Trump said he believed the US had reached a deal on easing fighting in Gaza, saying it “will get the hostages back” and “end the war”.

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Diplomats walk out as Israeli PM speaks at UN

“I think we maybe have a deal on Gaza, very close to a deal on Gaza,” the US president told reporters on the White House lawn as he was leaving to attend the Ryder Cup.

Mr Trump has repeatedly claimed an agreement to end the war was imminent, only for nothing to materialise.

Weeks ago, he said: “I think we’re going to have a deal on Gaza very soon.”

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‘I’m not so careful with what I say’ – is Trump feeling more invincible than ever?

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'I'm not so careful with what I say' - is Trump feeling more invincible than ever?

It was one sentence among the many words Donald Trump spoke this week that caught my attention.

Midway through a jaw-dropping news conference where he sensationally claimed to have “found an answer on autism”, he said: “Bobby (Kennedy) wants to be very careful with what he says, but I’m not so careful with what I say.”

The US president has gone from pushing the envelope to completely unfiltered.

Last Sunday, moments after Charlie Kirk‘s widow Erika had publicly forgiven her husband’s killer, Mr Trump told the congregation at his memorial service that he “hates his opponents”.

President Donald Trump embraces Charlie Kirk's widow Erika. Pic: AP
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President Donald Trump embraces Charlie Kirk’s widow Erika. Pic: AP

Twenty-four hours later, he drew fierce rebuke from medical experts by linking the use of Tylenol (paracetamol) during pregnancy to increased risk of autism.

The president treats professional disapproval not as a liability but as evidence of authenticity, fuelling the aura that he is a challenger of conventions.

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‘Paracetamol use in pregnancy perfectly safe’

On Tuesday, he went to the United Nations, where his frustrations over a stalled escalator and teleprompter failure were the prelude to the most combative address.

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“I’m really good at this stuff. Your countries are going to hell,” he told his audience, deriding Europe’s approach to immigration as a “failed experiment of open borders”.

Mr Trump addresses the UN General Assembly in New York. Pic: Reuters
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Mr Trump addresses the UN General Assembly in New York. Pic: Reuters

Then came a U-turn on Ukraine, suggesting the country could win back all the land it has lost to Russia.

Most politicians would be punished for inconsistency, but Mr Trump recasts this as strategic genius – framing himself as dictating the terms.

It is hard to keep track when his expressed hopes for peace in Ukraine and Gaza are peppered with social media posts condemning the return of Jimmy Kimmel to late-night television.

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Trump’s major shift in Ukraine policy

Perhaps most striking of all is his reaction to the indictment of James Comey, the FBI director he fired during his first term.

In theory, this should raise questions about the president’s past conflicts with law enforcement, but he frames it as vindication, proof that his enemies fall while he survives.

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Ex-FBI chief: ‘Costs to standing up to Trump’

Mr Trump has spent much of his political career cultivating an image of a man above the normal consequences of politics, law or diplomacy, but he appears to feel more invincible than ever.

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From funerals to world summits, world peace to public health, he projects the same image: rules are for others.

It is the politics of the untouchable.

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Russia launches massive attack on Kyiv – as Poland scrambles jets and closes airspace

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Russia launches massive attack on Kyiv - as Poland scrambles jets and closes airspace

Russia has launched a massive drone attack on Ukraine’s capital this morning, injuring at least six people, Kyiv’s military administration has said.

Poland closed the airspace near two of its southeastern cities, Lublin and Rzeszow, as its air force scrambled jets in response to Russia’s attack on Kyiv.

Drones flew over Kyiv and anti-aircraft fire rang out through the night in what independent monitors said was one of the biggest strikes on the city since the Ukraine war began in February 2022.

The attack started at around 6am local time and many regions across the country are under air raid alert.

Some residents have fled to metro stations deep underground for safety as the attack continues.

Poland said it had closed its airspace near the two cities until at least 4am GMT due to “unplanned military activity related to ensuring state security”, flight tracking service Flightradar24 said.

“In connection with the activity of the Russian Federation’s long-range aviation carrying out strikes on the territory of
Ukraine, Polish and allied aircraft have begun operating in our airspace,” the military said in a post on X.

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It described the actions as preventive and aimed at securing airspace and protecting citizens.

It comes as Russian foreign minister Sergei Lavrov was expected to address allegations made against Moscow that it has violated the airspace of several of its neighbours in recent weeks, as he spoke in New York at the 80th UN General Assembly.

A NATO air defence mission was recently carried out over Poland in response to “unprecedented” Russian drone incursions above the country.

During his address, Mr Lavrov, who has been Russia’s foreign minister for 21 years, says his country had no intention of attacking any NATO or EU member state but warned of a “decisive response” if any “aggression” was directed towards Moscow.

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