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Cervical cancer rates are almost 90% lower in women vaccinated against HPV, a new study has found.

Women offered the vaccine between the ages of 12 and 13 were found to have cancer rates 87% lower than in previous generations, according to a study published in The Lancet.

Researchers also found a reduction of 62% in women vaccinated between ages 14 and 16.

Scotland introduced its national HPV immunisation programme for girls aged 12 to 13 in 2008
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England began rolling out its HPV vaccination programme in 2008

The first generation of women, who were offered “catch-up” jabs aged between 16 and 18, were found to have a 34% reduction in cervical cancer rates.

Professor Peter Sasieni, from King’s College London and one of the authors of the paper, told Sky News some of the results were “almost too good to be true”.

“Everything is on target to be preventing essentially all cancers from HPV 16 and 18 in vaccinated women,” he said.

He said there was also “some cross-protection” for other cancers caused by the human papillomavirus and “some protection, although much less, to women of the same age who are not actually vaccinated”.

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He continued: “There is a lot of vaccine hesitancy going on these days.

“People who are opposed to these vaccines can no longer say this vaccine doesn’t prevent cancer because this makes it absolutely clear it is having a dramatic effect on cervical cancer incidents.”

With COVID-19 vaccination now taking place in schools, he said there are pressures to move HPV jabs from the autumn to the summer term.

“We need to think about the impact that will have,” he said.

“People don’t come in because they are revising, or they only come in for exams. So to get the same uptake of the vaccine will be challenging – as I am sure it has been challenging the last year and a half because of COVID.”

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HPV vaccination has been introduced in 100 countries as part of efforts by the World Health Organisation (WHO) to eliminate cervical cancer.

It is a common sexually transmitted infection, with some types being linked to cervical cancer in women and head and neck cancer in men.

The English HPV vaccination programme was introduced in 2008, with vaccines given to women aged between 12 and 13 and “catch-up” jabs offered to older age groups up to the age of 18.

England initially used a bivalent vaccine, which protects against the two most common types of HPV, responsible for approximately 70% to 80% of all cervical cancers. Since September 2012, the quadrivalent vaccine Gardasil has been used instead.

The study looked at the population-based cancer registry data between January 2006 and June 2019 for seven cohorts of women, aged between 20 and 64.

Teenage boys aged 12 and 13 will be vaccinated against the HPV viruses from September
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Women offered the vaccine between the ages of 12 and 13 have an 87% reduction in cancer rates

During that time frame, 28,000 diagnoses of cervical cancer and 300,000 diagnoses of non-invasive cervical carcinoma (CIN3) in total were recorded in England.

In the three vaccinated cohorts, there were just 638 cases of cervical cancers and 18,662 cases of CIN3 compared to the non-vaccinated population.

Prof Sasieni said cases in young women were “very traumatic on everyone”.

“When talking to colleagues who treat women, they always remember the young ones and sometimes it is very aggressive and they can’t help that much,” he said.

One of the benefits of such an effective vaccine, he said, could mean women require less cervical screening, adding: “It doesn’t make sense to say you need to continue screening in the same way.”

The vaccine is expected to prevent 64,000 cervical cancers and almost 50,000 other cancers by 2058
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In the three vaccinated cohorts, there were around 450 fewer cases of cervical cancers

But he said until the policy was changed, “the last thing we want is for women to think, I have been vaccinated so I don’t need to attend my screening – because that could have really serious consequences”.

The authors of the study did acknowledge some limitations – principally that cervical cancer diagnosis is rare in young women. Because the vaccinated populations are still young, the authors also stressed this means that it is still too early to assess the full impact of HPV immunisation on cervical cancer rates.

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Specialist teams and online investigators deployed across England and Wales to tackle ‘national emergency’ of violence against women and girls

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Specialist teams and online investigators deployed across England and Wales to tackle 'national emergency' of violence against women and girls

Specialist investigation teams for rape and sexual offences are to be created across England and Wales as the Home Secretary declares violence against women and girls a “national emergency”.

Shabana Mahmood said the dedicated units will be in place across every force by 2029 as part of Labour’s violence against women and girls (VAWG) strategy due to be launched later this week.

The use of Domestic Abuse Protection Orders (DAPOs), which had been trialled in several areas, will also be rolled out across England and Wales. They are designed to target abusers by imposing curfews, electronic tags and exclusion zones.

The orders cover all forms of domestic abuse, including economic abuse, coercive and controlling behaviour, stalking and ‘honour’-based abuse. Breaching the terms can carry a prison term of up to 5 years.

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Govt ‘thinking again’ on abuse strategy

Nearly £2m will also be spent funding a network of officers to target offenders operating within the online space.

Teams will use covert and intelligence techniques to tackle violence against women and girls via apps and websites.

A similar undercover network funded by the Home Office to examine child sexual abuse has arrested over 1,700 perpetrators.

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Abuse is ‘national emergency’

Home Secretary Shabana Mahmood said in a statement: “This government has declared violence against women and girls a national emergency.

“For too long, these crimes have been considered a fact of life. That’s not good enough. We will halve it in a decade.

“Today we announce a range of measures to bear down on abusers, stopping them in their tracks. Rapists, sex offenders and abusers will have nowhere to hide.”

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Angiolini Inquiry: Recommendations are ‘not difficult’

The target to halve violence against women and girls in a decade is a Labour manifesto pledge.

The government said the measures build on existing policy, including facial recognition technology to identify offenders, improving protections for stalking victims, making strangulation a criminal offence and establishing domestic abuse specialists in 999 control rooms.

Read more from Sky News:
Demands for violence and abuse reforms
Women still feel unsafe on streets
Minister ‘clarifies’ violence strategy

Labour has ‘failed women’

But the Conservatives said Labour had “failed women” and “broken its promises” by delaying the publication of the violence against women and girls strategy.

Shadow Home Secretary, Chris Philp, said that Labour “shrinks from uncomfortable truths, voting against tougher sentences and presiding over falling sex-offender convictions. At every turn, Labour has failed women.”

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UK has seen longest period without migrants arriving on small boats since 2018, figures show

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UK has seen longest period without migrants arriving on small boats since 2018, figures show

There have been no migrant arrivals in small boats crossing the Channel for 28 days, according to Home Office figures.

The last recorded arrivals were on 14 November, making it the longest uninterrupted run since autumn 2018 after no reported arrivals on Friday.

However, a number of Border Force vessels were active in the English Channel on Saturday morning, indicating that there may be arrivals today.

So far, 39,292 people have crossed to the UK aboard small boats this year – already more than any other year except 2022.

The record that year was set at 45,774 arrivals.

It comes as the government has stepped up efforts in recent months to deter people from risking their lives crossing the Channel – but measures are not expected to have an impact until next year.

Debris of a small boat used by people thought to be migrants to cross the Channel lays amongst the sand dunes in Gravelines, France. Pic: PA
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Debris of a small boat used by people thought to be migrants to cross the Channel lays amongst the sand dunes in Gravelines, France. Pic: PA

December is normally one of the quietest for Channel crossings, with a combination of poor visibility, low temperatures, less daylight and stormy weather making the perilous journey more difficult.

The most arrivals recorded in the month of December is 3,254, in 2024.

Deputy Prime Minister David Lammy met with ministers from other European countries this week as discussions over possible reform to the European Convention on Human Rights (ECHR) continue.

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France agrees to start intercepting small boats

The issue of small boat arrivals – a very small percentage of overall UK immigration – has become a salient issue in British politics in recent years.

Last month, French maritime police announced they would soon be able to intercept boats in the English Channel.

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King reveals ‘good news’ in his battle with cancer and urges people to get checked

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King reveals 'good news' in his battle with cancer and urges people to get checked

The King has shared in a television address that, thanks to early diagnosis, his cancer treatment can be reduced in the new year.

In a televised address, Charles said his “good news” was “thanks to early diagnosis, effective intervention and adherence to doctors’ orders”.

“This milestone is both a personal blessing and a testimony to the remarkable advances that have been made in cancer care in recent years,” he added.

“Testimony that I hope may give encouragement to the 50% of us who will be diagnosed with the illness at some point in our lives.”

The King announced in February 2024 that he had been diagnosed with cancer and was beginning treatment.

The monarch postponed all public-facing engagements, but continued with his duties as head of state behind palace walls, conducting audiences and Privy Council meetings.

He returned to public duties in April last year and visited University College Hospital Macmillan Cancer Centre in central London with the Queen and discussed his “shock” at being diagnosed when he spoke to a fellow cancer patient.

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Sources suggested last December his treatment would continue in 2025 and was “moving in a positive direction”.

The King began returning to public duties in April last year. File pic: PA
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The King began returning to public duties in April last year. File pic: PA

The King has chosen not to reveal what kind of cancer he has been treated for. Palace sources have partly put that down to the fact that he doesn’t want one type of cancer to appear more significant or attract more attention than others.

In a statement after the speech aired, a Buckingham Palace spokesperson said: “His Majesty has responded exceptionally well to treatment and his doctors advise that ongoing measures will now move into a precautionary phase.”

Sir Keir Starmer praised the video message as “a powerful message,” and said: “I know I speak for the entire country when I say how glad I am that his cancer treatment will be reduced in the new year.

“Early cancer screening saves lives.”

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Watch: King Charles gives update on treatment

Early detection can give ‘the precious gift of hope’

His message on Friday was broadcast at 8pm in support of Stand Up To Cancer, a joint campaign by Cancer Research UK and Channel 4.

In an appeal to people to get screened for the disease early, the King said: “I know from my own experience that a cancer diagnosis can feel overwhelming.

“Yet I also know that early detection is the key that can transform treatment journeys, giving invaluable time to medical teams – and, to their patients, the precious gift of hope. These are gifts we can all help deliver.”

Charles noted that “at least nine million people in our country are not up to date with the cancer screenings available to them,” adding: “That is at least nine million opportunities for early diagnosis being missed.

“The statistics speak with stark clarity. To take just one example: When bowel cancer is caught at the earliest stage, around nine in ten people survive for at least five years.

“When diagnosed late, that falls to just one in ten. Early diagnosis quite simply saves lives.”

after months of uncertainty, some relief and reassurance for the King

This is a rare but positive update. The King in his own words speaking about his cancer.

And it’s good news.

Since his diagnosis, he’s received weekly treatment. His work schedule has had to fit around the appointments. And while it’s not stopping, it is being significantly reduced.

He’s responded well, and his recovery has reached, we understand, a very positive stage.

The King’s decision to speak publicly and so personally is unusual.

He has deliberately chosen the moment, supporting the high-profile Stand Up To Cancer campaign, and the launch of a national online screening checker.

It still hasn’t been revealed what kind of cancer he has. And there’s a reason – firstly, it’s private information.

But more importantly, the King knows the power of sharing his story. And with it, the potential to support the wider cancer community.

We are once again seeing a candid openness from the Royal Family. Earlier this year, the Princess of Wales discussed the ups and downs of her cancer journey.

These moments signal a shift towards greater transparency on matters the Royal Family once kept entirely private.

For millions facing cancer, the King’s update is empathy and encouragement from someone who understands.

And after months of uncertainty, for the King himself, some relief and reassurance.

Minor inconvenience of screening ‘a small price to pay’

The King acknowledged that people often avoid screening “because they imagine it may be frightening, embarrassing or uncomfortable”. But, he added: “If and when they do finally take up their invitation, they are glad they took part.

“A few moments of minor inconvenience are a small price to pay for the reassurance that comes for most people when they are either told either they don’t need further tests, or, for some, are given the chance to enable early detection, with the life-saving intervention that can follow.”

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Giving his “most heartfelt thanks” to doctors, nurses, researchers and charity workers, the King added: “As I have observed before, the darkest moments of illness can be illuminated by the greatest compassion. But compassion must be paired with action.

“This December, as we gather to reflect on the year past, I pray that we can each pledge, as part of our resolutions for the year ahead, to play our part in helping to catch cancer early.

“Your life – or the life of someone you love – may depend upon it.”

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