Bodycam footage of the altercation is expected to be released later on Friday evening.
His family said the “very horrific” video showed officers savagely beating the FedEx worker for three minutes in an assault their lawyers likened to the Los Angeles police attack on motorist Rodney King in 1991.
Five sacked officers, who are all black, have been charged with second-degree murder and other crimes, including assault, kidnapping, official misconduct and official oppression, over Mr Nichols’s death.
Civil rights lawyer Ben Crump, who is representing his family, said when the public watches the footage they will see him calling out for his mother.
He said: “When you all see this video, you’re going to see Tyre Nichols calling out for his mum.
“He calls out three times for his mother. His last words on this earth are, ‘mum, mum, mum’. He’s screaming for her. When you think about that kidnapping charge, he said ‘I just want to go home’.”
“It’s a traffic stop for God’s sake. A simple traffic stop.”
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Mr Nichols’s mother, RowVaughn Wells, told reporters: “For a mother to know their child was calling them in their need and I wasn’t there for him. Do you know how I feel right now? Because I wasn’t there for my son.”
Ms Wells recalled she had “a really bad pain in my stomach” and once she found out what happened she realised “that was my son’s pain that I was feeling”.
“For me to find out my son was calling my name, you have no clue how I feel right now,” she added, struggling to hold back tears.
She also said she had not yet seen the video but urged anyone with children not to let them watch it.
“I have never seen the video but what I have heard is very horrific.”
She added the charged officers had “disgraced their families”.
“I want to say to the five police officers who murdered my son, you also disgraced your own families when you did this.
“But I am going to pray for you and your families. Because this shouldn’t have happened. We want justice for my son.”
She has pleaded for peaceful protests.
Police pulled Mr Nichols over for alleged reckless driving before there was an “altercation” where officers used pepper spray on him, according to Shelby County district attorney Steve Mulroy.
Mr Nichols then tried to flee on foot and another altercation followed, he added.
His family say the officers beat him and the injuries he sustained during the encounter led to his death.
Relatives accuse police of causing him to have a heart attack and kidney failure. Authorities have only said he experienced a medical emergency.
The officers were assigned to the ‘scorpion’ unit which focuses on violent street crime. The family’s lawyers want it to be disbanded.
Memphis police chief Cerelyn Davis has said the department will review scorpion and other specialised units.
President Joe Biden said the Nichols family and the city of Memphis deserve “a swift, full and transparent investigation”.
“Public trust is the foundation of public safety, and there are still too many places in America today where the bonds of trust are frayed or broken,” he added.
Donald Trump says a meeting is being set up between himself and Vladimir Putin – and that he and Barack Obama “probably” like each other.
Republican US president-elect Mr Trump spoke to reporters at his Mar-a-Lago resort in Florida on Thursday, saying Russian president Mr Putin “wants to meet, and we are setting it up”.
“He has said that even publicly and we have to get that war over with. That’s a bloody mess,” Mr Trump said.
Kremlin spokesperson Dmitry Peskov said on Friday there was a “mutual desire” to set up a meeting – but added no details had been confirmed yet and that there may be progress once Mr Trump is inaugurated on 20 January.
“Moscow has repeatedly declared its openness to contacts with international leaders, including the US president, including Donald Trump,” Mr Peskov added.
“What is required is a mutual desire and political will to conduct dialogue and resolve existing problems through dialogue. We see that Mr Trump also declares his readiness to resolve problems through dialogue. We welcome this. There are still no specifics, we proceed from the mutual readiness for the meeting.”
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Trump on Obama: ‘We just got along’
Mr Trump also made some lighter remarks regarding a viral exchange between himself and former Democrat President Barack Obamaat Jimmy Carter’s funeral on Thursday.
The pairsat together for the late president’s service in Washington DC on Thursday, and could be seen speaking for several minutes as the remaining mourners filed in before it began.
Mr Obama was seen nodding as his successor spoke before breaking into a grin.
Asked about the exchange, Mr Trump said: “I didn’t realise how friendly it looked.
“I said, ‘boy, they look like two people that like each other’. And we probably do.
“We have a little different philosophies, right? But we probably do. I don’t know. We just got along. But I got along with just about everybody.”
The amicable exchange comes after years of criticising each other in the public eye; it was Mr Trump who spread the so-called “birther” conspiracy theory about Mr Obama in 2011, falsely asserting that he was not born in the United States.
Mr Trump has repeatedly attacked the Obamas, saying the former president was “ineffective” and “terrible” and calling former first lady Michelle Obama “nasty” as recently as October last year.
On Kamala Harris’s campaign trail last year, Mr Obama said Mr Trump was a “78-year-old billionaire who has not stopped whining about his problems since he rode down his golden escalator nine years ago”, while the former first lady said that “the consequences of him ever being president again are brutally serious.”
The US Supreme Court has rejected a last-ditch attempt by Donald Trump to delay sentencing in the Stormy Daniels hush money case.
The president-elect was convicted on 34 counts last May in New York of falsifying business records relating to payments made to Ms Daniels before the 2016 presidential election.
Prosecutors claimed he had paid her $130,000 (£105,300) in hush money to not reveal details of what Ms Daniels said was a sexual relationship in 2006.
Mr Trump has denied any liaison with Ms Daniels or any wrongdoing.
By a majority, the Supreme Court found his sentencing would not be an insurmountable burden during the presidential transition since the presiding judge, Juan M Merchan, has indicated he will not give Mr Trump jail time, fines or probation.
Mr Trump’s attorneys argued that evidence used in the Manhattan trial violated last summer’s Supreme Court ruling giving Mr Trump broad immunity from prosecution over acts he took as president.
At the least, they said, the sentencing should be delayed while their appeals play out to avoid distracting Mr Trump during the presidential transition.
Mr Trump’s attorneys went to the justices after New York courts refused to postpone sentencing.
Judges in New York found that the convictions related to personal matters rather than Mr Trump’s official acts as president.
Mr Trump’s attorneys called the case politically motivated, and they said sentencing him now would be a “grave injustice” that threatens to disrupt the presidential transition as the Republican prepares to return to the White House.
Mr Trump has said he will appeal again: “I respect the court’s opinion – I think it was actually a very good opinion for us because you saw what they said, but they invited the appeal and the appeal is on the bigger issue. So, we’ll see how it works out,” he said at a dinner with Republican governors at his private club in Florida.
Because the New York case was a state, rather than federal crime, Mr Trump will not be able to pardon himself when he takes office on 20 January.