A map of the 3,016 neurons that make up a baby fruit fly’s brain is the first of its kind, according to a new study.
Researchers say the map of the insect’s brain is the largest ever completed and shows every neuron – or messenger cell – in the organ and how they are wired together.
Experts say it could bring them closer to understanding the mechanism of thought and behaviour and has been described as a “big step forward”.
The project was led by Professor Marta Zlatic and Professor Albert Cardona, of the Medical Research Council Laboratory of Molecular Biology, which is based at the University of Cambridge.
“The way the brain circuit is structured influences the computations the brain can do,” said Professor Zlatic. “But, up until this point, we’ve not seen the structure of any brain except of the roundworm C. elegans, the tadpole of a low chordate, and the larva of a marine annelid, all of which have several hundred neurons.
“This means neuroscience has been mostly operating without circuit maps.
“Without knowing the structure of a brain, we’re guessing on the way computations are implemented.
“But now, we can start gaining a mechanistic understanding of how the brain works.”
The work took researchers 12 years to complete, with the imaging alone taking about a day per neuron.
Advertisement
The research, which has been published in the Science journal, was a joint project with experts at the University of Cambridge and Johns Hopkins University in the US, combining to complete the largest ever described brain connectome – a detailed map of neural connections in the brain.
In order to build an image of the fruit fly’s neural connections, the researchers had to scan thousands of slices of the larva’s brain before painstakingly reconstructing them to complete the map.
Then they could begin to meticulously annotate the connections between neurons on to the reconstructed image.
“This is a big step forward in addressing key questions about how the brain works,” said Jo Latimer, head of neurosciences and mental health at the Medical Research Council.
Current technology is not advanced enough to map the connectome for more complex animals such as large mammals, but this breakthrough could start to change that.
As well as mapping the 3,016 neurons, researchers mapped an incredible 548,000 synapses – the points of contact between neurons where information is passed between them.
“Super high-IQ revolutionaries” who are willing to work 80+ hours a week are being urged to join Elon Musk’s new cost-cutting department in Donald Trump’s incoming US government.
The X and Tesla owner will co-lead the Department Of Government Efficiency (DOGE) with former Republican presidential candidate Vivek Ramaswamy.
In a reply to an interested party, Mr Musk suggested the lucky applicants would be working for free.
Advertisement
“Indeed, this will be tedious work, make lost of enemies & compensation is zero,” the world’s richest man wrote.
“What a great deal!”
When announcing the new department, President-elect Donald Trump said Mr Musk and Mr Ramaswamy “will pave the way for my administration to dismantle government bureaucracy, slash excess regulations, cut wasteful expenditures, and restructure federal agencies”.
Mr Musk has previously made clear his desire to see cuts to “government waste” and in a post on his X platform suggested he could axe as many as three-quarters of the more than 400 federal departments in the US, writing: “99 is enough.”
At least 10 people have been killed after a fire broke out at a retirement home in northern Spain in the early hours of this morning, officials have said.
A further two people were seriously injured in the blaze at the residence in the town of Villafranca de Ebro in Zaragoza, according to the Spanish news website Diario Sur.
They remain in a critical condition, while several others received treatment for smoke inhalation.
Firefighters were alerted to the blaze at the residence – the Jardines de Villafranca – at 5am (4am UK time) on Friday.
Those who were killed in the fire died from smoke inhalation, Spanish newspaper Heraldo reported.
At least 10 people have been killed after a fire broke out at a retirement home in northern Spain in the early hours of this morning, officials have said.
A further two people were seriously injured in the blaze at the residence in the town of Villafranca de Ebro in Zaragoza, according to the Spanish news website Diario Sur.
They remain in a critical condition, while several others received treatment for smoke inhalation.
Firefighters were alerted to the blaze at the residence – the Jardines de Villafranca – at 5am (4am UK time) on Friday.
Those who were killed in the fire died from smoke inhalation, Spanish newspaper Heraldo reported.