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Some cough, cold and flu medicines are being withdrawn from pharmacy shelves as a precaution following concerns over very rare cases of allergic reaction.

Following a review by the Medicines and Healthcare products Regulatory Agency (MHRA), all medicines containing pholcodine are being withdrawn from the UK as a precaution.

Products from brands including Boots and Superdrug, as well as Day and Night Nurse, that are usually sold behind the counter among the 20 medicines being withdrawn.

Experts cited a “very rare” chance of people experiencing an allergic reaction when combined with general anaesthetic.

Pholcodine is used as a cough suppressant.

The medicines being recalled include:

• Boots Night Cough Relief Oral Solution

• Boots Dry Cough Syrup 6 Years+

• Boots Day Cold & Flu Relief Oral Solution

• Cofsed Linctus

• Care Pholcodine 5mg/5ml Oral Solution Sugar Free

• Galenphol Linctus

• Galenphol Paediatric Linctus

• Galenphol Strong Linctus

• Covonia Dry Cough Sugar Free Formula

• Pholcodine Linctus Bells Healthcare 5mg Per 5ml Oral Solution

• Numark Pholcodine 5mg per 5ml Oral Solution

• Well Pharmaceuticals Pholcodine 5mg per 5ml Oral Solution

• Superdrug Pholcodine Linctus BP

• Strong Pholcodine Linctus BP

• Pholcodine Linctus BP

• Strong Pholcodine Linctus BP

• Pholcodine Linctus

• Day & Night Nurse Capsules

• Day Nurse Capsules

• Day Nurse

Health experts say people should check the packaging of cough syrups or cough tablets they are taking to see if pholcodine is a listed ingredient and if so, talk to a pharmacist about alternatives.

Risk to patients who used pholcodine is ‘very small’

Professor Claire Anderson, president of the Royal Pharmaceutical Society, said: “All products containing the cough suppressant pholcodine have been withdrawn due to concerns of its potential to cause a severe allergic reaction in some people having general anaesthesia for surgery.

“The risk to patients who have used pholcodine is very small. If you are due to have surgery, please speak to your pharmacist or medical team for advice.

“This withdrawal is needed as safety of patients is paramount and we support efforts to ensure that all medicines on the market are safe and effective.”

She added that coughs usually clear up within three to four weeks and can be treated with other cough medicines, hot lemon and honey (not suitable for babies under one).

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The MHRA said that based on advice from the Commission on Human Medicines (CHM), the advisory body that provides expert advice on drug safety, it was recalling the products “as a precaution”.

It said that post-marketing safety data identified evidence that people who had taken the cough medicines were at an increased risk of a severe allergic reaction (anaphylaxis) when given general anaesthesia with neuromuscular blocking agents (NMBA).

Pholcodine-containing medicines are ‘pharmacy-only medicines’

Healthcare professionals have been advised by the MHRA to stop supplying the above products listed above “immediately” and “quarantine all remaining stock”.

The MHRA said that all pholcodine-containing medicines are “pharmacy-only medicines” which means they will have only been sold or dispensed under the supervision of a suitably trained healthcare professional.

In the UK recall notice, the MHRA said: “The available data has demonstrated that pholcodine use, particularly in the 12 months before general anaesthesia with NMBAs, is a risk factor for developing an anaphylactic reaction to NMBAs.”

It added: “Given the advice of the CHM and the lack of identifiable effective measures to minimise the increased risk of anaphylactic reactions to NMBAs, pholcodine-containing medicines are being withdrawn from the UK market and will therefore no longer be available in pharmacies.”

Healthcare workers have also been advised to check whether patients who are scheduled to undergo general anaesthesia with NMBAs have used pholcodine in the previous 12 months.

Europe’s medicines regulator, the European Medicines Agency, recommended the withdrawal of pholcodine medicines from the European market in December last year.

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Mosquito bite warning after rise in chikungunya cases in travellers returning to UK

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Mosquito bite warning after rise in chikungunya cases in travellers returning to UK

Travellers are being warned about mosquito bites on holiday after a rise in chikungunya infections in people returning to the UK.

The UK Health Security Agency (UKHSA) also said the first cases of the emerging oropouche virus had been recorded.

Chikungunya typically causes sudden fever and joint pain, which can be debilitating, and lasts from a few days to weeks.

The name comes from a word in a Tanzanian language meaning “that which bends up”, owing to the joint pain associated with it.

Most people recover but in some cases the symptoms can last several months or even years.

It’s spread by mosquito bites in tropical and subtropical regions, and most of the 73 cases reported in the UK so far this year were in London and linked to travel to Sri Lanka, India, and Mauritius.

Only 27 cases were reported in the same January to June period last year.

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Chikungunya can’t spread directly from person to person – so if someone becomes ill in the UK, they can’t pass the infection on, and the mosquitos responsible aren’t present here.

Dr Philip Veal, consultant in public health at the UKHSA, said it can be a “nasty disease” and the increase in cases was “worrying”.

“It is essential to take precautions against mosquito bites when travelling,” he said.

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“Simple steps, such as using insect repellent, covering up your skin and sleeping under insecticide-treated bed nets can greatly reduce the risk.”

Chikungunya is mainly found in Asia and Africa, but cases have been reported in Europe and North America this year.

Two vaccines to guard against the infection are available in the UK from private travel clinics.

The first cases of the Oropouche virus have also been confirmed in Britain, according to the UKHSA.

It’s spread by midge and mosquito bites and the three cases are all linked to travel to Brazil.

Oropouche was first identified in Trinidad and Tobago in the 1950s and had been mainly confined to the Amazon area.

However, cases have been increasing since 2023 and have shown up in places such as the Dominican Republic, Cuba, and Peru.

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Symptoms include fever, headache, muscle and joint pain, nausea and vomiting.

Anyone who gets such symptoms after being in Central and South America or the Caribbean is advised to get urgent medical advice.

Most people recover on their own, but it can cause severe disease in the very elderly or those with a weak immune system.

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Man staying at hotel that has been focus of protests denies sexual assault charge

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Man staying at hotel that has been focus of protests denies sexual assault charge

A man staying at a hotel that has been the focus of a series of protests has denied a charge of sexual assault and faces a trial next month.

Mohammed Sharwarq, a 32-year-old Syrian national, was arrested after police were called to the Bell Hotel on the Epping High Road in Essex yesterday, police said.

Sharwarq, who is alleged to have kissed a man on the neck, indicated a plea of not guilty to a charge of sexual assault at Chelmsford Magistrates’ Court today.

He indicated guilty pleas to six further charges concerning four complainants – with two counts of common assault and four of assault by beating.

Sharwarq is alleged to have punched a man in the face, thrown an object at a man, slapped a third man in the face and attempted to punch a fourth.

Sky News understands the alleged offences took place inside the hotel between 25 July and 12 August.

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District judge Lynette Woodrow remanded Sharwarq, who was assisted in court by an Arabic interpreter, in custody until his trial on 30 September.

The arrest followed weeks of protests outside the hotel.

Neil Hudson, the Conservative MP for Epping Forest, said last month that the protests were a crisis that “risks boiling over”.

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UEFA Super Cup: Spurs let slip 2-0 lead to lose to PSG on penalties

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UEFA Super Cup: Spurs let slip 2-0 lead to lose to PSG on penalties

Tottenham let slip a two-goal lead before losing a penalty shootout to Paris St Germain (PSG) in the final of the UEFA Super Cup.

Spurs defenders Micky van de Ven and Cristian Romero scored from set pieces to put the north London side on their way to winning the trophy, in what was manager Thomas Frank’s first game in charge.

However, Champions League winners PSG, who were thrashed in the Club World Cup final by Chelsea last month, produced a stunning response after Kang-in Lee pulled one back with five minutes left.

Tottenham's Cristian Romero scores his side's second goal. Pic: AP
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Tottenham’s Cristian Romero scores his side’s second goal. Pic: AP

PSG striker Goncalo Ramos, who was brought on in the 77th minute, forced the game to penalties after scoring a header in the fourth minute of stoppage time.

The Super Cup final, played each year between the winners of the Champions League and Europa League, does not feature extra time – meaning the game went straight to spot kicks.

Tottenham players react during the penalty shootout. Pic: AP
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Tottenham players react during the penalty shootout. Pic: AP

Europa League winners Tottenham initially had the advantage when Vitinha missed PSG’s first kick – but it was followed by Van de Ven and Mathys Tel failing to score their penalties.

PSG, managed by Luis Enrqiue, went on to win 4-3.

PSG's players celebrate after winning the final. Pic: AP
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PSG’s players celebrate after winning the final. Pic: AP

The PSG players poured on to the pitch in celebration, knowing they had etched their names into history as the first French side to lift the trophy.

“It’s incredible to win like this. This team once again showed character, even if we’re not at our physical best,” PSG defender Marquinhos said.

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PSG's Marquinhos lifts the trophy. Pic: AP
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PSG’s Marquinhos lifts the trophy. Pic: AP

“We managed to get the goals we needed through the substitutions, and in the shootout we have players who take their penalties well and a goalkeeper who helped us.”

Tottenham, who finished 17th in the Premier League last season, were unable to win what would have been their second trophy in 17 years – with the first one coming when they beat Manchester United in Europe’s second-tier competition in May.

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