Heavy Drinkers Still Can’t Hold Their Liquor

Published

2 years ago

June 23, 2023

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Share on Pinterest People who drink an excessive number of drinks will be impaired, even if they are heavy drinkers. Narcisa Palici / 500px/Getty ImagesA new study found that when people with alcohol-use disorder consumed the equivalent of seven to eight drinks they showed impairment on fine motor and cognitive tasks.This impairment was more than double what they experienced after consuming the smaller intoxicating amount of alcohol. Heavy drinkers and people with AUD both reported feeling less impaired than the light drinkers. Tolerance also does not reduce the damage that can be caused by alcohol, experts say.

While under some conditions, heavy drinkers may be better at holding their liquor, this is only true up to a certain level of alcohol intake, say researchers from the University of Chicago.

In a study published June 18 in Alcohol: Clinical and Experimental Research, they tested the effects of alcohol consumption on young adults with different patterns of alcohol use light and heavy social drinkers, and those with alcohol use disorder (or AUD, previously known as alcoholism). Differences between heavy and light drinkers

Researchers found that heavy drinkers and those with AUD showed less overall impairment on fine motor and cognitive tasks after consuming the equivalent of four to five drinks, compared to light drinkers.

This amount of alcohol is sufficient to produce a blood alcohol content (BAC) of 0.08-0.09%, the lower limit in the United States for drunk driving.

However, when people with AUD consumed the equivalent of seven to eight drinks which researchers say is more in line with their usual drinking habits, and produces a BAC of around 0.13% they showed impairment on both of those tasks.

In fact, this impairment was more than double what they experienced after consuming the smaller intoxicating amount of alcohol. Three hours after drinking, their performance on these tasks still hadnt returned to their baseline level.

In addition, people with AUD had greater impairment after consuming the larger amount of alcohol than what light drinkers experienced after drinking the lesser amount.

Theres a lot of thinking that when experienced drinkers (those with AUD) consume alcohol, they are tolerant to its impairing effects, study author Andrea King, PhD, a professor of psychiatry and behavioral neuroscience at the University of Chicago, said in a news release.

[Our study] supported that a bit, but with a lot of nuances, she added. When [young people with AUD] drank alcohol in our study at a dose similar to their usual drinking pattern, we saw significant impairments on both the fine motor and cognitive tests that was even more impairment than a light drinker gets at the intoxicating dose. Health effects of alcohol

Dr. Lawrence Weinstein, chief medical officer of American Addiction Centers, who was not involved in the new research, said the study highlights that technically, no one can handle their liquor.

There may be a marked difference in the amount of alcohol at which someone becomes intoxicated, which is a worrying issue in itself, but ethanol, acetaldehyde and other metabolites are toxicants that will affect anyone who consumes alcohol despite the tolerance theyve developed, he told Healthline.

Tolerance also does not reduce the damage that can be caused by alcohol, he said, adding: It is illogical to believe that one would remain unaffected by regular consumption [of alcohol].

According to the Centers for Disease Control and Prevention, more than 140,000 people die from excessive alcohol use in the United States each year, making it the fourth-leading preventable cause of death in the country.

In addition, almost 30% of U.S. traffic fatalities in 2019 involved alcohol-impaired driving, reports the National Highway Traffic Safety Administration.

Over the long term, excessive alcohol use can increase the risk of high blood pressure, heart disease, stroke, liver disease, certain types of cancer and other health problems.

[Alcohol is] costly to our society for so many reasons, said King in the release. Im hoping we can educate people who are experienced high-intensity drinkers who think that theyre holding their liquor or that theyre tolerant and wont experience accidents or injury from drinking. Different drinking patterns

In the new study, researchers enrolled almost 400 young people, most in their 20s, with different drinking patterns:light drinkers: consumed six or fewer drinks per week, with few binge drinking episodesheavy drinkers: consumed at least 10 drinks per week, with one to five heavy drinking episodes during that timedrinkers with AUD: consumed 28 or more drinks per week (21 or more for women), with at least 11 heavy drinking episodes per month; they also had to meet two or more clinical criteria for AUD

Binge drinking means consuming five or more drinks within about two hours for men, and four or more drinks for women.

Participants underwent two rounds of testing, one after consuming a high alcohol dose (the equivalent of four to five drinks) and the other after consuming a placebo drink containing only 1% alcohol (to create a similar taste). Both contained a flavored drink mix.

Researchers told participants they would receive a drink containing alcohol, a stimulant, a sedative or a placebo. This was to reduce the effect that peoples expectations might have on the results.

Participants consumed each drink over a 15-minute period.

Before drinking the beverage, and 30, 60, 120 and 180 minutes after drinking, participants took a breathalyzer and completed two performance tasks.

One task involved inserting a grooved metal peg into randomly slotted holes; this measured fine motor skills. The other was a pencil-and-paper task designed to test cognitive skills.

At the 30- and 180-minute intervals, participants also reported how impaired they felt. Impacts of higher alcohol intake

Heavy drinkers and people with AUD both reported feeling less impaired than the light drinkers.

In addition, these two groups showed less overall alcohol impairment on the fine motor and cognitive tests; although all groups had similar impairment on the fine motor test at the 30-minute interval.

The performance of heavy drinkers and people with AUD returned to baseline more quickly than that of light drinkers, suggesting they may have greater alcohol tolerance.

However, people with AUD often drink more than four or five drinks in a session. So researchers asked a subset of participants with AUD to repeat the tasks after consuming the equivalent of seven to eight drinks.

At this dose, they had more than double the impairment they experienced at the lower intoxicating dose. Their performance also did not return to baseline during the testing, even after three hours.

They also experienced greater impairment from that higher dose than light drinkers did after the lower intoxicating dose.

I was surprised at how much impairment that group had to that larger dose, because while its 50% more [alcohol] than the first dose, were seeing more than double the impairment, King said in the release.

Politics

President Bush determined to ‘rid world of evil-doer Saddam Hussein’, new records reveal

Published

2 hours ago

July 22, 2025

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President Bush determined to 'rid world of evil-doer Saddam Hussein', new records reveal

It would have been “politically impossible” to stop President Bush from invading Iraq, as he believed he was on a “crusade against evil”, new records show.

Newly declassified UK government files show Sir Tony Blair was warned by his US ambassador that George W Bush was determined to overthrow dictator Saddam Hussein, in the months before the invasion of Iraq.

Sir Tony, who was prime minister at the time, was trying to encourage the US president to use diplomatic means to change the situation in the Middle Eastern country, and flew to Camp David in January 2003 to make the case, just two months before the joint US-UK invasion.

The UK government was also hoping the United Nations Security Council would agree a new resolution specifically authorising the use of military force against Iraq.

But the files, made public for the first time, show that Sir Tony’s ambassador, Sir Christopher Meyer, warned him it would be “politically impossible” to sway Mr Bush away from an invasion unless Hussein surrendered.

The documents, released by the National Archives at Kew in west London, show Sir Christopher also wrote that Mr Bush believed himself to be on “a crusade against evil to be undertaken by God’s chosen people”.

Sir Tony’s foreign policy adviser, Sir David Manning, told the PM that when he met Mr Bush, he should make the point that a new diplomatic resolution was “politically essential for the UK, and almost certainly legally essential as well”.

But the White House was becoming increasingly impatient at the unwillingness of France and Russia – both of whom held a veto – to agree a resolution so long as UN inspectors were unable to find any evidence of Iraqi weapons of mass destruction, the supposed justification for war.

Sir Christopher warned Sir Tony shortly before his visit to see Mr Bush in January 2003 that options for a peaceful solution in Iraq had effectively run out.

He wrote: “It is politically impossible for Bush to back down from going to war in Iraq this spring, absent Saddam’s surrender or disappearance from the scene.

“If Bush had any room for manoeuvre beforehand this was closed off by his State of the Union speech.

“In the high-flown prose to which Bush is drawn on these set-piece occasions, he said in effect that destroying Saddam is a crusade against evil to be undertaken by God’s chosen people.”

In a cable sent the previous month, Sir Christopher said that much of the impulse for deposing Hussein was coming from the president, a born-again Christian, who was scornful of what he saw as the “self-serving” reservations of the Europeans.

“His view of the world is Manichean. He sees his mission as ridding it of evil-doers. He believes American values should be universal values,” Sir Christopher stated.

“He is strongly allergic to Europeans collectively. Anyone who has sat round a dinner table with low-church Southerners will find these sentiments instantly recognisable.”

In the end, Sir Tony and Mr Bush abandoned efforts to get a new Security Council resolution, blaming French President Jacques Chirac for refusing, and launched the invasion of Iraq anyway.

Lobbying from Mandelson and anger at the French

Among the new files, there are also a number of other revelations. These include:

Current UK ambassador to the US, Sir Peter Mandelson, was so desperate to get back into government following his second resignation from Sir Tony’s government that he asked Lord Birt, a policy adviser to Downing Street, to write to the prime minister in 2003, asking for him to receive a role – four months before Sir Peter was appointed as the UK’s next European commissioner
Sir Tony was furious at French president Jacques Chirac’s efforts to undermine pressure being put on Zimbabwean dictator Robert Mugabe by the UK in 2003, over growing violence caused by a policy of driving the remaining white farmers from their lands in the African nation
The prime minister also insisted on changing the rules around which parties can lay wreaths at the Cenotaph on Remembrance Sunday in a bid to protect the Northern Irish peace process in 2004, despite warning this could create an “adverse reaction” from the SNP and Plaid Cymru

Politics

People smugglers to have assets frozen and be banned from UK

Published

2 hours ago

July 22, 2025

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People smugglers to have assets frozen and be banned from UK

People smugglers face having their assets frozen and being banned from entering the UK, the foreign secretary has announced.

David Lammy said new powers under the Sanctions Act will allow the UK to freeze the assets of anyone complicit in smuggling illegal migrants into the country.

They can also be banned from travelling to the UK.

The first wave of sanctions on smuggling gangs and their enablers will be imposed on Wednesday.

Mr Lammy said it is the “world’s first sanctions regime” targeted at smuggling gangs.

Gang leaders, small boat suppliers, people making and selling fake passports and middlemen facilitating payments by migrants through hawala networks (informal systems for transferring money) will all be targeted this week.

They will be publicly named on a sanctions list, making it illegal for the UK financial system to engage with them.

By using the Sanctions Act, the government said it can target the smuggling gangs wherever they are in the world, including where law enforcement and criminal justice approaches cannot reach.

Labour’s manifesto promised to “smash the gangs”, but the first half of 2025 has seen a record number of small boat crossings, with about 20,000 from January to June – the highest ever in that period, and 48% more than the first half of 2024.

Earlier this month, the UK and France announced a pilot scheme under which migrants arriving in the UK illegally from France will be returned and a legitimate asylum seeker will be able to come to the UK. They did not say how many would be returned each week, but the suggestion was 50.

On the latest sanctions, Foreign Secretary David Lammy said: “For too long, criminal gangs have been lining their corrupt pockets and preying on the hopes of vulnerable people with impunity as they drive irregular migration to the UK. We will not accept this status quo.

“It is our moral duty and a key part of our Plan for Change to do all we can to smash these gangs and secure Britain’s borders.

“That’s why the UK has created the world’s first sanctions regime targeted at gangs involved in people smuggling and driving irregular migration, as well as their enablers.

“From tomorrow, those involved will face having their assets frozen, being shut off from the UK financial system and banned from travelling to the UK.”

Home Secretary Yvette Cooper said the sanctions send a “clear message that there is no hiding place for those who exploit vulnerable people and put lives at risk for profit”.

Environment

California set to BAN Tesla sales, Vietnam leads the way, and VW value tanks

Published

3 hours ago

July 21, 2025

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California set to BAN Tesla sales, Vietnam leads the way, and VW value tanks

The State of California is moving to ban the sale of Tesla cars amid claims that the company and its CEO, Elon Musk, have misled buyers about the self-driving capabilities of their cars. We’ve also got market-leading news out of Vietnam and a pricey, pricey lesson for one VW ID.Buzz buyer on today’s lesson-learning episode of Quick Charge!

We also ask what this might mean for the recent Uber/Lucid autonomous taxi tie-up and go through a full rundown of the fastest depreciating EVs on the market (and yes, there are four Tesla models in the top 10 … because the Cybertruck was too new to qualify).

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