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Source: Precision Neuroscience

It happened so fast that Craig Mermel missed it. 

He was standing in a busy operating room in West Virginia, waiting for a surgeon to place Precision Neuroscience’s neural implant system onto a conscious patient’s brain for the first time. Mermel, the president and chief product officer at Precision, said he looked away for a moment, and by the time he turned back, the company’s paper-thin electrode array was in position. 

In seconds, a real-time, high-resolution rendering of the patient’s brain activity washed over a screen. According to Precision, the system had provided the highest resolution picture of human thought ever recorded. 

“It was incredibly surreal,” Mermel said in an interview with CNBC. “The nature of the data and our ability to visualize that, you know, I got… chills.”

The procedure Mermel observed was the company’s first-ever in-human clinical study.

Founded in 2021 by a co-founder of Neuralink, Elon Musk’s brain-computer interface startup, Precision Neuroscience is an industry competitor working to help patients with paralysis operate digital devices by decoding their neural signals. A BCI is a system that deciphers brain signals and translates them into commands for external technologies, and several companies like Synchron, Paradromics and Blackrock Neurotech have also created devices with this capability. Precision announced a $41 million Series B funding round in January.

The company’s flagship BCI system, the Layer 7 Cortical Interface, is an electrode array resembling a piece of scotch tape. Since it’s thinner than a human hair, Precision says it can conform to the brain’s surface without damaging any tissue, and in the study, Precision’s system was temporarily placed onto the brains of three patients who were already undergoing neurosurgery to have tumors removed. 

Since the technology worked as expected, future studies will explore further applications in clinical and behavioral contexts, Mermel said. If the trials go according to Precision’s plan, patients with severe degenerative diseases like ALS could eventually regain some ability to communicate with loved ones by moving cursors, typing and even accessing social media with their minds.

Although an in-human study is a major milestone, the road to market for this type of technology is a long one. Precision has not yet received FDA approval for its device, and the company will have to work closely with regulators to successfully conduct several extremely thorough rounds of testing and data safety collection.

As of June, no BCI company has managed to clinch the FDA’s final seal of approval.

“The goal is to deliver a device that can help people living with permanent disability, so this is like the first step,” Mermel said. “Now the real work begins.”

Doctors prepare Precision’s system. Precision’s array compared to a penny.

Photo: Anna von Scheling

A number of different academic medical centers offered to support the company’s pilot clinical study, according to Dr. Benjamin Rapoport, co-founder and chief science officer at Precision. The company partnered with West Virginia University’s Rockefeller Neuroscience Institute, and the two organizations prepared for the procedures for more than a year in advance, Rapoport said.

Rapoport, who has been working on BCI technology for more than 20 years, said seeing Precision’s technology on the brain of a human patient for the first time was an “incredibly gratifying” milestone.

“I can’t really describe emotionally what that’s like,” he said. “It was tremendous.”

Dr. Peter Konrad, chairman of the Department of Neurosurgery at the Rockefeller Neuroscience Institute, was the surgeon who physically placed Precision’s system onto the patients’ brains during their procedures.

Konrad said it was a simple process that felt like laying a piece of tissue paper on the brain. 

Patients had Precision’s system on their brains for 15 minutes. One of them remained asleep during the procedure, but two patients were woken up so the Layer 7 could capture their brain activity as they spoke. 

“I’ve never seen that amount of data, 1,000 channels in real-time, of electrical activity, just washing over the brain as somebody was talking,” Konrad said in an interview with CNBC. “It was literally like you’re watching somebody think. It’s pretty amazing.”

Electrodes are already used in practice to help neurosurgeons monitor brain activity during a procedure, but the resolution provided by conventional systems is low. Konrad said standard electrodes are about four millimeters big, while Precision’s array can put 500 to 1,000 contacts on that size.   

“It’s the difference between looking at the world with an old black and white camera versus seeing in hi-def,” he said.

Konrad said it is too early for the patients in this study to see the direct benefits of this technology.

Precision’s array compared to a penny.

Photo: Anna von Scheling

Precision ultimately hopes its technology will not require open brain surgery at all. In an interview with CNBC in January, co-founder and CEO Michael Mager said a surgeon should be able to implant the array by making a thin slit in the skull and sliding in the device like a letter into a letter box. The slit would be less than a millimeter thick – so small that patients don’t need their hair shaved for the procedure. 

Precision’s minimally invasive approach is intentional, as competing BCI companies like Paradromics and Neuralink have designed systems meant to be inserted directly into the brain tissue. 

Rapoport said that inserting a BCI into the brain would provide a clear picture of what each neuron is doing, but it risks damaging the tissue and is difficult to scale. He said that level of detail is not necessary to decode speech or achieve the other functions Precision is striving for, so it was a tradeoff the company was ultimately willing to make.  

In the coming weeks, Precision will carry out the same procedure with two more patients as part of its pilot clinical study. Rapoport said the company has submitted its initial results to a scientific journal, and that having the data publicly available will be a “huge next step.”

Precision also has similar studies in the works with health systems like Mount Sinai in New York City and Massachusetts General Hospital in Boston, and Rapoport said Precision is hoping to receive full FDA clearance for its first-generation device next year. 

“The early results for us are tremendously gratifying to see,” Rapoport said. “If you’re lucky, there’s a few times in your life when you get to sort of see something before anybody else sees it in the world.”

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India is betting $18 billion to build a chip powerhouse. Here’s what it means

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India is betting  billion to build a chip powerhouse. Here’s what it means

A robotic machine manufactures a semiconductor chip at a stall to show investors during The Advantage Assam 2.0 Investment Summit in Guwahati, India, on Feb. 25, 2025.

Nurphoto | Nurphoto | Getty Images

India wants to become a global chip major, but the odds are steep: competition is fierce, and India is a late entrant in the race to make the most advanced chips.

In 2022, when the U.S. restricted exports of its advanced AI chips to China to curb Beijing’s access to cutting-edge technology, a global race for semiconductor self-reliance began.

For India, it offered an opportunity: the country wants to reduce dependence on imports, secure chips for strategic sectors, and capture a bigger share of the global electronics market shifting away from China.

India is one of the world’s largest consumers of electronics, but it has no local chip industry and plays a minimal role in the global supply chain. New Delhi’s “Semiconductor Mission” aims to change that.

The ambition is bold. It wants to create a full supply chain — from design to fabrication, testing and packaging — on Indian soil.

As of this month, the country has approved 10 semiconductor projects with total investment of 1.6 trillion rupees ($18.2 billion). These include two semiconductor fabrication plants, and multiple testing and packing factories.

India also has a pool of engineering talent that is already employed by global chip design companies.

Yet progress so far has been uneven, and neither the investments nor talent pool is enough to make India’s chip ambitions a reality, say experts.

“India needs more than a few fabs or ATP facilities (i.e., more than a few “shiny objects.”) It needs a dynamic and deep and long-term ecosystem,” said Stephen Ezell, vice president for global innovation policy at the Information Technology and Innovation Foundation, a science and technology policy think tank.

Ezell says that leading semiconductor manufacturers consider “as many as 500 discrete factors” before they set up multi-billion-dollar fab investments. These include talent, tax, trade, technology policies, labor rates and laws and customs policies — all areas where India has work to do.

New Delhi’s policy push

In May, the Indian government added a new element to its chip ambition: a scheme to support electronic component manufacturing, addressing a critical bottleneck.

Until now, chipmakers had no local demand for their product as there are hardly any electronic component manufacturing companies, such as phone camera companies, in India.

Researchers inside the semiconductor fabrication lab at the Centre for Nano Science and Engineering, at the Indian Institute of Science, in Bangalore.

Manjunath Kiran | Afp | Getty Images

But the new policy offers financial support to companies producing active and passive electronic components, creating a potential domestic buyer-supplier base that chip manufacturers can plug into.

In 2022, the country also pivoted from its strategy of providing superior incentives to fabrication units making chips of 28nm or less. When it comes to chips, the smaller the size, the higher the performance with improved energy efficiency. These chips can be used in new technologies like advanced AI and quantum computing by packing more transistors into the same space.

But this approach wasn’t helping India develop its nascent semiconductor industry, so New Delhi now covers 50% of the project costs of all fabrication units, regardless of chip size, and of chip testing and packing units.

Fab companies from Taiwan and the U.K., and semiconductor packaging companies from the U.S. and South Korea have all shown interest in aiding India’s semiconductor ambitions.

“The Indian government has doled out generous incentives to attract semiconductor manufacturers to India,” said Ezell, but he stressed that “those sorts of investments aren’t sustainable forever.”

The long road

The biggest chip project in India currently is the 910-billion-rupee ($11 billion) semiconductor fabrication plant being built in Prime Minister Narendra Modi’s home state of Gujarat by Tata Electronics, in partnership with Taiwan’s Powerchip Semiconductor Manufacturing Corp.

The unit will make chips for power management integrated circuits, display drivers, microcontrollers and high-performance computing logic, Tata Electronics said, which can be used in AI, automotive, computing and data storage industries.

The U.K.’s Clas-SiC Wafer Fab has also tied up with India’s SiCSem to set up the country’s first commercial compound fab in the eastern state of Odisha.

These compound semiconductors can be used in missiles, defence equipment, electric vehicles, consumer appliances and solar power inverters, according to a government press release.

“The coming 3-4 years is pivotal for advancing India’s semiconductor goals,” said Sujay Shetty, managing director of semiconductor at PwC India.

Establishing operational silicon fabrication facilities and overcoming technical and infrastructural hurdles that extend beyond incentives will be a key milestone, according to Shetty.

Opportunities beyond fab

NEW DELHI, INDIA – MAY 14: Union Minister of Railways, Information and Broadcasting, Electronics and Information Technology Ashwini Vaishnaw briefing the media on Cabinet decisions at National Media Centre on May 14, 2025 in New Delhi, India.

Hindustan Times | Hindustan Times | Getty Images

Last week, Indian minister Ashwini Vaishnaw, who was in Bengaluru to inaugurate a new office of semiconductor design firm ARM, said the British company will design the “most advanced chips used in AI servers, drones, mobile phone chips of 2 nm” from the south Indian city.

But experts say the role of local talent is likely to be limited to non-core design testing and validation, as the core intellectual property for chip designs is often held in locations like the U.S. or Singapore, where established IP regimes support such activities.

“India has sufficient talent in design space, because unlike semiconductor manufacturing and testing that has come up in the last 2 years, design has been there since 1990s,” said Jayanth BR, a recruiter with over 15 years of experience in hiring for global semiconductor companies in India.

He said global companies usually outsource “block-level” design validation work to India.

Going beyond this is something India’s government will need to solve if it wants to fulfil its semiconductor ambitions.

“India may consider updating its IP laws to address new forms of IP, like digital content and software. Of course, improving enforcement mechanisms will go a long way in protecting IP rights,” says Sajai Singh, a partner at Mumbai-based JSA Advocates & Solicitors.

“Our competition is with countries like the U.S., Europe, and Taiwan, which not only have strong IP laws, but also a more established ecosystem for chip design.”

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‘We need the smartest people’: Nvidia, OpenAI CEOs react to Trump’s H-1B visa fee

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'We need the smartest people': Nvidia, OpenAI CEOs react to Trump's H-1B visa fee

Nvidia CEO Jensen Huang attends the “Winning the AI Race” Summit in Washington D.C., U.S., July 23, 2025.

Kent Nishimura | Reuters

Nvidia CEO Jensen Huang and OpenAI CEO Sam Altman on Monday commented on President Donald Trump’s decision to increase the cost of hiring overseas workers on visas.

Trump on Friday announced that he would raise the fee for an H-1B visa to $100,000, leaving companies scrambling. Employers now must have documentation of the payment prior to filing an H-1B petition on behalf of a worker. Applicants will have their petitions restricted for 12 months until the payment is made, according to the White House.

Huang and Altman responded to the changes in an interview with CNBC’s Jon Fortt, where the two executives announced that Nvidia will invest $100 billion in OpenAI as the artificial intelligence lab sets out to build hundreds of billions of dollars-worth of data centers based around the chipmaker’s AI processors.

“We want all the brightest minds to come to the U.S. and remember immigration is the foundation of the American Dream,” Huang said Monday. “We represent the American Dream. And so I think immigration is really important to our company and is really important to our nation’s future, and I’m glad to see President Trump making the moves he’s making.”

OpenAI CEO Sam Altman also expressed a positive outlook on Trump’s changes.

“We need to get the smartest people in the country, and streamlining that process and also sort of outlining financial incentives seems good to me,” Altman said.

The new $100,000 fee would be a seismic shift for U.S. technology and finance sectors, which rely on the H-1B program for highly skilled immigrants, particularly from India and China. Those two countries accounted for 71% and 11.7% of visa holders last year, respectively.

Those who already have H-1B visas and are located outside the U.S. will not be required to pay the fee in order to re-enter. Many employers use H-1B workers to fill the gaps in these highly technical roles that are not found within the American labor supply. 

— CNBC tech reporter Annie Palmer contributed to this report.

WATCH: Watch CNBC’s full interview with Nvidia CEO Jensen Huang and OpenAI leaders Sam Altman and Greg Brockman

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Here’s everything Trump is changing with H-1B visas

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Here's everything Trump is changing with H-1B visas

President Donald Trump speaks before signing executive orders in the Oval Office at the White House on September 19, 2025 in Washington, DC.

Andrew Harnik | Getty Images

President Donald Trump raised the fee for an H-1B visa to $100,000 on Friday, leaving companies scrambling to respond.

With many left wondering whether their careers will remain in tact, here’s a breakdown of the new H-1B fees:

What did Trump change?

As of Sunday, H-1B visa applications will require a $100,000 payment. Previously, visa fees ranged from $2,000 to $5,000 per application, depending on the size of the company.

Employers now must have documentation of the payment prior to filing an H-1B petition on behalf of a worker. Applicants will have their petitions restricted for 12 months until the payment is made, according to the White House.

Who does this impact?

The fee will only be applied to new H-1B applicants, not renewals or current visa holders, according to White House press secretary Karoline Leavitt. The fee will be implemented in the upcoming lottery cycle.

Those who already have H-1B visas and are located outside the U.S. will not be required to pay the fee in order to re-enter.

Leavitt also clarified that the $100,000 is a one-time payment and not an annual charge.

Exceptions can be made to any immigrant whose employment is deemed essential in the national interest by the Secretary of Homeland Security and does not pose a threat to the security or welfare of the U.S.

Employees with B visas who have start dates prior to October 2026 will also receive additional guidance in order to prevent using those temporary business visas as a workaround for H-1B visas.

Who are these workers and why are they needed?

H-1B visas allows highly skilled foreign professionals to work in specialty occupations that generally require at least a bachelor’s degree to fulfill the role. Jobs in the fields of science, technology, engineering and math, or STEM, usually qualify.

Many employers use H-1B workers to fill the gaps in these highly technical roles that are not found within the American labor supply.

Companies in the tech and finance sectors rely heavily on these specially-skilled immigrants, particularly from India and China, which accounted for 71% and 11.7% of visa holders last year, respectively.

How many H-1B visas does the tech industry use every year?

The current annual cap for H-1B visas is 65,000, along with an additional 20,000 visas for foreign professionals with a master’s degree or doctorate from a U.S. institution. A lottery system is used to select additional petitions if demand exceeds the cap.

Since 2012, about 60% or more of approved H-1B workers had computer-related jobs, according to Pew Research.

Amazon was the top employer for H-1B holders in the fiscal year 2025, sponsoring over 10,000 applicants by the end of June, according to U.S. Citizenship and Immigration Services. Microsoft and Meta had over 5,000 each, while Apple and Google rounded out the top six with over 4,000 approvals.

WATCH: CoreWeave CEO on H-1B visas: Additional fee is ‘sand in the gears’ for access to talent

CoreWeave CEO on H-1B visas: Additional fee is 'sand in the gears' for access to talent

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