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Share on Pinterest Weight training can help build lean muscle. Getty ImagesNumerous factors are associated with increased or decreased Alzheimers disease risk.A new study indicates lean muscle mass may play a preventive role in disease onset. However, the reasons why muscle mass influences Alzheimers remain unclear.More research is needed to investigate the relationship and its mechanisms.

Experts have long recommended regular exercise as a potential approach to help reduce the risk of Alzheimers disease.

Now new research published in the British Medical Journal supports this thinking suggesting that developing lean muscle might offer a level of protection against the neurological condition.

University of California San Francisco scientists found that individuals with higher, lifelong levels of lean muscle mass had a 12% reduction in Alzheimers risk.

Previous studies have explored the role of obesity and body mass index (BMI) in Alzheimers development. However, these did not find evidence for a causal effect, said Dr. Iyas Daghlas, a third-year neurology resident at the University of California San Francisco and co-author of the study.

Uncertain whether BMI alone was a significant enough determinant of Alzheimers risk, the researchers wanted to explore body composition more closely.

[We] hypothesized that disaggregating body mass into lean mass and fat mass could reveal novel associations with disease, Daghlas told Healthline. What the study involved

The researchers used data from hundreds of thousands of individuals, the largest group of which came from the UK Biobank an ongoing database collecting half a million individuals health and genetic information.

Data was studied by employing Mendelian randomization, which uses gene variations as proxies for certain risk factors.

Further, bioimpedance measures an electrical current that runs through the body at various speeds depending on muscle and fat composition were used to estimate individuals lean muscle and fat mass.

A total of 584 genetic variants were linked to lean muscle mass, none of which were found in the area of the brain associated with vulnerability to Alzheimers.

On average, participants with greater levels of (genetically proxied) lean muscle had a statistically significant (12%) lower risk of developing the disease.

To affirm these findings, the researchers repeated the analytical process using data from a further 260,208 individuals, of which 7,329 had an Alzheimers diagnosis. Rather than in the legs and arms, they measured lean muscle mass in the trunk and whole body.

Again, they found that greater lean muscle was associated with reduced chances of developing Alzheimers.

One result was somewhat unexpected: while body fat was linked to poorer performance on cognitive tasks, once adjusted for lean mass, the analysis did not find a link between body fat and Alzheimers risk.

I was surprised by the striking discordance between the protective effect of lean mass on dementia risk and the absence of an effect of fat mass on dementia risk, stated Daghlas.What the findings didnt tell us

While the findings support a cause-and-effect association between muscle mass and Alzheimers risk, some unanswered questions remain.

For instance, it is unclear whether lean muscle has to be built before a certain age to positively influence Alzheimers development, or if it only impacts certain Alzheimers pathologies.

Further, this study does not directly address the question of whether factors behind the DNA such as proactively building muscle mass benefits from the association, said Dr. Anna Nordvig, a neurologist at NewYork-Presbyterian and Weill Cornell Medicine, who was not associated with the research.

Its also unknown whether those with mild signs of Alzheimers or cognitive impairment would experience symptom regression after building lean muscle.

That said, this study supports current recommendations to maintain a healthy lifestyle to prevent dementia, asserted Daghlas. It is a hopeful finding which gives patients agency in their neurologic health. How lean muscle and Alzheimers are related

Another limitation of the study is that the mechanisms behind the relationship between lean muscle and Alzheimers remain unclear.

The researchers briefly speculated on potential links. For instance, cardiovascular disease has long been affiliated with Alzheimers, although Daghlas noted the association is complicated.

Vascular dementia is driven by heart disease concerns such as stroke and hypertension, Daghlas said. In contrast, the most recent causal evidence suggests weaker evidence for an effect of vascular risk factors on Alzheimers disease risk, he explained though this is a controversial notion.

While further exploration is required, It may very well be the case that lean mass reduces the risk of vascular dementia via a reduction in cardiovascular disease risk, Daghlas said. This can be investigated in future studies.

The researchers also speculated in the paper that new mechanisms may be at play such as circulating centrally acting myokines.

Myokines are proteins released by muscles that affect other tissues, Daghlas revealed. They have been shown in experimental studies to be induced by exercise and to positively influence brain function.

Aside from these, other muscle-related factors may explain the larger picture, said Dr. Anna Nordvig, a neurologist at NewYork-Presbyterian and Weill Cornell Medicine, who was not associated with the research. For instance, bone hormones, cardio vs strength training differences, sex hormones, glymphatic drainage depending on exercise, and sleep, to name a few.

Ultimately, more clinical intervention studies are needed to confirm the effect of lean muscle on Alzheimers and the drivers behind the relationship. Steps to reduce your risk of Alzheimers

While theres no foolproof measure to prevent Alzheimers, experts believe various measures can aid in reducing your risk profile.

These fall into two categories, said Nordvig: protect and stimulate and physical activity falls into both of these.

Protect includes keeping an eye on things we discuss at a yearly physical, she explained such as blood pressure, sugar levels, weight, diet, and sleep.

There are environmental risk factors linked to Alzheimers that we should also aim to protect ourselves from, said Dr. Rena Sukhdeo Singh, a vascular neurologist with the University of Maryland Shore Regional Health.

Fine particulate matter in air pollution has also been linked to increased dementia risk.

Systemic inflammation is another factor associated with Alzheimers onset, Sukhdeo Singh said. Chronic inflammation can occur for many reasons, ranging from medications to high sugar and processed food intake to smoking and excessive alcohol consumption.

Meanwhile, stimulate involves optimizing other daily inputs that impact cognition. For instance, learning a new skill, hobby, language, or instrument, suggested Sukhdeo Singh, or engaging in shorter activities like sudokus, puzzles, and number games.

Unfortunately, were unable to influence some elements. Non-modifiable risk factors include age, genetics, and sex, she added.How to build lean muscle

Increasing your lean muscle mass is simpler than you might think, said Rachel Lovitt, certified personal trainer and founder of Mindful Movement and Living.

It involves challenging your muscles to do more than they normally do, recovering from that challenge, and providing your muscles proper fuel to both meet and recover from that challenge, she told Healthline.

Building lean muscle doesnt have to involve lifting heavy weights. Resistance training (or strength training) is any form of movement that uses resistance or external loads to challenge your muscle, Lovitt said.

Numerous weighted objects can be used, from dumbbells and kettlebells to resistance bands and water bottles. Even your own body weight can be enough, she added.

When it comes to moves, Lovitt recommended engaging in weighted actions that simultneously target multiple areas so you train your whole body.

For instance, squats are a great option for the lower body as they work so many muscle groups at once [and are] one of the most functional exercises out there, she stated. To target the upper body, moves to try include push-ups, shoulder presses, or rows.

The American College of Sports Medicine (ACSM) states you should strength train 2-3 times per week and increase your resistance by 2-10% once you can perform 1-2 repetitions past your goal, said Lovitt.

The ACSM recommends that novice, healthy resistance trainers do 1-3 sets per exercise, doing 8-12 reps, at 70-85% of one repetition max, she added.

But exercise is only one piece of the lean muscle picture.

Properly fueling your exercise is vital to increasing muscle mass, Lovitt stated. This means eating enough protein so your muscle has the building blocks to grow, she said, and ensuring your diet includes a good balance of micronutrients and macronutrients so your body can function properly.

Proper recovery is also essential. Muscles arent built in the gym, theyre built in your sleep, said Lovitt. Exercise is the stimulus that provokes muscle growth, but rest is when your muscles actually grow.

All of this can feel a little overwhelming, and exercises that work for one individual might not be so suited to another.

When it comes to increasing muscle mass, I highly recommend working with a qualified personal trainer or movement specialist so that you can come up with a plan that works for your unique life, body, and goals, Lovitt stated.

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Millions face council tax rise of more than 5% after government gives green light to bigger hikes

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Millions face council tax rise of more than 5% after government gives green light to bigger hikes

Millions of people face council tax hikes over normal thresholds after the government allowed six areas to boost rates above the usual 5%.

More than two million people will be hit by increases of between 5 and 10%.

Windsor and Maidenhead Council wanted to increase council tax by 25% but the plan was blocked – instead it will go up by 9%.

Newham Council will go up by the same amount, while Bradford Council will put up taxes by 10% and Birmingham, Somerset and Trafford councils will all put up rates by 7.5%.

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Speaking to Sky News’ Kay Burley, health and social care minister Karin Smyth defended the above normal increases – saying “many more councils” asked for permission to hike taxes, but were refused.

She said the ones given the nod “are particularly desperate” and need the money to keep “basic services running”.

The Labour MP was quick to blame the Conservatives, saying local government was left in a “really, really dark state” by the previous government.

How do councils increase tax?

In order to keep up with demands, councils are allowed to raise council tax usually by up to 5%, broken down into 3% core spending with an additional 2% for social care.

At the moment, a principle exists which prevents more than a 5% increase to council tax without a referendum, mostly to protect taxpayers from excessive increases.

But if a council is already in conversation with government on exceptional financial support, and if the government agrees to allow the council to raise tax above the cap as part of this, the council doesn’t necessarily have to take that to a local public vote.

Deputy prime minister Angela Rayner – who is also the secretary of state for local government – confirmed the move on Monday.

She said the average council tax increase across the country would not surpass last year’s total of 5.1%.

She also said more than £69bn in central funding would be made available to regional administrators, a rise of 6.8% compared to the 2024-25 period. Close to £4bn has also been put aside to help councils with social care.

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The Conservatives accused Labour of “pushing the burden on to taxpayers after they promised to freeze council tax”.

Shadow communities secretary Kevin Hollinrake said: “Their Local Government Finance Settlement will mean that councils will have to raise council tax to accommodate Labour’s jobs tax.

“This means that local people will pay more for less when it comes to local services, especially in rural areas which are losing the Rural Services Delivery Grant that Labour have abolished.

“The Labour Party have made false promises to local people, promising to freeze council tax while many councils will now have to raise it due to Labour’s political choice to raise council tax.”

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The County Councils Network, which represents 37 administrations, said they are facing pressure from the government’s decisions to increase national insurance contributions for employers, and increases to minimum wage.

Barry Lewis, the network’s finance spokesperson said: “More than four in five CCN members say they are in a worse position than before the autumn budget and this finance settlement, and one-third say their service reductions next year will now be severe.

“Considering there is very little fat left to cut from many of these services already, a further reduction will have a material impact on our residents.”

Ms Rayner confirmed allocations worth £502m to assist councils with the impact of increases to employer national insurance contributions.

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China hits back after new US tariffs take effect – as those against Mexico and Canada are paused

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China hits back after new US tariffs take effect - as those against Mexico and Canada are paused

China has retaliated after the US imposed 10% tariffs on its goods.

Not long after the US taxes began at 5am British time, China said it was imposing 10% tariffs on American crude oil, agricultural machinery, large-displacement cars and pickup trucks.

There will also be 15% tariffs on coal and liquefied natural gas, as well as an investigation into Google.

China also said it is imposing export controls on rare earth metals such as tungsten, tellurium, ruthenium, molybdenum and ruthenium-related items – the country controls much of the world’s supply of such metals, which are critical for the transition to clean energy.

They will not come into effect until Monday 10 February, however.

President Trump said his actions were in response to what he described as Beijing’s failure to stop the flow of fentanyl, a synthetic opioid, into the US.

Mr Trump added that the tariffs on China could just be the start, though the White House said he was due to talk to President Xi Jinping.

“China hopefully is going to stop sending us fentanyl, and if they’re not, the tariffs are going to go substantially higher,” Mr Trump said.

China has described fentanyl as America’s problem and said it would challenge the tariffs at the World Trade Organisation, as well as taking other countermeasures.

But it also left the door open for talks.

The issue of fentanyl is only one part of Mr Trump’s issue with China. He has long railed against the trade imbalance between the first and second-largest economies in the world.

Tariffs paused

Earlier, the imposition of 25% tariffs on Mexico and Canada was paused after agreements were reached on border security.

Mexico was first to make a deal with the White House. Its president, Claudia Sheinbaum, said she was sending 10,000 National Guard troops to the US border immediately in return for a tariff delay.

Mr Trump said the Mexican soldiers would be “specifically designated” to stop the flow of fentanyl into the US, as well as illegal migrants. Further negotiations will now be carried out, he added.

Ms Sheinbaum said she had a “good conversation” with him lasting at least 30 minutes just hours before the tariffs were due to begin.

She also extracted a concession from Mr Trump – after explaining the “seriousness” of high-powered weapons coming over the border from the US and getting into the hands of criminal groups.

“It gives them firepower,” she said. “We asked that the US also help our country by helping stop this arms trafficking… he agreed.”

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Canada made similar moves. Prime Minister Justin Trudeau said almost 10,000 frontline personnel “are and will be working on protecting the border”.

He added on X that his country was appointing a “fentanyl czar”, drug cartels would be listed as terrorists, and there would be “24/7 eyes on the border”.

There will also be a Canada-US joint strike force to “combat organised crime, fentanyl and money laundering”, Mr Trudeau announced.

Both Mr Trudeau and Mr Trump will view the deal as a win – Mr Trump for seemingly forcing the US’s northern neighbour to act, and Mr Trudeau for heading off sanctions with measures that for the most part (with the exception of the fentanyl czar) had already been announced in December.

Mr Trump said he was “very pleased with this initial outcome” and work will begin to see how a “Final Economic Deal” with Canada can be structured.

Tariffs are designed to show China’s mettle

Nicole Johnston

Asia correspondent

@nicole_reporter

China has made it clear it’s not taking Donald Trump’s 10% tariff lying down.

Despite the country still being on its New Year’s spring break, China has announced retaliatory measures.

Its tariffs of 10-15% hit exports of US coal, liquified natural gas (LNG), agricultural machinery and pick-up trucks to China.

However, these tariffs would not take effect until 10 February, giving Mr Trump and Chinese President Xi Jinping time to possibly hammer out a deal.

Canada and Mexico have been given a 30-day reprieve from the threatened 25% US tariffs.

China may be hoping it can also avert the start of a trade war by engaging in direct talks.

It’s believed Mr Trump and Mr Xi will speak on the phone in the coming days.

Chinese countermeasures extend beyond just tariffs though.

They have also restricted a handful of critical minerals like tungsten, launched an antitrust investigation into Google and sanctioned two US companies.

The Chinese government is strengthening its language against the US and its tariffs.

It is still open to negotiation in the spirit of the phase one US-China trade deal during Mr Trump’s first term, but it has a domestic audience to consider.

Beijing insists it is a peer competitor to the US and its rival on the world stage. These tariffs are designed to show China’s mettle.

What is the UK situation on tariffs?

President Trump hates trade deficits, and does not want to import more goods from another country than are sent there in return, says Sky’s economics and data editor, Ed Conway.

But Britain has bigger trade deficits than the US, Conway adds, and is one of the few countries in the world to import more goods from America than America imports from it.

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In addition, because the UK is no longer part of the European Union, any tariffs imposed on Brussels will not affect London.

When asked about the UK, Mr Trump said: “I think that one can be worked out.”

Sir Keir Starmer said it was “early days”.

Analysis: Has it all just been theatre?

First Mexico, now Canada. In another whirlwind day, both of America’s closest neighbours appear to have capitulated to President Trump.
The 25% tariffs on all goods from both countries were due to come into effect at midnight US Eastern time. But after calls between all three leaders, suddenly the tariffs were paused.

So what’s going on? Is this a clear signal of the power Trump wields? His blunt tool of using the threat of tariffs as a negotiating tool has paid off? Bullying tactics work? Well, maybe. At least that’s how Mr Trump wants everyone to think. Dance to my tune, or else.

And it’s absolutely the case that Mexico and Canada were in panic mode this weekend. But surely Donald Trump was panicking a little too when he saw the stock markets on Monday. He claimed this afternoon not to be taking any notice of their sharp falls. But we know he cares deeply about market reactions.

Here’s what’s interesting: the statement from Canadian Prime Minister Justin Trudeau sounded at first glance like it was announcing something new.
“Canada is implementing our $1.3bn border plan… nearly 10,000 frontline personnel are and will be working on protecting the border…”

But it’s not a new announcement. Look at the language – “are and will be”. In other words, “we’re doing this already Mr President, but if you want me to reiterate it to placate you, then I will…” All that Justin Trudeau has done today is reiterate a border plan he announced last December.

Mexico too has been doing an increasing amount in the fight against fentanyl though it could and probably now will do more.

So has it all been theatre this past 24 hours?

A show of brinkmanship from Donald Trump, which could have had a cliff-edge ending, but instead ended with him looking strong (and freaking out much of the developed world in the process) and his closest neighbours forced to reiterate their existing plans.

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Trump tariffs: How the UK finds itself in a strong position on US trade

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Trump tariffs: How the UK finds itself in a strong position on US trade

What if Britain has, almost entirely by accident, navigated itself into about the best possible position it could be in, as Donald Trump embarks on a trade war with nearly all his economic partners?

I realise this might, at first, sound a little odd. After all, when the world is facing economically-destructive measures (blanket tariffs are invariably value-destructive, in the short run at least) it’s hard to see much in the way of victories. Moreover, when it comes to Donald Trump, no one, including his own cabinet and staff, can quite predict what will happen next. Consider the roller-coaster over tariffs in the past few days alone.

Even so, the fact remains that of all the countries and regions in the world, Britain seems much less likely than most to face the kind of peremptory tariffs the president is so keen on.

Trade war latest: Trump pauses Mexico tariffs for a month

To see why, it helps to remember that the one thing Mr Trump hates above all else is trade deficits – when you import more goods (and it seems to be goods he mostly cares about) from another country than you send there in return.

America has an enormous trade deficit with China and with Mexico too, not to mention a smaller but not insubstantial deficit with Canada. When the president talks about the reasons for his tariffs he sometimes mentions illegal fentanyl imports, but, even more often, he references the size of the trade deficits. He wants America to make more stuff domestically and suck in less stuff from overseas.

We could have a long conversation (and I suspect we probably will have a long conversation in the coming months) about the extent to which deficits are, per se, a bad thing. But in the short run let’s focus on the UK and its strengths in this game.

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First, since the UK is no longer part of the European Union, it will not automatically face the same trade terms as its neighbours on the continent. If the US imposes tariffs on the EU, Britain will not necessarily face them.

Second, if there is one country in the world with even bigger trade deficits than the US, it’s Britain. This country has deindustrialised even quicker than America, with the upshot that unlike the EU or Canada or Mexico, Britain is one of the few countries in the world to import more goods from America than America imports from it.

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How will Trump’s tariffs affect Brits?

Footnote: that last point actually depends on whose numbers you’re looking at. Look at America’s figures and it has a trade surplus with the UK. Look at Britain’s figures and America has a trade deficit with us. But either way, both are very small. The numbers are essentially balanced.

Third, in recent months, the new Labour government has begun to improve its relationship with China. Chancellor Rachel Reeves went on a financial diplomacy mission to Beijing last month. And unlike nearly every other industrialised country in the developed world, Britain has not imposed tariffs on imports of Chinese electric vehicles.

Many diplomats have raised their eyebrows about this, but in the event that America wanted to do a deal with Britain, this is precisely the kind of thing the government could quickly reverse: “Oh alright then – in return for this trade deal, we’re willing to impose those tariffs on China – the ones everyone else has already introduced.”

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The funny thing about these three strengths is that, first off, up until recently many would have seen each of them – Brexit, our deindustrialisation and our cosying up to China – as weaknesses rather than strengths. They certainly weren’t part of any grand strategic plan.

Even so, the UK nonetheless finds itself in an unexpectedly propitious position when it comes to negotiating with the US. It has a better chance than most nations to act as a diplomatic bridge between America and Europe. Its chances of sealing that much-vaunted trade deal with the US have improved rather than deteriorated. Indeed, I’m told that leading members of the administration believe a trade deal with the UK could be sealed in a matter of months.

Whether that actually eventuates remains to be seen. After all, if there’s one thing you can’t predict when it comes to Donald Trump it’s, well, anything.

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