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UK scientists have begun developing vaccines as an insurance against a new pandemic caused by an unknown “Disease X”.

The work is being carried out at the government’s high-security Porton Down laboratory complex in Wiltshire by a team of more than 200 scientists.

They have drawn up a threat list of animal viruses that are capable of infecting humans and could in future spread rapidly around the world.

Which of them will break through and trigger the next pandemic is unknown, which is why it’s referred to only as “Disease X”.

Sky News was escorted around the site, which is run by the UK Health Security Agency, to see the work being done in high-containment labs.

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Risk of future pandemics ‘rising globally’

Professor Dame Jenny Harries, the head of the UK Health Security Agency (UKHSA), told Sky News: “What we’re trying to do here is ensure that we prepare so that if we have a new Disease X, a new pathogen, we have done as much of that work in advance as possible.

“Hopefully we can prevent it [a pandemic]. But if we can’t and we have to respond, then we have already started developing vaccines and therapeutics to crack it.”

The Vaccine Development and Evaluation Centre at Porton Down has been expanded to take on the work.

Originally, it was focused on COVID and testing the effectiveness of vaccines against new variants.

But scientists at the centre are now involved in monitoring several high-risk pathogens, including bird flu, monkeypox and hantavirus, a disease spread by rodents.

File photo dated 25/02/21 of the Dstl high containment lab building at Porton Down in Salisbury, Wiltshire
Image:
File photo of a high containment lab at Porton Down

One early success is the world’s first vaccine against Crimean-Congo haemorrhagic fever, a disease that’s spread by ticks and has a fatality rate of 30%.

Early-stage clinical trials have just started, with 24 volunteers expected to test the jab.

The disease is becoming more common in Europe as global temperatures rise and some travellers have returned to the UK with the infection.

Read more:
Deadly cat virus in Cyprus could be ‘potentially catastrophic for UK’
The NHS COVID app is closing down – but is the pandemic really over?

UK scientists have begun developing vaccines as an insurance against a new pandemic caused by an unknown ‘Disease X’. The work is being carried out at the government’s high-security Porton Down laboratory complex in Wiltshire by a team of more than 200 scientists.

Prof Harries said climate change and population shifts are making another pandemic more likely.

“What we’re seeing is a rising risk globally,” she said.

“Some of that is because of things like urbanisation where you may get virus jumping into humans [living close-by], as we’ve seen with bird flu.

“And some of it is because of climate change where you get things like ticks and mosquitoes moving to where it was previously cold and is now becoming increasingly warm.

“So this is a growing risk agenda. But it’s one we can use our science actively to prevent human impact.”

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Bird flu is currently thought to be the most likely pandemic threat.

The Royal Society for the Protection of Birds says at least 30,000 seabirds have died around the UK this summer as a more virulent strain of the H5N1 virus has swept around the world.

There is also evidence of limited spread in some mammals.

Bird flu is currently thought to be the most likely pandemic threat. The RSPB says at least 30,000 seabirds have died around the UK this summer as a more virulent strain of the H5N1 virus has swept around the world.
Image:
Bird flu is currently thought to be the most likely pandemic threat

And four people working on poultry farms in the UK have also tested positive, but were only mildly affected.

The UKHSA has started monitoring people in close contact with birds in case it can spread without causing symptoms.

The agency is part of a global effort to develop a vaccine within 100 days of a new pathogen being recognised as having pandemic potential.

“Historically, that would be unheard of,” said Prof Harries.

“It would normally take five or 10 years. For COVID it was around 360 days.

“So this is a really high ambition. But for some viruses, it is definitely possible.”

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America’s crypto renaissance is already failing; but we can fix it

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America’s crypto renaissance is already failing; but we can fix it

America’s crypto renaissance is already failing; but we can fix it

Opinion by: Shane Molidor, Founder, Forgd

For years, launching a crypto project in the United States has been a maze of uncertainty. Legal ambiguity and a hostile regulatory environment have driven founders offshore, turning places like Switzerland and the Cayman Islands into global hubs for blockchain innovation. 

With Trump’s election, things finally started to change, with a US administration openly declaring its intention to be crypto-friendly. Yet, despite the rhetoric, nothing concrete has changed so far.

Launching a crypto project in the US is just as difficult as ever. US regulatory agencies continue to offer nothing but vague threats and “regulation by enforcement” lawsuits. America wants to be a leader in crypto, but, even under the Trump administration, it isn’t taking action to create the conditions that would make that happen. 

Killing crypto in America

Every crypto project faces the same fundamental problem: Achieving decentralization is critical to avoid regulatory scrutiny, but until a project launches its token, a degree of centralization is unavoidable.

The SEC’s outdated Howey test ensures that nearly every legitimate crypto project gets classified as a security. The logic is self-defeating. Projects can’t decentralize without launching a token, but launching a token in the US instantly puts them in the SEC’s crosshairs.

This isn’t just a theoretical issue; it has real consequences. Liquidity providers, essential for all new token launches, won’t engage with US-based projects because they assume their tokens will be classified as securities. Centralized exchanges refuse to list tokens issued from US entities for the same reason. Even decentralized exchanges face pressure from their legal teams to avoid actively seeding liquidity for American projects. The result? US founders are boxed out of the global crypto economy before they even get started.

Offshore jurisdictions are winning

This regulatory failure has spawned an entire cottage industry of offshore legal firms specializing in setting up token-issuing entities. With its FINMA no-action letter system, Switzerland has become a hotbed for crypto projects because it offers one of the few structured ways to get legal clarity on a token’s classification. The Cayman Islands and British Virgin Islands have also established themselves as crypto safe havens, providing flexible corporate structures that allow projects to operate with far less regulatory risk. 

Recent: US Treasury wants to cut off Huione over ties to crypto crime

The absurdity is that the actual work — the development, the hiring, the innovation — still happens in the US. The token issuance gets pushed offshore via “Associations” and “Foundations,” which serve non-profits operating independently of US-based development shops. American founders are forced to funnel money into unnecessary legal fees, overseas operators, and shell foundations to avoid the inevitable crackdown from US regulators. This isn’t just bad for crypto; it’s bad for America. Until it can be solved, the US will continue to hemorrhage talent, investment, and influence to less myopic jurisdictions.

Make America crypto-friendly

The US has spent years fumbling crypto policy, and now, even with an administration that claims to be pro-crypto, it’s still failing to deliver real change. The solution isn’t to promise capital gains tax exemptions on crypto, as some have suggested. That does little to ameliorate the punishing regulatory landscape US-based projects are forced to navigate. If the US truly wants to lead in crypto, it also must take the lead in providing regulatory clarity.

That means finally recognizing that the same regulations that have governed traditional financial markets can’t always be applied to crypto. The Howey test doesn’t work. Instead, the government must provide a new and functional legal framework for the crypto industry. 

It’s time for US legislators and regulators to acknowledge that crypto tokens can’t achieve decentralization instantaneously and almost always require the efforts of a team of core contributors to bootstrap initial growth and development. The federal government must devise a version of the Howey test that does not automatically classify every new crypto token as a security but instead allows tokens a grace period to decentralize. In conjunction with this, the US must establish new protections to ensure insiders aren’t unduly benefiting from crypto projects while they scale. 

In addition to swiftly ending the “regulation by enforcement” approach employed under Gary Gensler’s SEC, a tactic seemingly designed to gradually smother crypto activity in the US, the government must provide clear guidelines. It needs to be feasible for market makers to evaluate whether US tokens are commodities or securities with a degree of stability and predictability. This is the only way to end the blanket bans market makers have placed on US tokens and bring crypto development back to America.

America’s window of opportunity is closing

Crypto founders aren’t waiting for Washington to figure it out. Every day, without clear regulations, more crypto projects are incorporated offshore. The US doesn’t even need to “embrace” crypto. It just needs to stop actively driving it away.

If this administration truly wants to make the US the leader in crypto, it needs to move beyond campaign slogans and start fixing the fundamental problems that forced this industry offshore in the first place. And it needs to act fast. 

Opinion by: Shane Molidor, Founder, Forgd.

This article is for general information purposes and is not intended to be and should not be taken as legal or investment advice. The views, thoughts, and opinions expressed here are the author’s alone and do not necessarily reflect or represent the views and opinions of Cointelegraph.

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Indonesia suspends WorldID over alleged registration violations

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Indonesia suspends WorldID over alleged registration violations

Indonesia suspends WorldID over alleged registration violations

OpenAI CEO Sam Altman’s digital identity project World, formerly Worldcoin, is facing challenges in Indonesia amid local regulators temporarily suspending its registration certificates.

The Indonesian Ministry of Communications and Digital (Komdigi) has halted the Electronic System Operator Certificate Registration (TDPSE) for World and World ID over suspicious activity and alleged registration violations, the authority announced on May 4.

After the suspension, Komdigi plans to summon World’s local subsidiaries, PT Terang Bulan Abadi and PT Sandina Abadi Nusantara, to provide clarification on the alleged violations, it said.

According to a preliminary investigation, World’s PT Terang Bulan Abadi was allegedly operating without TDPSE, while PT Sandina Abadi Nusantara — the one World was using for providing its services — is allegedly involved in legal misrepresentation.

Indonesian law requires registration by all digital service providers

In the statement, Komdigi emphasized that all digital service providers in Indonesia must receive electronic registration in accordance with local laws.

Additionally, using another entity’s registration is considered a major breach of Indonesian digital operations law, the authority noted.

“Worldcoin services are recorded using TDPSE in the name of another legal entity, namely PT Sandina Abadi Nusantara,” Alexander Sabar, the Komdigi’s director general for digital supervision, said in the announcement, adding:

“Noncompliance with registration obligations and the use of the identity of another legal entity to carry out digital services is a serious violation.”

Community action required

According to Sabar, World’s temporary suspension in Indonesia is a measure taken to prevent potential risks to the community.

He mentioned that the digital ministry is committed to overseeing the digital ecosystem fairly and strictly to ensure the security of the national digital space.

Indonesia suspends WorldID over alleged registration violations
Alexander Sabar is the head of Indonesia’s newly established Digital Space Monitoring Directorate General. Source: Komdigi

A proper supervision would require active participation from the community, Sabar added, stating:

“We invite the public to help maintain a safe and trusted digital space for all citizens. Komdigi also appeals to the public to remain vigilant against unauthorized digital services, and to immediately report suspected violations through the official public complaint channel.”

In the meantime, the community has apparently been divided over action by Komdigi.

“Good job Indonesia — at least somebody is standing up to that scam,” one commentator wrote on Reddit.

Related: From digital identity to outer space: Projects push crypto use cases

Others fired back, hinting at potential benefits stemming from World’s offering in Indonesia for the general public.

“If giving up your iris biometrics means you can feed your loved ones for a few weeks, that might be a trade worth making. In the end, it all depends on what matters most to you,” another Redditor said.

World’s latest news from Indonesia follows World’s debut in the United States in May 2025, with the platform rolling out its digital identity tech in six cities initially.

A number of global regulators were pushing back on World’s operations since its launch in July 2023, with governments like Germany, Kenya and Brazil expressing concerns over potential risks to the security of biometric data passed by users.

Magazine: Crypto wanted to overthrow banks, now it’s becoming them in stablecoin fight

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Donald Trump gives conflicting answers over memecoin profits

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Donald Trump gives conflicting answers over memecoin profits

Donald Trump gives conflicting answers over memecoin profits

US President Donald Trump gave clashing answers to whether he has profited from the crypto memecoin he launched in January, just days before he re-entered the White House.

In a wide-ranging interview with Kristen Welker on NBC News’ Meet the Press released on May 4, Trump said he was “not profiting from anything” when asked to respond to critics who said he’s profiting from the presidency through the memecoin.

“So you’re not profiting off of the cryptocurrency at all?” Welker asked Trump.

“I haven’t even looked,” Trump admitted.

“But I’ll tell you what. Look, if I own stock in something and I do a good job, and the stock market goes up, I guess I’m profiting.”

Trump launched his memecoin, Official Trump (TRUMP), on Jan. 17, which hit a peak of $73.43 two days later, just a day before he was inaugurated as president on Jan. 20, according to CoinGecko.

The token has been in a steady decline since launch, but it surged late last month after its website offered top holders a chance to dine with Trump on May 22. It’s currently trading at $11.35, down nearly 85% from its peak.

Trump was apparently unaware of his token’s recent surge, repeatedly asking how much it was now worth.  

Two companies, CIC Digital LLC, an affiliate of Trump’s sprawling Trump Organization, and Fight Fight Fight LLC, which is co-owned by CIC Digital, together own 80% of the token’s total 1 billion supply.

Most of those tokens are locked up and will be released over the next three years. The first unlock on April 18 saw 40 million tokens, worth $454 million, go to CIC Digital. 

Donald Trump gives conflicting answers over memecoin profits
Trump-controlled entities own 80% of the TRUMP token supply, which will be released periodically until 2028. Source: Trump Meme

Trump’s memecoin project has made at least $350 million so far, according to a March analysis from the Financial Times, which found those behind the token made $314 million from selling them and $36 million from fees.

Trump has been criticized over his many crypto dealings, which his opponents say are a conflict of interest as he looks to unburden the sector from regulators. 

Even those in his own party, Republican Senators Cynthia Lummis and Lisa Murkowski, have criticized Trump’s dinner offer to his top tokenholders. 

Trump said during the interview that he would contribute his presidential salary “back to the government,” prompting Welker to ask if he would also contribute any potential crypto earnings.

“I never thought of that,” Trump answered. “I mean, should I contribute all of my real estate that I’ve owned for many years if it goes up a little bit because I’m president and doing a good job? I don’t think so.”

Trump reiterates crypto commitment

In a part of the interview, Trump made a meandering statement that reiterated his campaign promise to support crypto.

“I want crypto. I think crypto’s important because if we don’t do it, China’s going to. And it’s new, it’s very popular, it’s very hot,” he said.

Trump claimed former President Joe Biden “went after it violently, and then, before the election, he changed his tune entirely” to garner the crypto vote. Biden did not run against Trump in the last election, instead handing the baton to then-Vice President Kamala Harris.

Related: Trump’s first 100 days ‘worst in history’ despite crypto promises 

The president again made his point when speaking to reporters on the White House South Lawn on May 4.

CBS News’ Jennifer Jacobs reported on X that Trump said “crypto is very important,” and wanted “to keep it away from China.”

He claimed China “will take it over, just like AI, just like so many other industries, or whatever you want to call them.”

Magazine: Trump’s crypto ventures raise conflict of interest, insider trading questions 

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