The second person to receive a heart transplanted from a pig has died, nearly six weeks after the highly experimental surgery.
Lawrence Faucette, 58, was dying from heart failure and ineligible for a traditional heart transplant when he received the genetically modified pig heart on 20 September.
The heart had seemed healthy for the first month, according to the University of Maryland School of Medicine, but started to show signs of rejection in recent days.
Mr Faucette’s wife, Ann, said her husband “knew his time with us was short and this was his last chance to do for others”.
“He never imagined he would survive as long as he did,” she added in a statement released by the hospital.
The world’s first pig heart transplant was carried out by the Maryland team in Baltimore last year.
David Bennett survived two months before that heart failed. Why it failed was not completely clear, but signs of a pig virus were found later inside the organ.
The transplant team made changes, including better virus testing, before the second experiment.
“Mr Faucette’s last wish was for us to make the most of what we have learned from our experience,” Dr Bartley Griffith, the surgeon who led the transplant, said in a statement.
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The team will analyse what happened with the heart as they continue studying pig organs, cardiac xenotransplant chief Dr Muhammad Mohiuddin added.
Attempts at animal-to-human organ transplants – called xenotransplants – have failed for decades, as people’s immune systems immediately destroyed the tissue that was not human.
Scientists are now trying to genetically modify pigs to make their organs more like those from humans.
Many scientists hope xenotransplants could one day compensate for the huge shortage of human organ donations.
There are about 7,000 people on the UK’s organ transplant waiting list.
Donald Trump has said he “hated” to see photos of Bill Clinton in the newly released Epstein files.
The former US president was in numerous images that were releasedby the US Department of Justice among thousands of documents related to the late paedophile financier Jeffrey Epstein.
In his first engagement in front of the media since the release of the latest files, Mr Trump was asked about the images of Mr Clinton.
“I think it’s terrible,” Mr Trump said, adding: “I like Bill Clinton… and I hate to see photos come out of him.
“I’ve always gotten along with Bill Clinton. I’ve been nice to him, he’s been nice to me. I hate to see photos come out of him, but this is what the Democrats, mostly Democrats and a couple of bad Republicans, are asking for.
“So they are giving photos of me to. Everybody was friendly with this guy [Epstein], either friendly or not friendly.
“He was all over Palm Beach and other places… and Bill Clinton was a friend of his, but everybody was.”
Image: Photos released of Bill Clinton included one showing him in a pool with Ghislaine Maxwell. Pics: US Department of Justice
He added: “Bill Clinton’s a big boy. He can handle it, but you probably have pictures being exposed of other people that innocently met Jeffrey Epstein years ago.”
The US president claimed the release of the files “is a way of trying to deflect from the tremendous success that the Republican Party has”.
Image: A painting of Bill Clinton in a dress was among the images released. Pic: US DoJ
Clinton calls for release of ‘any remaining materials’
In a statement on Monday, Angel Urena, a spokesman for Mr Clinton, called for Mr Trump to “release any remaining materials referring to mentioning or containing a photograph of Bill Clinton”.
The spokesman said the materials released so far “makes it clear someone or something is being protected” but said Mr Clinton doesn’t need such protection.
“Refusal to do so will confirm the widespread suspicion the Department of Justice’s actions to date are not about transparency, but about insinuation – using selective releases to imply wrongdoing about individuals who have already been repeatedly cleared by the very same Department of Justice, over many years under presidents and attorney generals of both parties,” the spokesperson added.
Trump on Venezuela, Epstein and Greenland: Key points
The context around the photos, that were released hours before a legal deadline in the US following the passing of the Epstein Files Transparency Act, is unknown.
The same release only features one picture with Mr Trump’s name in it.
Mr Clinton has denied any wrongdoing in connection to Epstein and says he regrets meeting him.
Backlash over release of files
It comes as other Democrats and Republicans have grown angry over the length of time it is taking the US Department of Justice to release all files in the Epstein case.
Several victims of Epstein told Sky News that the incomplete release left them feeling shocked, outraged and disappointed.
Epstein was ‘a monster’: Survivors speak to Sky News
Republican representative Thomas Massie and Democratic representative Ro Khanna said they are working together on an effort to secure the release of more files, and if necessary would seek contempt of Congress charges against Attorney General Pam Bondi.
Senate Democratic Leader Chuck Schumer also introduced legislation that would instruct Majority Leader John Thune, a Republican, to undertake “appropriate” legal steps to gain Congress access to all the documents covered by legislation that was passed by Congress and signed into law by Mr Trump.
It was not clear whether his effort might advance in the Senate when it returns on 5 January.
Donald Trump has announced a plan for the US Navy to build two new “Trump Class” battleships.
Aimed at cementing US naval dominance, the president said the vessels will be “the fastest, the biggest and 100 times more powerful than any battleship ever built”.
Constructed in America, made of steel and complete with missiles, guns, lasers and hypersonic weapons, the vessels will be the “centrepiece” of the US Navy’s Golden Fleet initiative, he said.
Starting with two vessels, Mr Trump said the project would eventually expand to include 20 to 25 new ships.
The first will be christened the USS Defiant, with the US leader personally involved in how it looks.
It comes as the US continues to build a large naval military presence near the coast of Venezuela. Since early September, it has struck more than 20 vessels in the Pacific Ocean and Caribbean Sea, which Mr Trump says is to crack down on drug cartels.
The US Navy has also seized two oil tankers and is believed to be in “active pursuit” of a third, according to officials.
Image: Donald Trump speaking about the Navy’s ‘Golden Fleet’. Pic: Reuters
“There’s never been anything like these ships. These have been under design consideration for a long time,” he said.
“Each one of these will be the largest battleship in the history of our country. The largest battleship in the history of the world.
“We haven’t built a battleship since 1994. These cutting-edge vessels will be some of the most lethal surface warfare ships… other than our submarines.”
Mr Trump made the announcement at his Mar-a-Lago estate in Florida. During the briefing, he stood next to mock-up pictures of the new vessels which had “Trump Class” written in the corner – what a senior administration official said the new class of vessel will be known as.
Image: Images of the new ‘Trump Class’ battleship. Pic: Reuters
In addition to the new battleship class, the project aims to increase the number of other types of war vessels, including a smaller, more nimble frigate class.
The term battleship has historically referred to a large, heavily armoured vessel armed with guns designed to bombard other ships or targets ashore.
This type of ship reached peak prominence during the Second World War. The largest of the US battleships was the Iowa-class.
Image: Pic: Reuters
The Trump administration has been complaining about the slow and expensive state of the current defence industry.
Just a month ago, the Navy scrapped its plans to build a new, small warship, citing growing delays and overrunning costs. It has also failed to build its other newly designed ships, like the new Ford-class aircraft carrier and Columbia-class submarines, on time and on budget.
Barry Manilow is being treated for lung cancer and has been forced to reschedule live shows, the 82 year-old has revealed.
The Copacabana popstar announced on Instagram that a cancerous spot had been discovered on his left lung.
“As many of you know I recently went through six weeks of bronchitis followed by a relapse of another five weeks,” he wrote.
“Even though I was over the bronchitis and back on stage at the Westgate Las Vegas, my wonderful doctor ordered an MRI just to make sure that everything was OK.
“The MRI discovered a cancerous spot on my left lung that needs to be removed.”
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Manilow, 82, added that the cancer had been found early thanks to “pure luck” and a “great doctor”.
And while he would not require chemotherapy or radiation treatment, he wrote, he would have to undergo surgery, forcing him to reschedule his January shows.
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He had been due to embark on a string of arena concerts in US cities including Orlando, Tampa, Charleston, Greensboro and Columbus.
He wrote: “I’m going into surgery to have the spot removed. The doctors do not believe it has spread and I’m taking tests to confirm their diagnosis.
“The only follow-up is a month to recover and that means we have to reschedule the January arena concerts.
“I’m very sorry that you have to change your plans.
“Just like you, we were all looking forward to the January shows and hate having to move everything around.”
Image: Barry Manilow poses for photographers ahead of a run of shows on Broadway in New York City in 2019. Pic: Reuters