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US regulators could approve the first new drug to treat Alzheimer’s in more than a decade, possibly paving the way for it to be used in the UK.

The Food and Drug Administration (FDA) is due to decide on Monday whether to approve Biogen’s aducanumab drug for use in the US.

Aducanumab targets amyloid – plaque that builds up in the brains of people with Alzheimer’s – helping to slow the onset of the condition.

It is the first treatment to target the cause of the disease, as existing ones only help to ease symptoms.

If approved, it could lead other pharmaceutical companies to create similar drugs and the UK regulator, the Medicines and Healthcare products Regulatory Agency (MHRA), to consider it for use in Britain.

Drugs company Biogen says that 1.5 million Americans would be eligible for the new drug, which is administered via infusion.

In the UK it could help the estimated 850,000 people living with the disease.

MPs have launched an investigation into the possible link between head injuries in sport and neurodegenerative diseases after campaigns by footballers and rugby players.

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Man who murdered four University of Idaho students in 2022 jailed for life

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Man who murdered four University of Idaho students in 2022 jailed for life

A man who murdered four University of Idaho students in November 2022 has been sentenced to life in prison – as the mother of one of his victims expressed her disappointment that he won’t be executed.

Bryan Kohberger, a 30-year-old former criminal justice student, initially denied the killings but later pleaded guilty as part of a deal that meant he would avoid the death penalty.

Kohberger sneaked into the rented home in Moscow, Idaho, which is not far from the university campus, through a kitchen sliding door and murdered Ethan Chapin, Xana Kernodle, Madison Mogen and Kaylee Goncalves.

Bryan Kohberger in court, and his victims Kaylee Goncalves, Maddie Mogen and Xana Kernodle, and Xana's boyfriend Ethan Chapin. Pic: AP
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Bryan Kohberger in court, and his victims Kaylee Goncalves, Maddie Mogen and Xana Kernodle, and Xana’s boyfriend Ethan Chapin. Pic: AP

Kohberger has never revealed his motive and it is not clear why he spared two roommates who were in the home.

Post-mortem examinations showed the four who died were stabbed multiple times and were likely asleep when they were attacked – with some sustaining defensive wounds.

Kohberger was arrested at his parents’ home in Pennsylvania weeks after the killings following a nationwide search.

Judge Steven Hippler sentenced Kohberger to four life sentences without parole for four counts of first-degree murder today.

Kaylee Goncalves (bottom left), Maddie Mogen (top left), Xana Kernodle and Xana's boyfriend Ethan Chapin
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Kaylee Goncalves (bottom left), Maddie Mogen (top left) and Xana Kernodle, and Xana’s boyfriend Ethan Chapin

A ‘delusional, pathetic, hypochondriac loser’

Family members of the victims gave statements in court today ahead of the sentencing – with the murderer’s mother Maryann Kohberger in attendance for the hearing.

Ms Kohberger quietly wept at times as the other parents described their grief.

Ms Goncalves’ mother Kristi Goncalves said she was disappointed that Kohberger won’t be executed by firing squad but revelled in how he would suffer in prison.

“You will always be remembered as a loser, an absolute failure,” she said.

“Hell will be waiting,” she added.

Kristi Goncalves at a hearing earlier this month. Pic: AP
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Kristi Goncalves at a hearing earlier this month. Pic: AP

Alivea Goncalves, the victim’s sister, drew applause after belittling Kohberger, who remained expressionless as she insulted him.

“You didn’t win, you just exposed yourself as the coward you are,” she said. “You’re a delusional, pathetic, hypochondriac loser.”

Steve Goncalves, the victim’s father, spoke to Kohberger directly and said: “Today we are here to finish what you started.”

Kohberger nodded subtly in response.

Alivea Goncalves speaks during the sentencing hearing. Pic: AP
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Alivea Goncalves speaks during the sentencing hearing. Pic: AP

Mr Goncalves added: “You tried to break our community apart, you tried to plant fear, you tried to divide us. You failed.”

In a statement read on her behalf by her lawyer, Ms Mogen’s mother Karen Laramie said: “Any one of us would have given our own life to have been outshone by hers.”

Ms Mogens’ mother declined to address Kohberger directly, as he remained expressionless, but closed her statement by saying the family might never forgive him or “ask for mercy” for what he did.

“His acts are too heinous,” her statement read.

Karen and Scott Laramie, the mother and stepfather of Madison Mogen, listen as their lawyer reads the statement. Pic: AP
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Karen and Scott Laramie, the mother and stepfather of Madison Mogen, outside court. Pic: AP

Bethany Funke, who survived the attack, said about her roommates in a statement to the court: “I hated and still hate that they are gone, but for some reason, I am still here and I got to live. I still think about this every day. Why me? Why did I get to live, and not them?”

She described one of the victims, Ms Kernodle, as “one in a million. She was the life of the party”.

Much of her statement was devoted to remembering her four close friends who died – recounting the nights they spent binge-watching reality television, making dinner together, going to parties at their university and the love that they had for each other.

Her testimony reduced many at the hearing to tears.

Bryan Kohberger. Pic: Reuters
Image:
Bryan Kohberger. Pic: Reuters

Dylan Mortensen, the second surviving roommate, said in court that she has panic attacks that force her to relive the trauma of what she experienced.

She said: “I was too terrified to close my eyes, terrified that if I blinked, someone might be there. I made escape plans everywhere I went… “He may have shattered parts of me but I’m still putting myself back together piece by piece,”

Kohberger’s head bobbed slightly as she spoke.

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‘Alligator Alcatraz’ detention centre compared to ‘dog cage’ with no distinction between night and day

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'Alligator Alcatraz' detention centre compared to 'dog cage' with no distinction between night and day

The already infamous ‘Alligator Alcatraz’ immigration detention centre in Florida has been compared to a “dog cage” amid concerns over conditions there.

Once destined to be the world’s largest airport, the facility has instead become a symbol of the White House’s determination to deport migrants from America which it says do not have a right to be in the country.

One detainee described feeling “in a state of torture” while a family member of another said “not even sunlight gets in”.

Supporters of President Donald Trump’s harsh stance on immigration have praised the new detention centre, in particular how natural obstacles in the surrounding Everglades such as alligators make escape difficult.

But for critics, it’s a dehumanising place that will cost hundreds of millions of dollars to run each year.

Rana Mourer waves an American flag outside of the migrant detention facility dubbed "Alligator Alcatraz," at the Dade-Collier Training and Transition facility, Saturday, July 12, 2025 in Ochopee, Fla. (AP Photo/Alexandra Rodriguez)
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Rana Mourer waves an American flag outside of Alligator Alcatraz. Pic: AP

Stories from inside Alligator Alcatraz

“It’s like a dog cage,” says detainee Rafael Collado, speaking to reporters on Tuesday over the phone from inside the facility.

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In the comments, reported by Sky News’ US sister outlet NBC News, he said that a combination of floodwater from recent storms, limited access to showers and poor sanitation have caused him to get fungus on his feet.

He said detainees are stripped naked every time they are moved to a different cell and there was not a set schedule for him to take his blood pressure medication.

At this point, he said he was being told by a guard to hang up and ended the call.

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US Representative says conditions in Alligator Alcatraz ‘really appalling’

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Meanwhile, Mexico is seeking the repatriation of 14 nationals that are being held at the centre.

Mexican father Martin Gonzalez told local radio station W that his sons, Carlos and Alejandro, were now held in the detention centre.

“It’s really bad. The facility is completely closed, not even sunlight gets in,” Mr Gonzalez said. “The lights are on 24-7, so they don’t even know if it’s day or night.”

Another detainee, Juan Palma, spoke to NBC Miami from inside Alligator Alcatraz on Monday.

“I feel like my life is in danger,” Mr Palma, who is Cuban, said.

He described feeling “in a state of torture,” being swarmed by mosquitoes during his sleep and unable to tell night from day because the facility’s fluorescent lights are always on.

An alligator swims in water at the entrance road of a temporary migrant detention centre, informally known as "Alligator Alcatraz",
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An alligator at the entrance road to the facility. Pic: AP

US government denies accusations

US Department of Homeland Security spokesperson, Tricia McLaughlin, denied all allegations of inhumane conditions at Alligator Alcatraz and at immigration detention centres across the nation.

She told NBC: “All detainees are provided with proper meals, medical treatment, and have opportunities to communicate with their family members and lawyers.

“Ensuring the safety, security, and well-being of individuals in our custody is a top priority.”

What is Alligator Alcatraz?

The Dade-Collier airport was once destined to be the world’s largest airport and would have been five times the size of New York City’s JFK, but it never fulfilled its potential.

Instead, the 39-square-mile facility located about 50 miles from Miami has been used as a training facility for years – until now.

“This is an old, virtually abandoned airport facility right in the middle of the Everglades,” Florida’s attorney general James Uthmeier said as he introduced it last month. “I call it: Alligator Alcatraz.”

He touted it as an “efficient, low-cost opportunity” to build a “temporary” detention centre “because you don’t need to invest that much in the perimeter”.

It’s believed that the facility could house 5,000 detainees when up and running and, according to CNN, will cost $450m (£328m) annually.

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US and Japan agree trade deal to circumvent worst of tariffs

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US and Japan agree trade deal to circumvent worst of tariffs

The US and Japan have agreed a trade deal days ahead of the latest tariff deadline set by Donald Trump.

Under the terms of the agreement, rather than all Japanese goods being hit with a 24% tax on entry to the US, they will instead be subject to a 15% tariff.

Significantly, and unlike the US-UK deal, there is no cap on the number of Japanese cars subject to the agreed lower tariff. The levy on cars and car parts has been brought down from 25% to 15%, making it the first country to secure a reduction in the blanket 25% rate on vehicles.

Cars make up more than a quarter of all Japan’s exports to the US.

Japanese steel and aluminium are still subject to a 25% tariff.

Money blog: Rival set to overtake Morrisons

It’s just over a week until the 1 August pause on tariffs is due to end, itself a six-week extension to the 9 July 90-day freeze US President Trump announced in April.

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It’s seen a win for all parties as Japan is a major trading partner of the world’s largest economy.

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What is in the UK-US trade deal?

To make the deal happen, Japan agreed to a $550bn (£406bn) investment package of loans and guarantees from Japanese government-affiliated institutions in key sectors like pharmaceuticals and semiconductors.

Japan will also increase purchases of US agricultural products such as rice.

Market reaction

Markets welcomed the news.

In the US, the value of a dollar ticked up, and in Japan, the benchmark stock exchange, the Nikkei, gained sizably, and closed up more than 3.5%.

The index is comprised of many major carmakers, including Nissan, Honda, Mazda, Toyota, and Mitsubishi, which all rallied following the news.

Other Asian stock indexes closed up, including Korea’s Kospi, which rose nearly 0.44%, Hong Kong’s Hang Seng, which increased more than 1.6%, and Thailand’s SET index, which was up more than 2.3%.

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