US regulators could approve the first new drug to treat Alzheimer’s in more than a decade, possibly paving the way for it to be used in the UK.
The Food and Drug Administration (FDA) is due to decide on Monday whether to approve Biogen’s aducanumab drug for use in the US.
Aducanumab targets amyloid – plaque that builds up in the brains of people with Alzheimer’s – helping to slow the onset of the condition.
It is the first treatment to target the cause of the disease, as existing ones only help to ease symptoms.
If approved, it could lead other pharmaceutical companies to create similar drugs and the UK regulator, the Medicines and Healthcare products Regulatory Agency (MHRA), to consider it for use in Britain.
Drugs company Biogen says that 1.5 million Americans would be eligible for the new drug, which is administered via infusion.
In the UK it could help the estimated 850,000 people living with the disease.
MPs have launched an investigation into the possible link between head injuries in sport and neurodegenerative diseases after campaigns by footballers and rugby players.
Joe Biden and Kevin McCarthy reach ‘agreement in principle’ on raising US debt ceiling
President Joe Biden and House Speaker Kevin McCarthy have reached an “agreement in principle” on raising the US debt ceiling, according to sources in Washington.
The tentative deal would bring to an end the months-long stalemate between the Republican controlled Congress and Democrat run White House.
Currently, the debt ceiling stands at $31.4trn (£25.4trn) with the new limit yet to be announced.
Mr Biden and Mr McCarthy held a 90-minute phone call on Saturday evening to discuss the deal, as the 5 June deadline looms.
Following the conversation, the speaker tweeted: “I just got off the phone with the president a bit ago.
“After he wasted time and refused to negotiate for months, we’ve come to an agreement in principle that is worthy of the American people.”
During a very brief press conference on Capitol Hill Mr McCarthy said they “still have more work to do tonight to finish the writing of it”, adding that he expects to finish writing the bill on Sunday, then hold a vote on Wednesday.
The deal would avert an economically destabilising default, so long as they succeed in passing it through the narrowly divided Congress before the Treasury Department runs short of money to cover all its obligations.
Republicans have pushed for steep cuts to spending and other conditions, including new work requirements on some benefit programmes for low-income Americans and for funds to be stripped from the Internal Revenue Service, the US tax agency.
They said they want to slow the growth of the US debt, which is now roughly equal to the annual output of the country’s economy.
Biden cancels visits to Australia and Papua New Guinea to deal with debt crisis
Could US default on its debt? UK should be praying it doesn’t
Exact details of the deal were not immediately available, but negotiators have agreed to cap non-defence discretionary spending at 2023 levels for two years, in exchange for a debt ceiling increase over a similar period, according to Reuters news agency.
The impasse frightened the financial markets, weighing on stocks and forcing the US to pay record-high interest rates in some bond sales.
A default would take a far heavier toll, economists say, likely pushing America into recession, rocking the world economy and cause unemployment to spike.
Winnie The Pooh characters used in US school district’s mass shootings safety book
A Dallas school district has apologised after distributing a Winnie The Pooh-themed book about school shootings.
The book is titled Stay Safe: Run, Hide, Fight and its cover says: “If there is danger, let Winnie the Pooh and his crew show you what to do.”
Inside, it includes passages such as: “If danger is near, do not fear. Hide like Pooh does until the police appear. Doors should be locked and the passage blocked. Turn off the light to stay out of sight.”
Dallas Independent School District said in a statement it works “hard every day to prevent school shootings” by dealing with online threats and improving security measures.
“Recently a booklet was sent home so parents could discuss with their children how to stay safe in such cases,” the statement read.
“Unfortunately, we did not provide parents [with] any guide or context. We apologise for the confusion and are thankful to parents who reached out to assist us in being better partners.”
The school district did not say how many pupils received the book.
California’s governor, Gavin Newsom, was among those who criticised the book, posting on Twitter: “Winnie the Pooh is now teaching Texas kids about active shooters because the elected officials do not have the courage to keep our kids safe and pass common sense gun safety laws.”
‘It’s not exactly cute’
Cindy Campos, whose five-year-old son was sent home with the book, said she cried when she read it.
“It’s hard because you’re reading them a bedtime story and basically now you have to explain in this cute way what the book is about, when it’s not exactly cute,” she said.
Ms Campos said it seemed especially “tone deaf” to send it home around the time Texas was marking the anniversary of last year’s mass shooting at a school in Uvalde, when a gunman killed 19 children and two teachers.
The book was published by Praetorian Consulting, a Houston-based firm that provides safety, security, and crisis management training and services.
The company says on its website that it uses age-appropriate material to teach the concepts of “run, hide, fight” – the approach US authorities say civilians should take in active shooter situations.
Read more: America’s 10 most deadly mass shootings of 2023
Active shooter drills have become common in American schools in recent years.
While many associate the characters of Winnie The Pooh with Disney, they are free to use legally in the US with no repercussions.
US copyright law means that works of authors are available to use by anyone either 70 years after the author’s death or 95 years after publication.
As well as the book, AA Milne’s characters have also been featured in a recent horror film titled Winnie The Pooh: Blood and Honey.
Boy, 11, ‘shot in the chest’ by police officer he had called for help
An 11-year-old boy who was shot by a police officer has returned home from hospital after almost a week of treatment.
Aderrien Murry spent five days in hospital with a collapsed lung, lacerated liver, and fractured ribs after the officer shot him in the chest early on Saturday, lawyer Carlos Moore said.
Aderrien was well enough to leave hospital on Wednesday, and is continuing his recovery at home in Indianola, about 95 miles northwest of Jackson, Mississippi.
Mr Moore said the family is “demanding justice”.
“An 11-year-old black boy in the city of Indianola came within an inch of losing his life – he had done nothing wrong and everything right.”
Mr Moore said that Aderrien’s mother Nakala had asked him to call police at about 4am on Saturday after a previous partner had showed up at home.
Ms Murry felt threatened, Mr Moore said, and the child had “called the police to come to his mother’s rescue, he called his grandmother to come to his mother’s rescue, the police came there and escalated the situation”.
Two police officers arrived and one kicked the front door before Ms Murry opened it, telling them that the man had gone but her three children were inside.
Child does not understand why a police officer shot him
Mr Moore said that Sergeant Greg Capers, who is black, yelled out that anyone inside should come out with their hands up.
When Aderrien walked into the living room with nothing in his hands, Capers shot him in the chest, Mr Moore said.
Indianola City Attorney Kimberly Merchant confirmed to Indianola’s Enterprise-Tocsin newspaper that Capers was the officer who shot the little boy and Mr Moore said on Thursday that Capers had been suspended with pay while the incident is investigated.
Ms Murry said her son is “blessed” to be alive but he does not understand why a police officer shot him.
Read more US news:
FBI says IRA planned to kill Queen
Mum ‘offered son help to dispose of body’
US Capitol rioter pictured with feet on Pelosi’s desk jailed
‘That’s my child, y’all’
She described what had happened as “the worst moment in my life”, adding: “I feel like nobody cares – that’s my child, y’all.”
Mississippi Bureau of Investigation said its agents are looking into what happened and will share their findings with the Attorney General’s Office.
Sports7 months ago
‘Storybook stuff’: Inside the night Bryce Harper sent the Phillies to the World Series
Technology2 years ago
Game consoles were once banned in China. Now Chinese developers want a slice of the $49 billion pie
Sports2 years ago
Team Europe easily wins 4th straight Laver Cup
Politics1 year ago
Have the last few wobbly weeks seen a turning point for Johnson as PM?
Business8 months ago
Bank of England’s extraordinary response to government policy is almost unthinkable | Ed Conway
Politics1 year ago
Yvette Cooper promoted and Lisa Nandy to shadow Gove on levelling up brief in Labour reshuffle
Business8 months ago
Liz Truss’s ‘favourite’ economist says chancellor ‘took his eye off ball’ and ‘overstepped the mark’ with mini-budget
Videos8 months ago
World leaders come together for Queen Elizabeth’s funeral