Vaccine manufacturers have expressed confidence that they will be able to rapidly adapt their jabs if the Omicron variant spreads.
The new strain – previously known as B.1.1.529 – features some “concerning” mutations, and early evidence suggests it brings an increased risk of reinfection.
There are also fears that the variant could be more resistant to the vaccines that have now been rolled out to billions of people around the world.
Image: Omicron’s spike protein with new mutations seen in red, blue, gold and black. Pic: Centre for Virus Research at the University of Glasgow
If this is the case, Pfizer and BioNTech expects “to be able to develop and produce a tailor-made vaccine against that variant in approximately 100 days, subject to regulatory approval”.
Moderna said it has advanced a “comprehensive strategy to anticipate new variants of concern” since early 2021 – including three levels of response if the immunity offered by its jabs wanes.
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Novavax added it has already started creating a COVID-19 vaccine based on the known genetic sequence of B.1.1.529 “and will have it ready to begin testing and manufacturing within the next few weeks”.
Yesterday, the World Health Organisation designated B.1.1.529 as a “variant of concern”, meaning it has now officially been given the name Omicron, a letter from the Greek alphabet.
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The strain was first detected in South Africa, and a number of countries – including the UK, Australia and the US – are now temporarily restricting travel to a number of European countries.
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Although no infections linked to the Omicron variant have been detected in the UK or the US so far, there has been a case in Belgium involving an unvaccinated person who had travelled abroad.
Salim Abdool Karim, one of South Africa’s top epidemiologists, told Sky News he “would expect it to be in the UK” by now.
Health Secretary Sajid Javid has warned that there is a “possibility it might have a different impact on individuals” who get coronavirus.
However, he stressed the UK remains in a “strong position” due to the high vaccination take-up – adding that Omicron’s presence means getting a booster jab is even more important now.
British scientists first became aware of the new strain on 23 November after samples were uploaded on to a COVID variant tracking website from South Africa, Hong Kong and then Botswana. A total of 59 samples have been uploaded so far.
Amid the concerns, flights to the UK from South Africa and five other southern African countries – Namibia, Lesotho, Botswana, Eswatini and Zimbabwe – have been suspended until 4am on Sunday.
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2:41
‘Huge international concern’ over variant
These nations have now been added to the red list, and from Sunday, British nationals returning from these destinations will be required to quarantine in government-approved hotels for 10 days.
Mr Javid confirmed the government is still following Plan A for managing COVID-19 this autumn and winter but warned “if we need to go further, we will”.
England’s chief medical officer, Professor Chris Whitty, has said his “greatest worry” is whether the public would accept fresh restrictions if they were required.
Volodymyr Zelenskyy has called on Ukraine’s partners to make sure Russia doesn’t “deceive” them over a ceasefire.
After breakthrough talks between Ukrainian and US officials in Saudi Arabia, Kyiv said it was ready to accept a proposed 30-day ceasefire with Russia.
But his nightly address on Wednesday evening, a day after the Jeddah summit, President Zelenskyy said, “we must move toward peace” – but issued a warning to allies.
“The key factor is our partners’ ability to ensure Russia’s readiness not to deceive but to genuinely end the war,” the Ukrainian leader said. “Because right now, Russian strikes have not stopped.”
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The focus has now switched to Vladimir Putin’s response to the proposed ceasefire. President Trump said the US had received “some positive messages” adding: “We have people going to Russia right now”.
However, he warned Moscow: “In a financial sense, yeah we could do things very bad for Russia, would be devastating for Russia.”
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Will Russia go for ceasefire deal?
European defence ministers, meeting in Paris, said now was the time for Moscow to show it was serious about ending the war.
UK Defence Secretary John Healey was among those attending, and had a direct message for Russia’s president: “I say to president Putin, over to you, you want to talk, prove it.”
Mr Healey called on Russia to accept the ceasefire and end the war, adding, “the pressure is now on Putin”.
For his part, President Putin has been playing to his domestic audience with a visit to Kursk, where Russian troops finally seem to be gaining the upper hand against Ukrainian forces who seized territory in the Russian region last year.
Image: The Russian line is approaching Sumy from Kursk Oblast
Dressed in camouflage, the Russian president called for his forces to defeat the enemy and completely liberate Kursk, in remarks reported by the Interfax news agency.
He also said enemy troops captured in the region will be treated as terrorists, as Russia’s chief of the general staff told Mr Putin that Ukrainian forces in the region are surrounded.
Hostages have been killed after separatist militants hijacked a train carrying hundreds of passengers in Pakistan, authorities have said.
The Pakistan military (ISPR) said 21 hostages were killed, as well as four security force soldiers, on the train that was carrying more than 400 people.
Earlier on Wednesday, the Baloch Liberation Army (BLA) claimed responsibility for the attack and said they had killed 50 people.
A Pakistani government spokesman described the attack as “an act of terrorism,” and passengers who had been freed described how gunfire was “coming from everywhere”.
ISPR director general Ahmed Sharif Chaudhry added in a statement: “Today we freed a large number of people, including women and children. The final operation was carried out with great care.”
Image: A soldier stands guard next to a rescue train after the hijack by separatist militants. Pic: Reuters
The train was hijacked on Tuesday as it entered a tunnel in Bolan, a district in the southwestern province of Balochistan.
The Jaffar Express was packed with 440 people, including women and children, Mr Chaudhry told local broadcaster Dunya TV.
He added that “militants were in touch with their handlers and masterminds in Afghanistan via satellite phones” during the incident.
Image: Passengers rescued by security forces from the hijacked train. Pic: AP
The train was on a 1,000-mile journey from Quetta to the city of Peshawar.
Militants blew up the railway tracks before firing at the train, killing the driver and trapping it inside a tunnel at Mashkaf.
Security forces exchanged gunfire with the militants who were wearing vests loaded with explosives.
Image: The train was hijacked as it entered a tunnel in Bolan, Pakistan
‘God saved us’
Noor Muhammad, who was travelling with his wife, said: “First, they hit the engine with an RPG (rocket-propelled grenade).
“After that, gunfire started and explosions were heard, RPGs were used. God saved us.
“They made us get off (the train) and told us to get down or they would shoot. We got down and then they said ‘leave’.”
Image: Officials said a large number of the hostages had been rescued. Pic: AP
Bashir Yousaf, who was with his family, said: “Everyone was crying and passengers were shouting, everyone was lying on the floor trying to save their lives.
“The sound of gunfire was coming from everywhere, then they (insurgents) told us to get down.
“After getting off we were told not to look back. I just kept walking without looking back to save my family’s lives.”
Image: A soldier keeps watch near to the scene of the hijacked train. Pic: AP
Mr Chaudhry added to Dunya TV that security forces “first took out some of the militants and then began clearing compartment by compartment killing the militants”.
He said the total number of militants was 33, and added that no passenger was hurt or killed during rescue operations.
However, he added that before “the final clearance,” 21 people were killed by the militants. Four Frontier Corps soldiers were also killed.
“Perpetrators will be hunted down and will be brought to justice,” he said. “This incident of the Jaffar Express changes the rules of the game.”
Image: Soldiers and police have been deployed at sites close to the hijacking. Pic AP
Earlier in the day, Pakistan’s Prime Minister Shehbaz Sharif condemned the attack and said security officials were “repelling” the militants, while interior minister Mohsin Naqvi called the attackers “enemies” of the country.
The BLA – designated a terrorist organisation by the UK – had demanded the release of Baloch political prisoners, activists, and missing persons within 48 hours.
It had threatened to start executing the hostages if the government did not fulfil its demands.
The group often targets infrastructure and security forces in Balochistan but has also struck in other areas, including the southern port city Karachi and the strategic port of Gwadar on the Arabian Sea.
Hostages have been killed after separatist militants hijacked a train carrying hundreds of passengers in Pakistan, authorities have said.
The Baloch Liberation Army (BLA) claimed responsibility for the attack and said they had killed 50 people on the train that was carrying more than 400.
Government officials have not confirmed how many hostages have been killed. Sarfraz Bugti, the chief minister in Balochistan province, said “we people have also been martyred, but we will share details later”.
More than 50 militants have been killed and the insurgent attack has now ended after a day-long stand-off, according to officials.
Image: A soldier stands guard next to a rescue train after the hijack by separatist militants. Pic: Reuters
Security officials told the Associated Press news agency that more than 300 hostages had been rescued.
Pakistan’s junior interior minister Talal Chaudhry said 70 to 80 attackers had hijacked the train.
A Pakistani government spokesman described the attack as “an act of terrorism”.
Passengers who have been freed described how gunfire was “coming from everywhere”.
Image: Passengers rescued by security forces from the hijacked train. Pic: AP
The train was hijacked on Tuesday as it entered a tunnel in Bolan, a district in the southwestern province of Balochistan.
The Jaffar Express was packed with 425 people, including women and children.
The train was on a 1,000-mile journey from Quetta to the city of Peshawar.
Militants blew up the railway tracks before firing at the train, killing the driver and trapping it inside a tunnel at Mashkaf.
Security forces exchanged gunfire with the militants who were wearing vests loaded with explosives.
Image: The train was hijacked as it entered a tunnel in Bolan, Pakistan
Image: Officials said a large number of the hostages had been rescued. Pic: AP
Noor Muhammad, who was travelling with his wife, said: “First, they hit the engine with an RPG (rocket-propelled grenade).
“After that, gunfire started and explosions were heard, RPGs were used. God saved us. They made us get off (the train) and told us to get down or they would shoot. We got down and then they said ‘leave’.”
Bashir Yousaf, who was with his family, said: “Everyone was crying and passengers were shouting, everyone was lying on the floor trying to save their lives.
“The sound of gunfire was coming from everywhere, then they (insurgents) told us to get down.
“After getting off we were told not to look back. I just kept walking without looking back to save my family’s lives.”
Image: A soldier keeps watch near to the scene of the hijacked train. Pic: AP
Image: Soldiers and police have been deployed at sites close to the hijacking. Pic AP
Pakistan’s Prime Minister Shehbaz Sharif condemned the attack and said security officials were “repelling” the militants, while interior minister Mohsin Naqvi called the attackers “enemies” of Pakistan.
The BLA had demanded the release of Baloch political prisoners, activists, and missing persons within 48 hours.
It had threatened to start executing the hostages if the government did not fulfil its demands.