New vaccines ‘ready in 100 days’ if Omicron variant is resistant to current jabs, Pfizer says

Published

4 years ago

November 27, 2021

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Vaccine manufacturers have expressed confidence that they will be able to rapidly adapt their jabs if the Omicron variant spreads.

The new strain – previously known as B.1.1.529 – features some “concerning” mutations, and early evidence suggests it brings an increased risk of reinfection.

There are also fears that the variant could be more resistant to the vaccines that have now been rolled out to billions of people around the world.

If this is the case, Pfizer and BioNTech expects “to be able to develop and produce a tailor-made vaccine against that variant in approximately 100 days, subject to regulatory approval”.

Moderna said it has advanced a “comprehensive strategy to anticipate new variants of concern” since early 2021 – including three levels of response if the immunity offered by its jabs wanes.

Novavax added it has already started creating a COVID-19 vaccine based on the known genetic sequence of B.1.1.529 “and will have it ready to begin testing and manufacturing within the next few weeks”.

Yesterday, the World Health Organisation designated B.1.1.529 as a “variant of concern”, meaning it has now officially been given the name Omicron, a letter from the Greek alphabet.

The strain was first detected in South Africa, and a number of countries – including the UK, Australia and the US – are now temporarily restricting travel to a number of European countries.

Follow live updates on the new COVID variant

Although no infections linked to the Omicron variant have been detected in the UK or the US so far, there has been a case in Belgium involving an unvaccinated person who had travelled abroad.

Salim Abdool Karim, one of South Africa’s top epidemiologists, told Sky News he “would expect it to be in the UK” by now.

Health Secretary Sajid Javid has warned that there is a “possibility it might have a different impact on individuals” who get coronavirus.

However, he stressed the UK remains in a “strong position” due to the high vaccination take-up – adding that Omicron’s presence means getting a booster jab is even more important now.

British scientists first became aware of the new strain on 23 November after samples were uploaded on to a COVID variant tracking website from South Africa, Hong Kong and then Botswana. A total of 59 samples have been uploaded so far.

Amid the concerns, flights to the UK from South Africa and five other southern African countries – Namibia, Lesotho, Botswana, Eswatini and Zimbabwe – have been suspended until 4am on Sunday.

These nations have now been added to the red list, and from Sunday, British nationals returning from these destinations will be required to quarantine in government-approved hotels for 10 days.

Mr Javid confirmed the government is still following Plan A for managing COVID-19 this autumn and winter but warned “if we need to go further, we will”.

England’s chief medical officer, Professor Chris Whitty, has said his “greatest worry” is whether the public would accept fresh restrictions if they were required.

World

It’s been a confusing week – and Trump’s been made to look weak

Published

3 hours ago

August 22, 2025

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It’s been a confusing week.

The Monday gathering of European leaders and Ukraine’s president with Donald Trump at the White House was highly significant.

Ukraine latest: Trump changes tack

The leaders went home buoyed by the knowledge that they’d finally convinced the American president not to abandon Europe. He had committed to provide American “security guarantees” to Ukraine.

The details were sketchy, and sketched out only a little more through the week (we got some noise about American air cover), but regardless, the presidential commitment represented a clear shift from months of isolationist rhetoric on Ukraine – “it’s Europe’s problem” and all the rest of it.

Yet it was always the case that, beyond that clear achievement for the Europeans, Russia would have a problem with it.

Trump’s envoy’s language last weekend – claiming that Putin had agreed to Europe providing “Article 5-like” guarantees for Ukraine, essentially providing it with a NATO-like collective security blanket – was baffling.

Russia gives two fingers to the president

And throughout this week, Russia’s foreign minister Sergei Lavrov has repeatedly and predictably undermined the whole thing, pointing out that Russia would never accept any peace plan that involved any European or NATO troops in Ukraine.

“The presence of foreign troops in Ukraine is completely unacceptable for Russia,” he said yesterday, echoing similar statements stretching back years.

Remember that NATO’s “eastern encroachment” was the justification for Russia’s “special military operation” – the invasion of Ukraine – in the first place. All this makes Trump look rather weak.

It’s two fingers to the president, though interestingly, the Russian language has been carefully calibrated not to poke Trump but to mock European leaders instead. That’s telling.

The bilateral meeting (between Putin and Zelenskyy) hailed by Trump on Monday as agreed and close – “within two weeks” – looks decidedly doubtful.

Maybe that’s why he went along with Putin’s suggestion that there be a bilateral, not including Trump, first.

It’s easier for the American president to blame someone else if it’s not his meeting, and it doesn’t happen.

NATO defence chiefs met on Wednesday to discuss the details of how the security guarantees – the ones Russia won’t accept – will work.

European sources at the meeting have told me it was all a great success. And to the comments by Lavrov, a source said: “It’s not up to Lavrov to decide on security guarantees. Not up to the one doing the threatening to decide how to deter that threat!”

The argument goes that it’s not realistic for Russia to say from which countries Ukraine can and cannot host troops.

Would Trump threaten force?

The problem is that if Europe and the White House want Russia to sign up to some sort of peace deal, then it would require agreement from all sides on the security arrangements.

The other way to get Russia to heel would be with an overwhelming threat of force. Something from Trump, like: “Vladimir – look what I did to Iran…”. But, of course, Iran isn’t a nuclear power.

Something else bothers me about all this. The core concept of a “security guarantee” is an ironclad obligation to defend Ukraine into the future.

Future guarantees would require treaties, not just a loose promise. I don’t see Trump’s America truly signing up to anything that obliges them to do anything.

A layered security guarantee which builds over time is an option, but from a Kremlin perspective, would probably only end up being a repeat of history and allow them another “justification” to push back.

Image and reality don’t seem to match

Among Trump’s stream of social media posts this week was an image of him waving his finger at Putin in Alaska. It was one of the few non-effusive images from the summit.

He posted it next to an image of former president Richard Nixon confronting Soviet leader Nikita Khrushchev – an image that came to reflect American dominance over the Soviet Union.

That may be the image Trump wants to portray. But the events of the past week suggest image and reality just don’t match.

The past 24 hours in Ukraine have been among the most violent to date.

World

What’s it like with the National Guard on the streets of DC?

Published

3 hours ago

August 22, 2025

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What's it like with the National Guard on the streets of DC?

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What’s it like on the streets of DC right now, as thousands of federal police patrol the streets?

Who is Steve Witkoff, the US envoy regularly meeting Vladimir Putin and Benjamin Netanyahu to broker peace in Ukraine and Gaza?

And why is Californian Governor Gavin Newsom now tweeting like Donald Trump?

Martha Kelner and Mark Stone answer your questions.

If you’ve also got a question you’d like the Trump100 team to answer, you can email it to trump100@sky.uk.

You can also watch all episodes on our YouTube channel.

World

At least 17 dead in Colombia after car bombing and helicopter attack

Published

3 hours ago

August 22, 2025

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At least 17 dead in Colombia after car bombing and helicopter attack

At least 17 people were killed after a car bombing and an attack on a police helicopter in Colombia, officials have said.

Authorities in the southwest city of Cali said a vehicle loaded with explosives detonated near a military aviation school, killing five people and injuring more than 30.

Authorities said at least 12 died in the attack on a helicopter transporting personnel to an area in Antioquia in northern Colombia, where they were to destroy coca leaf crops – the raw material used in the production of cocaine.

Antioquia governor Andres Julian said a drone attacked the helicopter as it flew over coca leaf crops.

Colombian President Gustavo Petro attributed both incidents to dissidents of the defunct Revolutionary Armed Forces of Colombia (FARC).

He said the aircraft was targeted in retaliation for a cocaine seizure that allegedly belonged to the Gulf Clan.

Who are FARC, and are they still active?

The Revolutionary Armed Forces of Colombia, a Marxist guerrilla organisation, was the largest of the country’s rebel groups, and grew out of peasant self-defence forces.

It was formed in 1964 as the military wing of the Colombian Communist Party, carrying out a series of attacks against political and economic targets.

In 2016, after more than 50 years of civil war, FARC rebels and the Colombian government signed a peace deal.

It officially ceased to be an armed group the following year – but some small dissident groups rejected the agreement and refused to disarm.

According to a report by Colombia’s Truth Commission in 2022, fighting between government forces, FARC, and the militant group National Liberation Army had killed around 450,000 people between 1985 and 2018.

Both FARC dissidents and members of the Gulf Clan operate in Antioquia.

It comes as a report from the United Nations Office on Drugs and Crime found that coca leaf cultivation is on the rise in Colombia.

The area under cultivation reached a record 253,000 hectares in 2023, according to the UN’s latest available report.