New vaccines ‘ready in 100 days’ if Omicron variant is resistant to current jabs, Pfizer says

Published

2 years ago

November 27, 2021

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Vaccine manufacturers have expressed confidence that they will be able to rapidly adapt their jabs if the Omicron variant spreads.

The new strain – previously known as B.1.1.529 – features some “concerning” mutations, and early evidence suggests it brings an increased risk of reinfection.

There are also fears that the variant could be more resistant to the vaccines that have now been rolled out to billions of people around the world.

If this is the case, Pfizer and BioNTech expects “to be able to develop and produce a tailor-made vaccine against that variant in approximately 100 days, subject to regulatory approval”.

Moderna said it has advanced a “comprehensive strategy to anticipate new variants of concern” since early 2021 – including three levels of response if the immunity offered by its jabs wanes.

Novavax added it has already started creating a COVID-19 vaccine based on the known genetic sequence of B.1.1.529 “and will have it ready to begin testing and manufacturing within the next few weeks”.

Yesterday, the World Health Organisation designated B.1.1.529 as a “variant of concern”, meaning it has now officially been given the name Omicron, a letter from the Greek alphabet.

The strain was first detected in South Africa, and a number of countries – including the UK, Australia and the US – are now temporarily restricting travel to a number of European countries.

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Although no infections linked to the Omicron variant have been detected in the UK or the US so far, there has been a case in Belgium involving an unvaccinated person who had travelled abroad.

Salim Abdool Karim, one of South Africa’s top epidemiologists, told Sky News he “would expect it to be in the UK” by now.

Health Secretary Sajid Javid has warned that there is a “possibility it might have a different impact on individuals” who get coronavirus.

However, he stressed the UK remains in a “strong position” due to the high vaccination take-up – adding that Omicron’s presence means getting a booster jab is even more important now.

British scientists first became aware of the new strain on 23 November after samples were uploaded on to a COVID variant tracking website from South Africa, Hong Kong and then Botswana. A total of 59 samples have been uploaded so far.

Amid the concerns, flights to the UK from South Africa and five other southern African countries – Namibia, Lesotho, Botswana, Eswatini and Zimbabwe – have been suspended until 4am on Sunday.

These nations have now been added to the red list, and from Sunday, British nationals returning from these destinations will be required to quarantine in government-approved hotels for 10 days.

Mr Javid confirmed the government is still following Plan A for managing COVID-19 this autumn and winter but warned “if we need to go further, we will”.

England’s chief medical officer, Professor Chris Whitty, has said his “greatest worry” is whether the public would accept fresh restrictions if they were required.

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Israel’s Benjamin Netanyahu rejects ceasefire deal that would ‘leave Hamas intact’

Published

3 hours ago

May 5, 2024

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Israel's Benjamin Netanyahu rejects ceasefire deal that would 'leave Hamas intact'

Israeli Prime Minister Benjamin Netanyahu has rejected ceasefire proposals because he says Hamas’s call for a withdrawal of all troops from Gaza and an end to the war is unacceptable.

Mr Netanyahu said agreeing to such proposals would “leave Hamas intact” and leave the possibility of another attack in future.

“Surrendering to the demands of Hamas would be a terrible defeat for the State of Israel,” he said in a video statement.

Mediated negotiations for a pause in the fighting in return for the release of hostages held by Hamas have been going on in Egypt, but a deal still appears some way off.

Hamas said in a statement on Sunday it’s “still keen to reach a comprehensive, interconnected agreement that ends the aggression, guarantees withdrawal, and achieves a serious prisoner exchange deal”.

The impasse comes after Egyptian media reported “noticeable progress” in ceasefire talks on Saturday.

The proposal mediators had put to Hamas set out a three-stage process for an immediate, six-week ceasefire and partial release of Israeli hostages, with some sort of Israeli pull-out in exchange.

More than 34,600 Palestinians have been killed and more than 77,000 have been wounded in Israel’s military operation, according to Gaza’s health ministry.

Israel has said it remains committed to a ground offensive in the southern city of Rafah, where more than a million have fled in search of safety, as it tries to wipe out Hamas.

The UN and others have warned of catastrophe if it goes ahead.

The war began in October after Hamas killed about 1,200 people, according to Israeli figures, when it launched a surprise attack.

More than 200 were abducted and many remain as hostages, while others are thought to have died.

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Health warning issued as heatwave grips South and Southeast Asia

Published

1 day ago

May 4, 2024

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Health warning issued as heatwave grips South and Southeast Asia

Countries in South and Southeast Asia have been coping with a weeks-long heatwave which has seen record temperatures sweep parts of the region.

Pupils in the Philippines, India and Bangladesh have been told to stay at home and learn remotely due to a severe health risk.

Schools in Cambodia have also cut back on their hours.

Cambodia faces its hottest temperature in 170 years, according to meteorologists – as high as 43C (109F).

Bangkok in Thailand has reached 40C (104 F), but the heat index is said to have topped 50 C (122 F) due to the heat being trapped among the mass of buildings.

The United Nations Children’s Fund warned in April that the heat could put the lives of millions of children at risk and asked people who care for them to take extra precautions.

A spokesperson for UNICEF said around 243 million children were exposed to hotter and longer heatwaves.

They said the increased heat was “putting them at risk of a multitude of heat-related illnesses, and even death”.

Thirty people in Thailand have died from heatstroke in the past month, according to data from the country’s health ministry.

People are being advised to avoid outdoor activities and to stay hydrated.

Several towns in Myanmar were included on lists of the hottest spots globally last month, with temperatures reaching 48.2C (118F) in at least one case.

Parts of eastern India also experienced their hottest April on record.

Kerala, on India’s west coast, this week instructed all schools and colleges to close until Monday, while influencers in Bangladesh have encouraging people to plant trees in response to the record heat.

Benjamin Horton, director of the Earth Observatory of Singapore, said there were three factors for heatwaves: a naturally-occurring climate phenomenon known as El Nino, an increase in global temperatures, and human-induced climate change.

Brazil is currently experiencing another climate phenomenon – La Nina – with 39 dead and 68 missing in floods across the country.

More than 24,000 people have been forced to leave their homes due to the flooding.

Scientists believe the naturally-occurring phenomenon has intensified due to the impact of climate change.

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Philippine coastguard hits out at China’s ‘brute force’ after water cannon attack

Published

1 day ago

May 4, 2024

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Philippine coastguard hits out at China's 'brute force' after water cannon attack

China has been branded “a bully” and an international lawbreaker after its ships blasted Philippine vessels with water cannon in the South China Sea.

Sky News was on board the BRP Bagacay when a Chinese vessel fired water at it, causing significant damage.

Philippine coastguard spokesman Jay Tarriela told Sky News that this week’s confrontation was the first time China had used “such aggression” against their ships.

“The metal parts and the railing were bent. The canopy was also destroyed. So this came as a surprise for us that China never hesitated to use brute force,” he said.

“It completely justifies us calling The People’s Republic of China a bully country.”

The Philippine coastguard was on a resupply mission to the Scarborough Shoal to deliver food and fuel to Philippine fishermen when they were struck.

The submerged reef lies in disputed waters. China claims sovereignty over the reef but it is much closer to the Philippines and lies within its legally recognised exclusive economic zone.

The vessel Sky News was on board was the closest the coastguard had ever been to the shoal – just 600 metres away from it.

Asked if the mission to the shoal was a provocative move by the Philippine coastguard, Commodore Tarriela denied they were “poking the bear” but rather “driving the bear out of our own territory”.

The Philippines has been stepping up its patrols in the area under the instruction of President Bongbong Marcos, and reasserting its claim to the shoal in recent months.

It has raised the spectre of open conflict. While neither side currently wants that, there is now a greater threat of open conflict.

Asked what the end game was for the Philippines, Commodore Tarriela said their priority was to “tell the world” about China’s aggression.

He said their secondary goal was to ensure “like-minded states” also made China “fall in line and respect international law”.

“Otherwise, it’s everybody’s loss,” he added.

Philippine government policy is not to resist using water cannon against Chinese vessels – and Commodore Tarriela insisted that policy remains in place after the confrontation.

The government also remains intensely determined to protect the waters it believes it has every right to operate in.

“We’re not going to yield and we’re not going to surrender a square inch of our territory,” Commodore Tarriela insisted.

Beijing has called the action its own coastguard took as “necessary”.

Speaking at the Chinese foreign ministry’s daily news conference, spokesperson Lin Jian described the coastguard’s conduct as “professional, proper, and lawful”.