Digital pharmacy startup Hims & Hers Health is introducing access to compounded GLP-1 weight loss injections, the company announced Monday.

Shares of the company jumped more than 30% Monday morning.

The company, which offers a range of direct-to-consumer treatments for conditions like erectile dysfunction and hair loss, launched a weight loss program in December. But GLP-1 medications — such as Ozempic and Wegovy, which have skyrocketed in popularity — were not previously offered as part of that program.

Customers can access the compounded GLP-1 medications via a prescription from a licensed health-care provider on the Hims & Hers platform. Hims & Hers said it plans to make branded GLP-1 medications available to its customers once supply is consistently available.

The company’s oral medication kits start at $79 a month, and its compounded GLP-1 injections will start at $199 a month.

Even before it added compounded GLP-1s to its portfolio, Hims & Hers said in its fourth-quarter earnings report that it expects its weight loss program to bring in more than $100 million in revenue by the end of 2025. The company plans to offer updated guidance in its next earnings report.

The GLP-1 market, dominated so far by pharmaceutical giant Novo Nordisk, has faced supply constraints in recent months as the drugs get expanded approval from health regulators and increased health coverage.

GLP-1s mimic a hormone produced in the gut to tamp down a person’s appetite and regulate their blood sugar. When those medications are in shortage, certain manufacturers can prepare a compounded version if they meet U.S. Food and Drug Administration requirements.

The FDA does not review the safety and efficacy of compounded products, which are custom-made alternatives to brand drugs designed to meet a specific patient’s needs.

In a January release, the FDA said patients should not use a compounded GLP-1 drug if an approved drug, such as Wegovy, is available.

Hims & Hers CEO Andrew Dudum told CNBC that the company is “confident” that customers will be able to access a consistent supply of the compounded medications.

Dudum said Hims & Hers has spent the last year learning about the GLP-1 supply chain and has partnered with one of the largest generic manufacturers in the country that has FDA oversight.

“We have a certain degree of exclusivity with that facility that will guarantee our consumers consistent volume and supply,” he said.

LONDON — The British government is expanding its facility for testing “frontier” artificial intelligence models to the United States, in a bid to further its image as a top global player tackling the risks of the tech and to increase cooperation with the U.S. as governments around the world jostle for AI leadership.

The government on Monday announced it would open a U.S. counterpart to its AI safety summit, a state-backed body focused on testing advanced AI systems to ensure they’re safe, in San Francisco this summer.

The U.S. iteration of the AI Safety Institute will aim to recruit a team of technical staff headed up by a research director. In London, the institute currently has a team of 30. It is chaired by Ian Hogarth, a prominent British tech entrepreneur who founded the music concert discovery site Songkick.

In a statement, U.K. Technology Minister Michelle Donelan said the AI Safety Summit’s U.S. rollout “represents British leadership in AI in action.”

“It is a pivotal moment in the U.K.’s ability to study both the risks and potential of AI from a global lens, strengthening our partnership with the U.S. and paving the way for other countries to tap into our expertise as we continue to lead the world on AI safety.”

The expansion “will allow the U.K. to tap into the wealth of tech talent available in the Bay Area, engage with the world’s largest AI labs headquartered in both London and San Francisco, and cement relationships with the United States to advance AI safety for the public interest,” the government said.

San Francisco is the home of OpenAI, the Microsoft-backed company behind viral AI chatbot ChatGPT.

The AI Safety Institute was established in November 2023 during the AI Safety Summit, a global event held in England’s Bletchley Park, the home of World War II code breakers, that sought to boost cross-border cooperation on AI safety.

The expansion of the AI Safety Institute to the U.S. comes on the eve of the AI Seoul Summit in South Korea, which was first proposed at the U.K. summit in Bletchley Park last year. The Seoul summit will take place across Tuesday and Wednesday.

The government said that, since the AI Safety Institute was established in November, it’s made progress in evaluating frontier AI models from some of the industry’s leading players.

It said Monday that several AI models completed cybersecurity challenges but struggle to complete more advanced challenges, while several models demonstrated PhD-level knowledge of chemistry and biology.

Meanwhile, all models tested by the institute remained highly vulnerable to “jailbreaks,” where users trick them into producing responses they’re not permitted to under their content guidelines, while some would produce harmful outputs even without attempts to circumvent safeguards.

Tested models were also unable to complete more complex, time-consuming tasks without humans there to oversee them, according to the government.

It didn’t name the AI models that were tested. The government previously got OpenAI, DeepMind, and Anthropic to agree to opening their coveted AI models up to the government to help inform research into the risks associated with their systems.

The development comes as Britain has faced criticism for not introducing formal regulations for AI, while other jurisdictions, like the European Union, race ahead with AI-tailored laws.

The EU’s landmark AI Act, which is the first major legislation for AI of its kind, is expected to become a blueprint for global AI regulations once it is approved by all EU member states and enters into force.

The boss of travel and expense management platform Navan told CNBC he’s preparing the company to get its business into shape for an eventual initial public offering this year, in another sign leaders of privately-held startups are getting more optimistic about their prospects in the public markets.

Asked about when Navan would choose to go public, the firm’s CEO and co-founder Ariel Cohen said the company is close to reaching that milestone. “We can see the signals,” he said, adding that Navan has been adjusting its leadership structure and making changes to its board in a signal of maturity.

Last month saw Navan announce the return of Rich Liu, formerly Navan’s chief revenue officer and “an expert on scaling companies from seed to IPO and beyond,” to the business as CEO of Navan Travel, the company’s travel division.

Amy Butte, the former chief financial officer of the New York Stock Exchange who oversaw the U.S. exchange operator’s transition to a public company in 2006, was also appointed to Navan’s board of directors as audit committee chair.

“I don’t want to give a date,” Cohen told CNBC, adding that he’s not even told his own family a date for when he expects Navan to go public — let alone his board and Navan employees. “At the end of the day, there are things that are out of my control.”

“The market can collapse. There are elections in the U.S. There are wars. So I never actually promise things to people if I don’t know that the delivery is in my control,” he added.

While Cohen wouldn’t commit to a date for Navan’s eventual IPO, he said the business was “not far” from being ready for a stock market listing. The company is on track to become cash-flow positive and achieve profitability for the first time this year, he said.

“The timing will need to include several things,” he said. “Today, in this market, to be public, you need to be profitable. We are not far from that, but we are not there. We’re going to be there this year. And it’s not easy to do it while you’re growing fast.”

Cohen said he’s also keeping a wary eye on the market — but added that although, previously, investors would have seen a company like his as dependent on buoyant market sentiment surrounding technology, today he sees the firm as “mature enough” to go public independent of the market backdrop.

Navan is now growing revenues by around 40% on average, according to Cohen, with the company’s fintech business seeing faster growth (100%) than its travel business (30%).

Founded in 2015 as TripActions, Navan began life as a travel management platform for businesses, seeking to provide a smoother experience to travel agents and incumbent players like American Express, BCD Travel, and SAP Concur. The company counts the likes of Unilever and Christie’s as clients.

The firm subsequently expanded into expensing and payments with solutions for automating linking credit cards to a single platform and automating expenses.

Navan is backed by major investors including Andreessen Horowitz, Coatue, Goldman Sachs, and Lightspeed. Navan has raised more than $1.5 billion in venture funding to date and was last valued at $9.2 billion. It competes with Spanish startup TravelPerk, which was most recently valued at $1.4 billion.

Navan introduced a big evolution of that product last year with the arrival of Navan Connect, a new expensing product.

Most corporate card startups, like Brex and Ramp, offer users their own branded corporate smart cards. But Navan’s Connect feature, which it’s rolled out in partnership with Citi, lets businesses offer automated expense management and reconciliation without having to change corporate card provider.

Like other tech firms, Navan has been making a big investment into artificial intelligence. The company rolled out its own AI personal assistant, called Ava, last year. The tool uses generative AI to help travelers, travel admins, and finance managers make travel plans and budget effectively.

Ava — which stands for automated virtual assistant — now processes around 150,000 monthly chats, more than 35% of which are managed to completion as of April 2024, according to Navan.

Cohen said Navan is planning to roll out an even more personalized version of Ava’s AI assistant, which can generate travel plans for someone based on their past behavior, to even greater accuracy in six months’ time.

Navan was named on the 2024 edition of CNBC’s Disruptor 50 list.