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Nearly 100,000 cancer patients have now had fast-track access to newly approved NHS drugs – with one teen saying his treatment felt like being on a “slope going up”.

Yuvan Thakkar, 16, was the first NHS patient to receive a therapy that uses the body’s own cells to fight cancer.

He was diagnosed with a form of leukaemia aged six and received the pioneering treatment at Great Ormand Street Hospital.

The CAR-T therapy, called tisagenlecleucel (Kymriah), involved removing his immune cells and modifying them to recognise and destroy cancer cells, before reintroducing them to the body.

In April, the NHS will have helped 100,000 patients access new and innovative treatments over eight years.

It’s been made possible by the NHS Cancer Drugs Fund – set up in 2016 to give patients faster access to new treatments.

The fund benefits people with common cancers, such as breast, lung, colorectal and prostate; as well as those with less common ones such as ovarian, cervical, kidney, and leukaemia – and also rare cancers including thyroid and biliary tract.

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NHS England said patients get access to National Institute for Health and Care Excellence (NICE) approved treatments six months faster, and all cancer treatments are funded as soon as they are approved.

For Yuvan, who spent his childhood in hospital fighting leukaemia, faster access to the CAR-T therapy means he is now able to sit his GCSEs.

Recounting his treatment, he said: “I remember receiving the cells for a bit. I was feeling quite down” – before being sent to intensive care “where I couldn’t do basic counting and things like that”.

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The 16-year-old pictured with his family and (below) painting for his art GCSE

Painting for his art GCSE

The teenager said he doesn’t remember any of his treatment until it was finished.

“I thought I could start to get better, then I remembered, ‘oh, I can do this, I can do that’. And from now on, it’s just been like a slope going up,” said Yuvan.

Concern as cancer targets cut

Professor Sir Stephen Powis, the NHS England medical director, said treating 100,000 people was “a fantastic milestone”.

He said: “This vital fund is helping ensure patients get access to the most promising drugs far quicker than would otherwise be the case, helping people with cancer like Yuvan receive a life-changing intervention that sets a path for a longer, healthier life spent with family and friends”.

However, Professor Pat Price, a leading oncologist and co-founder of the Catch Up With Cancer campaign, is concerned about those still struggling to get treatment due to the backlog of cancer cases.

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Since the pandemic, she said 250,000 patients have not had their treatment on time.

National guidance states 85% of people should begin treatment within two months, or 62 days, of an urgent referral, but Professor Price said there has been a downgrade in ambition.

She told Sky News: “We are in the biggest cancer crisis we’ve ever had. This week the NHS have reset their targets for 2025 and sadly, they’ve pushed their recovery target for cancer.”

She said the target for next year had been cut from 85% to 70%.

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Rishi Sunak to argue UK is safer under Conservatives amid worsening global outlook

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Rishi Sunak to argue UK is safer under Conservatives amid worsening global outlook

Rishi Sunak will argue that Britain is safer under the Conservatives against the backdrop of two escalating conflicts likely to dominate the week.

In the last few days, the prime minister has broken with US President Joe Biden by insisting the UK should continue to supply arms to Israel.

It comes as Israeli PM Benjamin Netanyahu appears poised to mount another massive military operation in the southern Gaza town of Rafah against warnings from the US and UK.

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Meanwhile, there are fears in Whitehall that Russia could mount an operation on Kharkiv by the end of the week to retake Ukraine‘s second-largest city.

Both operations could trigger wider repercussions.

Amid this worsening global outlook, the Conservatives want to highlight what they say is the gap between Tory and Labour pledges on military spending.

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Rishi Sunak at the Catterick Garrison in North Yorkshire on 3 May. Pic: AP
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Rishi Sunak at the Catterick Garrison in North Yorkshire on 3 May. Pic: AP

Sunak announced last month that a future Tory government would ensure 2.5% of GDP will be spent on the military by 2030, while Labour says it will do it when the economic conditions allow.

After the initial announcement, Sunak wants to ensure he gets full public credit for the big spending commitment while pushing Labour on its failure to match the promise.

Labour says that the Tory spending plan does not add up.

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Israel arms embargo ‘not a wise path’

On Monday, Sunak will use a set-piece speech to mount the argument that there is a need for security at home and abroad in an ever-increasingly dangerous world and describe the country as being at a crossroads at the next general election.

In a further major political dividing line, Labour has broken with the government and called this weekend for a suspension of arms to Israel, placing it alongside the United States.

However the Tory government is holding firm, arguing that now is not the time and that Britain only supplies a small amount of the munitions used by Israel.

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Some people inside government suggest that the US government position is driven by President Biden’s need to take a tougher position to shore up votes in the upcoming election race.

Sunak’s Monday speech is one part of a set of security-themed announcements by the government, following Lord Cameron’s media blitz at the weekend.

On Monday, deputy foreign secretary Andrew Mitchell will address a Tory-leaning think tank, while on Tuesday Defence Secretary Grant Shapps will make a speech, with Chancellor Jeremy Hunt speaking on Friday.

Also, Deputy Prime Minister Oliver Dowden will lead a trade delegation this week to Saudi Arabia.

Although boosting trade will be the focus, Saudi Arabia, like Qatar, is one of the backchannels used by the UK to deliver messages to Hamas.

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Three men charged with assisting Hong Kong’s intelligence service and foreign interference

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Three men charged with assisting Hong Kong's intelligence service and foreign interference

Three men have been charged with offences under the National Security Act including assisting Hong Kong’s intelligence service and foreign interference.

Chi Leung (Peter) Wai, 38, Matthew Trickett, 37, and Chung Biu Yuen, 63, will appear at Westminster Magistrates’ Court today, the Metropolitan Police said.

It follows an investigation led by officers from the Met’s counter terrorism command in which 11 people in total were detained.

Eight men and a woman were arrested by officers on 1 May in the Yorkshire area, before a man was arrested in London and another man was arrested in the Yorkshire area the following day, the force said.

The seven men and one woman who were not charged were released from custody on or before 10 May.

Commander Dominic Murphy, head of the Met’s counter terrorism command, said: “A number of arrests were made and searches carried out across England as part of this investigation.

“While these offences are concerning, I want to reassure the public that we do not believe there to be any wider threat to them.

“This investigation remains ongoing, but now that charges have been brought, I urge people not to speculate or comment further in relation to this case.”

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Wai, of Staines-upon-Thames, Trickett, of Maidenhead, and Yuen, of Hackney, are each charged with assisting a foreign intelligence service and with foreign interference, contrary to the National Security Act.

“The foreign intelligence service to which the above charges relate is that of Hong Kong,” the Met Police said.

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‘Serious questions’ for lenders over surge in ultra-long mortgages

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'Serious questions' for lenders over surge in ultra-long mortgages

Young homebuyers are being forced to gamble with their retirement prospects by taking on ultra-long mortgages, according to a former pensions minister.

Sir Steve Webb described data – supplied by the Financial Conduct Authority to the Bank of England – as “shocking”.

It suggests that more than one million new mortgages have been issued over the past three years with end dates beyond the state pension age.

The ex-Liberal Democrat MP, who is now a partner at the consultancy firm LCP, voiced fears that borrowers could be forced to raid their pension savings to clear their mortgage in a worst-case scenario.

Sir Steve saw the potential for harm in any case, as longer-term mortgages deprive people of a period running up to retirement when they could be mortgage-free and boosting their pension.

According to the Freedom of Information data requested, 42% of new mortgages in the fourth quarter of 2023 – or 91,394 – had terms going beyond the state pension age.

The figure stood at 38% in the same period a year earlier.

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In the final quarter of last year, people aged 30 to 39 accounted for 30,943 new mortgages lasting beyond state pension age, while people aged 40 to 49 accounted for 32,305.

Under-30s made up 3,676 of these mortgages.

People aged 50 to 59 accounted for 18,854, and there were 661 who were over 70.

Mortgage rates have been rising since the end of 2021 when the Bank of England began action to tackle rising inflation.

Taking home loans with longer maturity dates tends to be more attractive when interest rates are high, as monthly repayments are lower.

Steve Webb was pensions minister in the coalition Government
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Sir Steve Webb was pensions minister in the coalition government

Sir Steve said: “The huge number of mortgages which run past state pension age is shocking.

“The challenge of getting on the housing ladder is forcing large numbers of young homebuyers to gamble with their retirement prospects by taking on ultra-long mortgages.

“We already know that millions of people are not saving enough for their retirement and if some of that limited retirement saving has to be used to clear a mortgage balance at retirement they will be at even greater risk of poverty in old age.

“Serious questions need to be asked of mortgage lenders as to whether this lending is really in the borrower’s best interests.”

The FCA’s responsible lending rules require lenders to take account of future changes to income and expenditure, such as the borrower retiring, where this was expected to happen during the mortgage term.

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‘Path is downwards’ on interest rates

Emily Shepperd, the FCA’s chief operating officer, admitted in a speech to the Building Societies Association last week that lending into retirement was moving “from a niche to a norm”.

“Alongside longer terms we also see a greater proportion of mortgages projected to mature around state retirement age,” she said.

“The projected median age of a first-time buyer at maturity is now 65 years old, up from 56 in 2005.

“The proportion of mortgage customers over 67 is currently less than 2% of all loans. By 2040 this rises to 5%, and by 2050 it is almost 10%.”

She said that building societies recognise the need to consider different income and expenditure sources and needs, different lifestyle risks and different capacity to weather financial shocks, adding: “With borrowers projected to hold debt for longer, now is the time to ask yourself about the products and services you will provide to those borrowers to meet their needs responsibly and help them meet their financial goals – what will you need to do to support this growing population of customers and deliver good outcomes?

“Getting this right will of course benefit those individual customers, enabling them to meet their housing needs in later life, and move if that is their aim.

“It may also support first-time buyers with an increase in the supply of homes.”

Karina Hutchins, principal for mortgage policy at lenders’ body UK Finance, said: “The proportion of longer-term mortgages has been increasing in recent years as buyers to look for ways to stretch their affordability.

“When reviewing new mortgage applications, lenders will act within the responsible lending rules set by the Financial Conduct Authority and carefully consider whether the borrower will be able to afford their mortgage in the future.

“This will include whether the requested term would take the borrower beyond their anticipated retirement age.

“Where this is the case, it is common practice for lenders to request proof of pension. Those closer to retirement, usually within 10 years, may need to satisfy their lender that they can afford the mortgage based on their retirement income.

“Whilst longer mortgage terms can offer lower initial monthly repayments, the borrower will pay more in interest and have less disposable income to put into their pension if the mortgage runs for its full term.

“We would encourage customers to speak to an independent mortgage adviser to discuss the best options available for their specific circumstances,” she concluded.

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