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A powerful animal tranquilliser plaguing cities in the US has now “penetrated” the illegal drugs market in the UK, a report has warned.

Xylazine – often referred to as “Tranq” or “the zombie drug” because of its effect on users – has already been labelled an “emerging threat to the nation” by the White House.

The drug was linked to a UK death for the first time during a post-mortem of Karl Warburton, found dead at his home in Solihull in May 2022.

In most cases, the tranquilliser is mixed or “cut” with strong opioids such as heroin or fentanyl by dealers aiming to lower their costs and increase demand.

Users often develop skin sores and infections where they inject and have previously told Sky News that the mix increases their addiction.

Last year, amid rising deaths attributed to xylazine, the White House announced a six-point plan to tackle the problem.

Researchers, led by academics from King’s College London, say the health threat has “now expanded to the United Kingdom”.

Their study, published in the journal Addiction, examined various toxicology, drug testing and drug seizure sources.

While usually mixed with illegal drugs, it found xylazine had been discovered in counterfeit prescription medication tablets, THC (tetrahydrocannabinol) vapes, and cocaine.

Danielle, a mother of three. Until a couple of years ago, Danielle worked as a certified recovery specialist to support people in rehab. She shows the wounds on her arms.
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Tranq users can develop sores or infections

What is xylazine?

In the hands of vets, xylazine is a commonly used tranquilliser, often mixed with ketamine to sedate animals, including horses, cattle, and cats.

As a non-opioid sedative, it is able to inhibit the transmission of brain impulses to the central nervous system. But in recent years, it has become synonymous with a darker usage, as a cutting agent for illegal drugs such as heroin.

In the US, its mixture with fentanyl has had a widespread impact among drug users in American cities. Such is the concern in Washington about its spread, that Joe Biden’s administration has labelled it an emerging threat to the nation and outlined a six-point plan to tackle it.

There it has gained the nicknamed “tranq” or “the zombie drug” – because of its characteristic effect of putting users into a zombie-like state. But it has, perhaps, an even more grim side effect on users, who often develop skin sores and infections where the drug is injected.

Xylazine’s usage appears to be increasing at an alarming rate. From November 2021 until August 2022, 80% of drug paraphernalia which tested positive for fentanyl at needle exchange programmes in Maryland also contained xylazine.

And in May last year, the first death following its usage was recorded outside the US – Karl Warburton who died at his home in Solihull in May 2022.

Researchers found 35 cases of xylazine in England, Scotland and Wales by the end of August last year. No cases were found in Northern Ireland.

They published data on samples from toxicology labs, where the drug was found in 16 people – including 11 who had died.

Eleven of the samples were from summer last year.

They also referenced the death of Mr Warburton, who the coroner said had a history of using illegal drugs.

Karl Warburton, 43, died of an overdose last May Pic: Facebook
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Karl Warburton had xylazine in his system when he died. Pic: Facebook

Read more:
How alarming rise in deaths linked to Tranq made White House act

A post-mortem on the 43-year-old found he had heroin, fentanyl and cocaine in his system, as well as xylazine.

A report in the Journal of Forensic and Legal Medicine said he was “likely to have bought heroin and not known it was laced with xylazine and fentanyl”.

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Senior author Dr Caroline Copeland, from King’s College London, said: “We now know that xylazine has penetrated the UK’s illicit drug market.

“This is cause for alarm as a much wider population of people who use drugs beyond heroin users will be exposed to its harms.

“We also know that most people who buy heroin will not intend to buy xylazine and this combination increases the risk of overdose.

“Xylazine was designated an ’emerging threat’ to the United States and this public health threat is a growing concern for the UK.”

Read more from Sky News:
Drug dealer disguised cannabis as Wonka chocolate bars
Dealer caught trying to smuggle cocaine by hiding it inside table

Dr Copeland urged the government to introduce “simple” measures to prevent an epidemic of xylazine, including testing strips and making healthcare providers aware of the signs of xylazine use.

She also said pathologists and coroners should request toxicology testing for xylazine in relevant cases to understand its true prevalence.

Despite the results of the study, Manchester-based MANDRAKE, England’s first publicly-funded city centre testing and harm reduction facility, said it hadn’t yet detected the substance in samples from 2022 to the start of 2024.

A government spokesperson said: “We are aware of the threat from xylazine and are determined to protect people from the threat posed by this drug and other illicit synthetic drugs.

“We will not hesitate to act to keep the public safe.

“Following advice from the Advisory Council on the Misuse of Drugs (ACMD), we intend to make xylazine a Class C drug, meaning anyone supplying this substance will face up to 14 years in prison, a fine or both.”

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Rishi Sunak apologises to infected blood scandal victims and says it is ‘day of shame for British state’

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Rishi Sunak apologises to infected blood scandal victims and says it is 'day of shame for British state'

Prime Minister Rishi Sunak has offered a “wholehearted and unequivocal” apology to the victims of the infected blood scandal, saying it was a “day of shame for the British state”.

Mr Sunak said the findings of the Infected Blood Inquiry’s final report should “shake our nation to its core”, as he promised to pay “comprehensive compensation to those infected and those affected”, adding: “Whatever it costs to deliver this scheme, we will pay it.”

The report from the inquiry’s chair Sir Brian Langstaff blamed “successive governments, the NHS, and blood services” for failures that led to 30,000 people being “knowingly” infected with either HIV or Hepatitis C through blood products. Around 3,000 people have now died.

The prime minister said for any government apology to be “meaningful”, it had to be “accompanied by action”.

Politics live: Thatcher’s health secretary ‘disparaging’ to infected blood victims

Speaking in the Commons, Mr Sunak called it a “calamity”, saying the report showed a “decades-long moral failure at the heart of our national life”, as he condemned the actions of the NHS, civil service and ministers – “institutions in which we place our trust failed in the most harrowing and devastating way”.

The prime minister said they “failed this country”, adding: “Time and again, people in positions of power and trust had the chance to stop the transmission of those infections. Time and again, they failed to do so.

“I want to make a whole-hearted and unequivocal apology for this terrible injustice.”

Victims and campaigners outside Central Hall in Westminster.
Pic; PA
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Victims and campaigners outside Central Hall in Westminster.
Pic: PA

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Pointing to key findings in the report – from the destruction of documents through to failures over screening – Mr Sunak said there had been “layer upon layer of hurt endured across decades”.

He also apologised for the “institutional refusal to face up to these failings and worse, to deny and even attempt to cover them up”, adding: “This is an apology from the state to every single person impacted by this scandal.

“It did not have to be this way. It should never have been this way. And on behalf of this and every government stretching back to the 1970s, I am truly sorry.”

Labour leader Sir Keir Starmer also apologised for his party’s part in the scandal, telling the Commons: “I want to acknowledge to every single person who has suffered that in addition to all of the other failings, politics itself failed you.

“That failure applies to all parties, including my own. There is only one word, sorry.”

Read more:
100 faces of the infected blood scandal
Analysis: Report makes for difficult reading – but vindicates victims
The day as it happens as ‘chilling’ cover-up laid bare

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Infected blood victims ‘betrayed’ by NHS

In his report, released earlier on Monday, Sir Brian issued 12 recommendations – including an immediate compensation scheme and ensuring anyone who received a blood transfusion before 1996 was urgently tested for Hepatitis C.

He also called for compensation – something Mr Sunak said would come and would be outlined in the Commons on Tuesday.

But speaking to Sky News’ Sarah-Jane Mee, he warned the “disaster” of the scandal still wasn’t over, saying: “More than 3,000 have died, and deaths keep on happening week after week.

“I’d like people to take away the fact that this is not just something which happened. It is happening.”

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Inquiry chair Sir Brian Langstaff spoke to Sky’s Sarah-Jane Mee.

Sir Brian said what had happened to the victims was “no accident”, adding: People put their trust in the doctors and the government to keep them safe. That trust was betrayed.

“And then the government compounded the agony by repeatedly saying that no wrong had been done.”

But he hoped the report would ensure “these mistakes are not repeated”.

He told Sky News: “We don’t want another 30,000 people to go into hospital and come out with infections which were avoidable, which are life-shattering, which were no accident.

“And we don’t want the government to end up being defensive about them – but instead to be candid [and] forthcoming in the ways which I’ve just suggested.”

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Infected Blood Inquiry: Who is criticised in new report?

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Infected Blood Inquiry: Who is criticised in new report?

An inquiry into the infected blood scandal has pointed the finger at several people and organisations after more than 30,000 patients were “knowingly” infected with HIV or Hepatitis C.

Inquiry chair Sir Brian Langstaff said the “disaster was not an accident” and there was a “catalogue of failures” and a “pervasive” cover-up by the NHS and successive governments.

More than 30,000 Britons were infected with HIV and Hepatitis C after being given contaminated blood products in the 1970s and 1980s.

About 3,000 people died as a result, while many more still live under the shadow of health problems, debilitating treatments and stigma.

Follow live: Updates on infected blood report

Speaking after the report was published on Monday following the seven-year inquiry, Sir Brian said: “The damage caused was compounded by the reaction of successive governments, the NHS and the medical profession.

“Successive governments refused to admit responsibility to save face and expense.

More on Health

“Today’s report also found that the response to the infections made things worse, including repeated failures by governments and the NHS to acknowledge the victims should not have been infected in the first place.”

In the report, he named specific people and institutions in his criticism.

They included:

Lord Clarke

Kenneth Clarke, now a lord, was heavily criticised by Sir Brian.

He was a health minister in Margaret Thatcher’s government from 1982 to 1985, then health secretary from 1988 to 1990.

Ken Clarke
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Ken Clarke was later John Major’s chancellor. Pic: PA

Lord Clarke was accused of being “somewhat blasé” when he gave evidence to the inquiry about the collection of blood from prisoners as late as 1983.

His manner was described as “argumentative”, “unfairly dismissive” and “disparaging” towards those who have suffered, with Sir Brian saying he played “some part” in that suffering.

The report said it was “regrettable that he could not moderate his natural combative style in expressing views”.

Sky News has approached Lord Clarke for comment.

Read more: 100 faces of infected blood scandal

Chairman of the infected blood inquiry Sir Brian Langstaff with victims and campaigners outside Central Hall in Westminster.
Pic:PA
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Inquiry chairman Sir Brian Langstaff with victims and campaigners. Pic: PA

The Thatcher government

Margaret Thatcher, as well as subsequent governments and health secretaries, continually said infections were “inadvertent” and patients were given “the best treatment available on the then current medical advice”.

The inquiry report concluded that was not true and said the factual basis for the claim was unclear.

“In short, adopting the line amounted to blindness,” the report said.

“Adopting it without realising it needed to have a proper evidential base, and they did not know what it was, was unacceptable.

“The line, which was wrong from the very outset, then became entrenched for around 20 years: a dogma became a mantra.

“It was enshrined. It was never questioned.”

The Prime Minister Margaret Thatcher speaking at the 1980 Conservative Party Conference in Brighton.
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Margaret Thatcher. Pic: PA

Sir Brian added that the Thatcher government “did not respond appropriately, urgently and proactively” to the risks of Hepatitis C and HIV transmissions through blood.

He said the government knew there was a much higher incidence of Hepatitis in prisoners, yet “no action” was taken to stop blood donations from them, which “increased the risk of transmission”.

The failure lied “principally at the door” of the health departments in Westminster and Scotland, he said.

He said the Thatcher government signed up to recommendations in 1983 from the Council of Europe to inform clinicians and patients about the risks of treatment – yet failed to follow those recommendations.

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Infected blood scandal ‘no accident’

Sir Brian described the failure to provide any guidance to doctors about the risk of transmission of AIDS as “inexcusable”.

On compensation, he also said the Thatcher government “plainly formed the view, at an early stage, that nothing had been done wrong, and that no financial assistance would be provided to people with bleeding disorders who had been infected with HIV”.

He added: “It did so without any proper investigation either into what had caused the infections or into the appalling plight of those infected.”

Treloar School

Haemophiliac children were sent to the Hampshire school with an on-site NHS clinic so they could live as near a normal childhood as possible.

Instead, 75 boys died of AIDs and Hepatitis – and 58 were infected but survived – as they were included in secret trials to test a blood product called Factor 8, which was made with blood farmed from prisoners, sex workers and drug addicts in America.

The report said there “is no doubt” the risks of virus transmission were well known to doctors at Treloar School, yet doctors “played down the risks”.

Stephen Nicholls, (3L), with other Treloar students from the 1970s and 1980s at the inquiry
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Treloar students from the 1970s and 1980s at the inquiry. Pic: PA

Some pupils and parents were “never informed” by the school the boys had tested positive for HIV, which Sir Brian said “was unconscionable”.

Treloar School was a “microcosm” of much of “what went wrong in the way haemophilia clinicians treated their patients across the UK,” he added.

The school said in a statement: “We are devastated that some of our former pupils were so tragically affected and hope that the findings provide some solace for them and their families.”

It added that its management was “absolutely committed to exploring” calls for a public memorial to those affected, and added: “We’ll now be taking the time to reflect on the report’s wider recommendations.”

Alder Hey Children’s Hospital

The hospital was the main site in Liverpool for children with bleeding disorders from the late 1970s onwards.

Doctors used Factor 8 concentrate containing contaminated blood to treat them, even after other haemophilia centres stopped using them on children, Sir Brian found.

Alder Hey’s director from the mid-1970s, Dr John Martin, “did not regard the risk of Hepatitis as a reason to alter any treatment regime”, the report added.

“He exposed them to wholly unnecessary risks,” it said.

Sky News has approached Alder Hey for comment.

Alder Hey Children's Hospital in Liverpool admitted a 'breach of duty'
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Alder Hey Children’s Hospital in Liverpool. Pic: PA

Professor Arthur Bloom

Professor Bloom, who died in 1992, was one of the country’s leading haemophiliac specialists during the period and treated some of those who were affected.

Sir Brian Langstaff said he “must bear some of the responsibility for the UK’s slowness in responding to the risks of AIDs to people with haemophilia”.

Prof Bloom said at the time he was unaware of any proof linking infections to the blood products and said there was no need to change patients’ treatment, Sir Brian said.

He added: “Disastrously the Department of Health and Social Security was over-influenced by his advice, in particular his advice to continue importing commercial factor concentrates.”

Professor Arthur Bloom, who died in 1992, was one of the country's leading haemophiliac specialists. From Ashish Joshi report on infected blood inquiry and interview with Colin and Jan Smith
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Professor Arthur Bloom

The NHS

Sir Brian said the response of the NHS and the government showed there was not a major plot to cover up failures “in an orchestrated conspiracy to mislead”.

“But in a way that was more subtle, more pervasive and more chilling in its implications,” he said.

“To save face and to save expense, there has been a hiding of much of the truth.”

He also found patients were knowingly exposed to unacceptable risks of infection, with transfusions frequently given when not clinically needed.

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‘Day of shame for the British state’

The report also said there was no contact tracing exercise carried out when Hepatitis C screenings were introduced.

Sir Brian also said the NHS and governments repeatedly failed to acknowledge people should not have been infected, despite the scandal being known about.

Prime Minister Rishi Sunak on Monday offered a “wholehearted and unequivocal” apology to victims and said it was a “day of shame for the British state”.

He said the findings of the inquiry should “shake our nation to its core” and promised to pay “comprehensive compensation to those infected and those affected.”

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Labour: ‘There was systemic failure’

The NHS said in a statement on its website: “Since September 1991, all blood donated in the UK is screened using very rigorous safety standards and testing to protect both donors and patients.

“Since screening was introduced, the risk of getting an infection from a blood transfusion or blood products is very low.”

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Infected blood report will give survivors some satisfaction – but prosecutions must wait for another day

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Infected blood report will give survivors some satisfaction - but prosecutions must wait for another day

Of all the survivors of this scandal I have spoken to, the key demand they have from this inquiry is accountability.

They want the organisations and individuals who contributed to this scandal to be clearly identified, held to account and – where evidence is sufficient – prosecuted.

The inquiry report clearly identifies where the fault lies.

Live updates:
Infected blood scandal report latest

Organisations like the Department of Health and the NHS are singled out for their failure to prevent the infection of tens of thousands of individuals in the first place.

It goes on to implicate them in the denial, delay and a clear attempt at “hiding the truth”.

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Infected blood victims ‘betrayed’ by NHS, says inquiry chair

Then there are the committees, such as the Committee on Safety of Medicines.

More on Health

The inquiry finds it should never have approved potentially infected blood products for use in the NHS given what was known at the time, let alone what came to light as people began to die as a result of receiving them.

Individuals are clearly identified too, many of them now deceased; the directors of the UK’s blood transfusion centres who failed to act on warnings about the safety of our domestic blood supply.

Hundreds of individual doctors also failed to recognise the risk to their patients, were slow to test them for illnesses then inform them of the results, and in some cases used them in clinical trials for medicines known to be risky that led to some dying unnecessarily.

Read more:
The stories behind 100 victims
‘I gave my young son to his killers’
Infections are ‘worst thing you can imagine’

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Clarke singled out

Senior civil servants and ministers are singled out also.

Kenneth, now Baron, Clarke – who was health minister between 1982 and 1985 – comes in for specific criticism.

Inquiry chair Sir Brian Langstaff said it was “indefensible” that the government’s position in 1983 was that there was “no conclusive proof” of the risk of HIV to the UK blood supply and blood products.

There will be some satisfaction for survivors that so many organisations and individuals are criticised. But when it comes to legal culpability, and the prospect of prosecutions, they must wait for another day.

Read more on Sky News:
Nursery worker guilty of manslaughter over death of baby
Investigation after man in his 30s dies in police custody
Some of £5bn spend on post-Brexit border checks ‘unnecessary’

Inquiries can’t find criminal responsibility

Under the Inquiries Act, public inquiries are prohibited from finding criminal or civil liability.

If any prosecutions are to come from this report, it will be through the courts.

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