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From Revvity Apr 26 2024 Reviewed by Laura Thomson

Revvity, Inc. (NYSE: RVTY) has announced the launch of the Auto-Pure 2400 liquid handler from Allsheng for use with the T-SPOT.TB test. The Auto-Pure 2400 platform is easy to use and designed to provide efficient workflows in the lab. When the accuracy of the T-SPOT.TB test is combined with the efficiency of the Auto-Pure 2400 system, labs, clinicians and ultimately patients, benefit from the resultant powerful solution.

“The ability to use the Auto-Pure 2400 platform with our T-SPOT.TB test provides labs an efficient workflow allowing latent TB testing to be run in a mid-high-volume setting, without having to compromise on the clinical performance of the test,” said Darren Sher, general manager, infectious diseases for Revvity. “With this solution, more labs can offer clinicians access to the most accurate TB diagnostic on the market.” Related StoriesLaunching Revvity: A Scientific Solutions Company Powering Innovation from Discovery to CureRentschler Biopharma licenses Horizon Discoverys CHOSOURCE platform to complement cell line development offering for difficult-to-express proteinsRevvity Signals Software unveils Signals Clinical solution to accelerate critical clinical trial insights and data-driven decisions

Auto-Pure 2400 liquid handler for use with the T-SPOT.TB test The Auto-Pure 2400 automated liquid handling platform is equipped with integrated magnetic cell isolation technology. Designed for testing up to 24 samples per run, it completes day-1 T-SPOT.TB workflows in under 3.5 hours, requiring only a single mid-run user interaction. The solution simplifies lab workflows and boasts an intuitive software user interface.

About the T-SPOT.TB test The T-SPOT.TB test detects latent tuberculosis infection (LTBI) and is an interferon-gamma release assay (IGRA) based on the enzyme-linked immunospot (ELISPOT) technology. This technology has crucial steps that the World Health Organization has recently recognized as critical in ensuring reliable and accurate TB test results. These steps include washing, isolating, and counting peripheral blood mononuclear cells (PBMCs) before conducting the test.

Products may not be licensed in accordance with the laws in all countries. Please check with your local representative for availability.Source:

https://www.revvity.com/gb-en

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Cubs’ Bellinger back from IL, not ‘fully pain-free’

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Cubs' Bellinger back from IL, not 'fully pain-free'

CHICAGO — The Chicago Cubs activated center fielder Cody Bellinger from the injured list while placing pitcher Daniel Palencia on it, the team announced Tuesday afternoon.

Bellinger, 28, has been out with a rib injury since running into the wall at Wrigley Field on April 23. He’ll be the designated hitter Tuesday and Wednesday against the San Diego Padres before the team decides if he is ready to play the outfield again.

Bellinger said he is not 100% healed yet.

“It takes a bit of time to be fully pain-free,” he said Tuesday before the game. “It’s a matter of pain tolerance. I feel like I’m in a good spot with it.”

Bellinger took batting practice Monday, ran the bases and performed drills in the outfield before being cleared.

“Ribs feel good,” Bellinger said. “Had a good test, facing some live pitching. Felt like it was a good time to come back.”

Bellinger was hitting .226 with five home runs and an OPS of .760 before his injury. The Cubs could also play him at first base moving forward as rookie Pete Crow-Armstrong has played well in center field since being called up from Triple-A Iowa. The plan, though, is eventually to get Bellinger back in center field.

“You want to have your best players in the lineup,” manager Craig Counsell said. “You want to put your best team out there as much as you can. Getting Cody back puts us in a step in the right direction.”

Outfielder Alexander Canario was optioned to Triple-A Iowa to make room for Bellinger on the roster.

Palencia was placed on the injured list after feeling pain in his right shoulder on the final pitch he threw in Monday’s win over San Diego. The team is awaiting MRI results to determine his next course of action. Right-hander Keegan Thompson was recalled from Triple-A to take his place.

Joining Canario in Iowa will be right fielder Seiya Suzuki, who will begin a two-day rehab assignment before joining the big league team in Pittsburgh on Friday. He has been out since mid-April after injuring his right oblique while running to first base.

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MLB: Don’t push kids to drop out to evade draft

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MLB: Don't push kids to drop out to evade draft

Major League Baseball has sent a warning to clubs about encouraging players subject to the MLB draft to withdraw from high school baseball to become eligible to sign as international players. An MLB spokesman declined comment.

The key section of the memo sent to teams Monday and obtained by ESPN reads: “It has come to our attention that Clubs have been encouraging amateur players in the United States to withdraw from, or otherwise refrain from playing, high school baseball in the United States and/or Canada, in order to try to establish residency in a foreign country, in an effort to make themselves eligible to sign under the International Amateur Talent System instead of the Rule 4 Draft.”

In the MLB draft, picks largely cannot be traded, so teams’ access to elite players is largely determined by their draft order. In the international system, teams have similar-sized bonus pools, and any player is able to be negotiated with. All but the best handful of players are acquirable by every team in the international market.

In the memo, the league clarified the rules around eligibility and what rules teams were breaking by encouraging players to change their eligibility. The memo says that encouraging players to make this change “shall be subject to significant penalties, including, but not limited to, the denial of player selection rights under the [MLB draft] or loss of benefits under the International Amateur Talent System.”

A recent example of a legal version of this maneuver was made by shortstop Lucius Fox in 2015. He was a native of the Bahamas who had moved to Florida to play high school baseball and was regarded as a fringe first-round prospect after his junior year of high school. Fox moved back to the Bahamas and was declared a free agent by the league in April 2015, eventually signing for $6 million with the San Francisco Giants in July 2015.

The international bonus pools weren’t hard-capped then like they are now, so that sort of bonus is unlikely, but this illustrates the potential benefit of this kind of move. Fox would’ve received roughly half that bonus if he had stayed in the draft process, but he was evaluated differently as an 18-year-old in the international market, where the biggest bonuses are largely given to 16-year-old prospects. Fox, now 26 years old, is a free agent. He has played in 10 big league games, all in 2022 for the Washington Nationals.

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Braves reliever Matzek to IL with elbow injury

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Braves reliever Matzek to IL with elbow injury

ATLANTA — The Braves lost another reliever to an injury on Tuesday when they placed left-hander Tyler Matzek on the 15-day injured list with left elbow inflammation.

The Braves place right-hander Pierce Johnson on the 15-day IL on Sunday with right elbow inflammation.

The move with Matzek came after he allowed three runs while recording only two outs in Saturday night’s 11-2 loss to the Los Angeles Dodgers. The 33-year-old has a 9.90 ERA in 11 games this season, allowing 11 runs in 10 innings.

Matzek was a key reliever for Atlanta’s 2021 World Series championship team. He had a 2.57 ERA in 69 games but had Tommy John surgery on his left elbow in 2022 and missed the 2023 season.

Braves manager Brian Snitker said Matzek reported soreness in his elbow on Monday, when the team was off. Snitker said the inflammation following Tommy John surgery is not unusual.

“I think that’s the biggest thing, just get him calmed down and get him back right,” Snitker said.

The Braves recalled left-hander Ray Kerr from Triple-A Gwinnett before Tuesday night’s game against the Boston Red Sox.

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